Gene Information

Name : lpa_01829 (lpa_01829)
Accession : YP_003618506.1
Strain : Legionella pneumophila 2300/99 Alcoy
Genome accession: NC_014125
Putative virulence/resistance : Virulence
Product : two-component system response regulator PilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 1422469 - 1423797 bp
Length : 1329 bp
Strand : +
Note : COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]

DNA sequence :
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCGCGTATGGG
TTTAGCTTGCGATGCAGCGTCTGACTTTAAGCAAGGTGTAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTGCCTGATGGAGATGGTATAGAAATTGTTAAATTTATTCAGAAATACAAACCACAGGTGCCAGTTGCTGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCAGTCAATACTTTAAAGGCGGGTGCATTTGATTATGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTGGTTAAGACGGCATTATCCATGCAAAACCCGTCTACCGAGAGGCCTGATGAGAGTCTAT
TGGTTGGTGAAAGTTTGGTCATGCAACAACTTCGTGAAAGCATTCATAAATTAGCTCGCAGTCAGGCACCGGTTTTTATT
CAAGGGGATTCAGGTGTTGGAAAAGAACTGGTCGCTCAGTTGATCCATGCTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCTATACCTGGTGAGTTGATGGAGTCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGCTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTGTTACGTGCTATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAAGAAGTTAATGCCGGGATGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTTCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAATTATCTAAAAATCAAAATAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGCCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATTCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCCAGAACAACAATAACCCCAGTTGTTGCCGTATCCCCCGCGTCGACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCTCAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGTCTTGATTAG

Protein sequence :
MTKSKVLVIDDEPDIRELLTLTLSRMGLACDAASDFKQGVEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQVPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPSTERPDESLLVGESLVMQQLRESIHKLARSQAPVFI
QGDSGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGMFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPVVAVSPASTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 4e-98 49
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 4e-98 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpa_01829 YP_003618506.1 two-component system response regulator PilR BAC0467 Protein 2e-78 42
lpa_01829 YP_003618506.1 two-component system response regulator PilR BAC0089 Protein 8e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpa_01829 YP_003618506.1 two-component system response regulator PilR VFG1214 Protein 9e-132 60