Gene Information

Name : lpa_02776 (lpa_02776)
Accession : YP_003619212.1
Strain : Legionella pneumophila 2300/99 Alcoy
Genome accession: NC_014125
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2228171 - 2228923 bp
Length : 753 bp
Strand : -
Note : COG1212, KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase [Cell envelope biogenesis, outer membrane]

DNA sequence :
ATGAGCCATAATTTTCATGTGATTATACCAGCCAGATATCACTCCAGTCGTTTTCCAGGTAAATTACTTCAAGAAATTAA
CGGCATTACTGTGATTGAACGAGTTTACAGGCAAGCACTTCTGGCAGAACCAAAGTCGGTGATTATTGCCACTGATCATG
ATGAGATAGCTGACCGTGCAATCCAATTTGGAGCGGAGGTTGTAATCACTTCACATACGCACCAAACTGGAACTGATCGA
ATTGCAGAGGTTGTCGCCAAGGGTAGCTTTGCTCCTGATGACGTCATTGTCAATGTGCAAGGTGATGAGCCATTTATCCG
ACCCAAATTAATTCAACAAGTTGCTTGCTCTTTAACGAAGACAAAGGCGCCTGTGTCTACTTTATGCTGGCCTATTAGTA
GCCTTGAAATATTAAATAACCCTAATGTGGTTAAAGTGGTGTGCACTCGAGATAATCACGCTCTTTATTTTTCAAGAAGC
GCAATTCCTTATCACAGAGATAATAAAAGCGCTTATTCCAATACCTTCAGGCATATCGGTTTATATGCTTATCGTGCTGC
CTTTTTACTGGAATTCGTTAGCTGGCCACCCTGTACCTTGGAACAAATAGAGTGTTTGGAGCAATTGCGCATCCTATGGT
CAGGTTTCTCAATCCGGGTTGATGAGGCCTGTGAAGAACCTTTACAGGATATTAATACAAAAGAAGATTTGATTTTGGCT
CAGCAATATTTTCTTGATACTTCCAATATATAA

Protein sequence :
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPYHRDNKSAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDTSNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-36 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-36 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-36 42