Gene Information

Name : lpa_01458 (lpa_01458)
Accession : YP_003618251.1
Strain : Legionella pneumophila 2300/99 Alcoy
Genome accession: NC_014125
Putative virulence/resistance : Virulence
Product : nucleoside-diphosphate sugar epimerase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 1153691 - 1155568 bp
Length : 1878 bp
Strand : +
Note : COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]

DNA sequence :
GTGGTTTTTATAATGCAAAAAATAATCATATTGACAAAAAAAATCATTGCAAAACTCCCAGTAATTTTGTTTGATGTGGC
CGCAATACCAGTTGCCTGGTATGCCGCTTACTGGTTGCGCTATAACATGCAGCCATATCCCAGCAGCCTGACATCCACCC
ATTCTTTTATTGCTTTAGCTTTATTATCAATTGTTCAGATTAGTTGTTACTATTATTTTAAAATTTACAGAGGATTATGG
CGTTTCTCTTCTCTGAATGATGTCATCAGGATACTGAAGGCTACTATCACAGCAATGGTTTTAGTAATCCCTGTTTTTTA
CTTGACTTCAATTCTTCAGCACCTGCCCAGATCAGTTTTTCCTTTGTATTGCATTATCCTGGCTACCATCCTTTGCGGGG
GAAGGTTGGTGATCCGTCTGCATTGGGATAAGCCTGGCAGAGGAAACAGGGAATTGGAAACGAAAAGAGTTTTGGTGGTT
GGTGCCGGGCAGGCTGGTGAAGGCTTGGTGCGTGATTTGAAAAGAAGCAGTTATTATCGGCCAATAGGCTTTGTAGATGA
CAATAAAAGCAAGAGAGGATTAGAAGTTCATGGAGTGCGGGTTCTGGGAACGACTAACCAAATTACCGAATTAGTCAATC
AGTACGACGTGGATTTGATTTTCATTGCCATACCTTCTGCCAAATCGGCAACCATGCGAAGAATTGTAACGCTTTGTGAA
CAAAGCCATGTGCCTTTTAGTACTTTACCCAGTATTTCAGCCCTGGCTGCGGGCCGGGTTGAAGTGAATGCGCTGAGGCC
TGTGAATATTGAGGATTTATTGGGTCGGGATCAAGTGACGCTCGAATGGGAAAAAATTGCTCGTTCAATAGCAGGAAGAC
GCATATTGATTACAGGCGGTGGTGGCTCAATCGGTTCGGAATTGTGCCGTCAGGTTATGGCTTTAGAGCCTGCGAGCATA
GCCATTGTTGAGAATAGTGAGTTTAACCTGTATCGCATTGAACAGGAGTTGTTAAAGAGTTTTCCAGGTATCCCCGTTGA
ATTGAGTTTAATCAGTGTGACAGACGAAATTGCGATTAATCACTTATTTCGTCGGTTTCAACCTGAAATTGTATTTCATG
CGGCTGCTTACAAACATGTTCCCATGCTTCAGCATCAAGTACGGGTTGCTGTGTTTAATAATGTCATAGGTACTCAGGTT
GTTGCCAAAGCCAGTGTGACATTCGGAGCTGAGAAATTCATTTTAATTTCCACTGATAAAGCAGTGAATCCAACGAATAT
AATGGGAACTACCAAGAGAGTCGCTGAAATTTATTGTCAGAATTTAAATACACGAGTTAAAACCCAGTTTATTACGGTTC
GTTTTGGAAATGTTCTGGGTTCAGCTGGAAGTGTGGTGCCTTTGTTCCAAAAGCAGTTGCAGGAAGGTGGTCCACTGACT
GTGACCCATCCCGATATGCAAAGATATTTTATGACTATACCGGAAGCATGCCAGTTGATTTTGCAAGCGATGGTGAATGG
GGAGGGTGGTGAAATTTTTGTCCTGGATATGGGAGAGCCGGTTAAAATCAGCTATCTTGCAGAGCAAATGATTCGCTTGG
CAGGCAAAGAACCAGGAAGAGACATCATGATTGAATATACAGGTTTGCGTCCTGGCGAAAAAATGTATGAAGAGTTGTTT
CATGAGACTGAACAGTTAACTTCAACAAAACATGAAAAATTATTCAAAGCAAGGTTTCGTGAACTGGATTGGAATGATTT
GACACAAACCATGCGAATGTTACAGGCAGCTTGTATTGAGCATCAGGATGAGGAGTTGCTTGTTCTGTTAAAAAGTCTGG
TGCCGGAGTTTCAATTGGAACCTATGGTTGAAGCTTAA

Protein sequence :
MVFIMQKIIILTKKIIAKLPVILFDVAAIPVAWYAAYWLRYNMQPYPSSLTSTHSFIALALLSIVQISCYYYFKIYRGLW
RFSSLNDVIRILKATITAMVLVIPVFYLTSILQHLPRSVFPLYCIILATILCGGRLVIRLHWDKPGRGNRELETKRVLVV
GAGQAGEGLVRDLKRSSYYRPIGFVDDNKSKRGLEVHGVRVLGTTNQITELVNQYDVDLIFIAIPSAKSATMRRIVTLCE
QSHVPFSTLPSISALAAGRVEVNALRPVNIEDLLGRDQVTLEWEKIARSIAGRRILITGGGGSIGSELCRQVMALEPASI
AIVENSEFNLYRIEQELLKSFPGIPVELSLISVTDEIAINHLFRRFQPEIVFHAAAYKHVPMLQHQVRVAVFNNVIGTQV
VAKASVTFGAEKFILISTDKAVNPTNIMGTTKRVAEIYCQNLNTRVKTQFITVRFGNVLGSAGSVVPLFQKQLQEGGPLT
VTHPDMQRYFMTIPEACQLILQAMVNGEGGEIFVLDMGEPVKISYLAEQMIRLAGKEPGRDIMIEYTGLRPGEKMYEELF
HETEQLTSTKHEKLFKARFRELDWNDLTQTMRMLQAACIEHQDEELLVLLKSLVPEFQLEPMVEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-81 43
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 4e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpa_01458 YP_003618251.1 nucleoside-diphosphate sugar epimerase VFG1300 Protein 3e-81 41