Gene Information

Name : clpA (lpa_02537)
Accession : YP_003619041.1
Strain : Legionella pneumophila 2300/99 Alcoy
Genome accession: NC_014125
Putative virulence/resistance : Unknown
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2025183 - 2027759 bp
Length : 2577 bp
Strand : +
Note : -

DNA sequence :
ATGCGAATGGACAAACTAACATCAAAGTTTCAAATGGCTCTTGCAGATGCCCAATCCCTGGCTTTAGGTAGAGACAATGG
ATTTATAGAACCAGAACATTTAATGAAAGCCTTGCTTGATCAGCAAGGCGGAAGTTGCAGACCTCTTCTCAGTAAAGCGG
GTGTTAATATACCACTATTAAGAACTTTAATTGACCAAGCTCTGGATAAACTCCCTAAAGTATCAGGCACCGGAGGAGAT
ATTCATATATCTAATGCATTGAATAGACTACTTAACCTGACTGACAAATTATCGCAACAAAGAAAAGATAACTTTATTTC
AAGCGAGCTTTTTGTATTAGCAGCGATAAATGAGGATAGTAACCTTGCAAAAATACTCAAACAAGCCGGGGGTGACAACA
AAGCAATTGAAAAAGCGATTGATGAGTTAAGAGGTGGAGAAACGGTTAATGATCCAAATGCAGAGGAACAGCGACAAGCC
CTTGAAAAATATACACTGGATCTGACTGAACGTGCCGAGCAAGGAAAATTGGACCCAGTGATTGGGCGAGATGATGAAAT
CAGACGCACCATCCAGGTATTGCAAAGAAGAACCAAAAATAACCCTGTATTAATAGGTGAACCTGGTGTTGGTAAAACAG
CCATAGTAGAAGGTTTGGCACAACGAATTATTAATGGTGAAGTACCTGAAGGATTAAAGAATAAACGCTTACTGGCACTG
GACATGGGTGCCTTGATCGCGGGTGCAAAATATCGTGGAGAGTTTGAAGAACGTTTAAAAGGTGTGCTTAATGATTTGGC
AAAACAAGAGGGTCAAATCATATTATTTATTGATGAATTACACACTATGGTTGGCGCTGGCAAGGCTGAAGGAGCTATGG
ATGCCGGGAATATGCTCAAGCCAGCATTGGCTAGAGGTGAATTGCATTGCATTGGGGCTACGACATTAGACGAATACCGA
CAATACATTGAAAAGGATGCTGCCCTTGAACGACGCTTTCAAAAAGTACTGGTCGATGAACCCAGTGTGGAAGACACTAT
CGCTATATTAAGGGGACTTAAAGAACGTTATGAAGTTCACCATGGAGTTGAAATTACAGATCCCGCTTTGGTTGCTGCAG
CAATGCTATCCCATCGTTACATCAGCGACCGTCAGCTACCTGATAAAGCCATTGATTTAATTGATGAAGCCGCCAGCTTA
ATCCGGATGGAAATTGATTCAAAACCAGAAAGTATGGATAAACTGGAACGACGTTTGATTCAGCTAAAAATCGAGCGTGA
AGCATTGAAAAAGGAAAATGATGAAGCGTCTAAAAAAAGACTTGTTGATTTACAAAAAAGTATCGATGAATTAGAGCAAA
ATTATTCAGACTTAGAAGAAATTTGGAAAGCTGAAAAAGCGACCATGCAAGGTTCCACTCAAATCAAAGAAGCACTTGAG
CAAGCCAAACTGGAAATGGAAACTGCAAGGAGAGCAGGAGATTTAAGTCGCATGTCCGAATTACAATATGGGCGTATACC
CGAGTTGGAAAAAAGATTAAGCCAGGTCTCTTCCGTCGATGCTATGGAAACAAAGTTGGTACGCAATAAAGTCACCGAAG
ATGAGATAGCAGAAGTTGTTTCAAAATGGACAGGGATCCCCGTATCTAAAATGATGGAAGGAGAAAAGGAAAAACTGCTG
AAAATGGAAGAAGCTTTGCACAGCAGACTCATTGGCCAGAATGAAGCGGTGGATGCTGTTTCTAATGCCATAAGACGGTC
ACGCGCAGGCCTGTCTGATCCTAACCGTCCAATTGGTTCATTTCTTTTTCTGGGGCCAACTGGTGTGGGAAAAACTGAAC
TATGTAAAGCACTTGCTTCTTTTCTTTTTGATACGGAAGAGGCGATGGTGCGTATTGATATGTCTGAATTTATGGAAAAA
CACTCTGTTGCGCGCTTAATCGGAGCGCCTCCTGGCTATGTAGGATATGAGGAGGGTGGTTATTTAACTGAAGCAGTCAG
ACGCAGGCCCTATTCTGTTATCTTACTTGATGAAGTAGAAAAAGCTCATACAGATGTATTTAATATTCTGCTTCAAGTGA
TGGATGATGGCCGTCTAACAGATGGTCAGGGACGTACTGTTGACTTTAGGAATACCGTTATTGTTATGACCTCTAATCTG
GGATCTCAACTCATTCAGGAAATGAGCAGCAAATTTAATTACGATGAGATTAAGGCTGCGGTAATGGATTTAGTCAGCCA
ACATTTCAGACCTGAATTTATCAACAGAATTGATGAATCGGTGGTATTCCATTCCCTGACAAAAGAACAAATTGCAAAAA
TTGCAGCAATCCAGATTAACTATTTACATCATCGGCTGAAACAACAAAACATCACTCTTGAAGTCACAAGTGAGGCTTTA
TCTCATTTGGCTGAAGCAGGATTTGATCCGGTCTATGGTGCCCGCCCTCTAAAACGTACTATTCAGCAAAAATTAGAGAA
TCCCCTAGCTCAATCATTATTGACTGGAAAATTTAAATCAGGGGATACCATTATTGTATCTTATAAAGACGGAGTAATGG
AATTTTCCAAGCAATGA

Protein sequence :
MRMDKLTSKFQMALADAQSLALGRDNGFIEPEHLMKALLDQQGGSCRPLLSKAGVNIPLLRTLIDQALDKLPKVSGTGGD
IHISNALNRLLNLTDKLSQQRKDNFISSELFVLAAINEDSNLAKILKQAGGDNKAIEKAIDELRGGETVNDPNAEEQRQA
LEKYTLDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKNKRLLAL
DMGALIAGAKYRGEFEERLKGVLNDLAKQEGQIILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYEVHHGVEITDPALVAAAMLSHRYISDRQLPDKAIDLIDEAASL
IRMEIDSKPESMDKLERRLIQLKIEREALKKENDEASKKRLVDLQKSIDELEQNYSDLEEIWKAEKATMQGSTQIKEALE
QAKLEMETARRAGDLSRMSELQYGRIPELEKRLSQVSSVDAMETKLVRNKVTEDEIAEVVSKWTGIPVSKMMEGEKEKLL
KMEEALHSRLIGQNEAVDAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALASFLFDTEEAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHTDVFNILLQVMDDGRLTDGQGRTVDFRNTVIVMTSNL
GSQLIQEMSSKFNYDEIKAAVMDLVSQHFRPEFINRIDESVVFHSLTKEQIAKIAAIQINYLHHRLKQQNITLEVTSEAL
SHLAEAGFDPVYGARPLKRTIQQKLENPLAQSLLTGKFKSGDTIIVSYKDGVMEFSKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-154 45
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-98 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-100 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 7e-100 41