Gene Information

Name : hemC (lpa_03992)
Accession : YP_003620088.1
Strain : Legionella pneumophila 2300/99 Alcoy
Genome accession: NC_014125
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3199216 - 3200070 bp
Length : 855 bp
Strand : +
Note : COG0181, HemC, Porphobilinogen deaminase [Coenzyme metabolism]

DNA sequence :
ATGCTTGTAAAGCAATGGCCAAATCTAAGCATTGAATTATTACCCATGATAACCTCTGGCGATCGGTTTCTTAAAGATAA
ATTATTATCCGCAGGAGGAAAAGGGTTATTTGTTAAAGAGTTAGAAGAAGCATTATTGGATAAAAGAGCGGACTTGGCTG
TTCATTCGACCAAAGACATGCCAGCACAACTTCCGGATGGCCTCTTGTTGGCCGCCATTTGCAAAAGAGATAACCCTTTT
GACGCTTTAATAAGTCCCCAATTTAAGAGTCTGGATGCTCTCCCCAAAAACGCAATTATCGGTACATCAAGCCTTAGACG
TCAATCTCAGCTATTGGCTTACAATCCCAATTTGCAAATCAAAACATTAAGAGGAAACATCCATACAAGACTCAGCAAAC
TGGAGTCTGGAGAGTATCAAGCCATTATTCTTGCTGCCGCAGGCTTGGAAAGAATGGGCTTAGCACATCACATCACCCAA
CTCATACCCGATGACATTATGCTGCCTACTTGTGCTCAGGGCGCTTTATGTATTGAGTGCCGAACGGATGATTTGGAAAT
CCAAGAGCTGATTCATGGCTTAAATGATCCAATTTCTGCCCTTTGTGTCCATACCGAGCGACGCGTCAACGCAAAATTAG
GAGGCAATTGCCATATACCCTTTGCTGTTTATTGTACCATTACTGAGGAGAAACGCCTCCTTTTGAGAGCAAAAGTACTT
AATATGGATGGTTCTCAAATGATTGATGATGAGCAACAAGGGAAAATTGCAGAAGCTGAAGTCATTGCAGACAGGTGTAC
CGAGTCATTAATGACTAAAGGTGCAATGTCCTTATTGAGTACGATACCATCATGA

Protein sequence :
MLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVHSTKDMPAQLPDGLLLAAICKRDNPF
DALISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLESGEYQAIILAAAGLERMGLAHHITQ
LIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCVHTERRVNAKLGGNCHIPFAVYCTITEEKRLLLRAKVL
NMDGSQMIDDEQQGKIAEAEVIADRCTESLMTKGAMSLLSTIPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-59 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-59 48