Gene Information

Name : ECL_00407 (ECL_00407)
Accession : YP_003610922.1
Strain : Enterobacter cloacae ATCC 13047
Genome accession: NC_014121
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 424571 - 426724 bp
Length : 2154 bp
Strand : +
Note : -

DNA sequence :
ATGCGGCTATTTATCTGTGAAAAACCCTCGCAGGGGCGCGATCTGGCCGGGGTTCTCGGTGCCACCCGGCGCGGTGACGG
CTTTCTGACCGGCAGCGGAGTCACCGTCACCTGGGCAGTGGGGCACCTGCTGGAAACCGCACCGCCCGAGGCGTACGGTC
AGCAATACGGTAAACCGTGGTCACTTTCGGCACTGCCGATCCTGCCTGCCCCCTGGCGGGTTGTGGTCAAAAAAGAGACG
CAGGATCAGTTCAAAGTCATCGAGCGGCTGCTGCGACAGGTTGACGATGTGGTTATTGCCACTGATGCAGATCGGGAGGG
GGAGGTCATTGCGCGTGAGCTGCTGGAATACTGCCGCTGGGAAGGTCCGGTGCAGCGGCTCTGGCTGTCTGCGCTGGATG
AACTCAGTATCCGCGCGGCGCTTCAGGACCTGCGTCCCGGTCAGGCCACGCTCGGGATGTATCACGCCGGACTGGGGCGT
GCCCGGGCCGACTGGCTGATAGGTATGAACCTCTCCCGTCTTTATACCCTGCGCGCAGCGGAGTCCGGTTTTGATGGCGT
GGTCTCCGTGGGGCGTGTTCAGACGCCAACGCTGGCGCTGGTTGTCCGACGGGACCGGGAAATCGCAGCATTTGTGCCGA
AACCGTTCTGGCAGGTTAAAGCGCTTATTTCCGCCGGTGACCTCACCTTTCCGGCGCAGTGGGTGCCGGCGAAGGTGTAT
ACCGACGAGGAAAAGCGCTGTGTTCACCAGAACATCGCGCAGCAGGTGGCACAGCTCTGCCGGCAGACAGGTCACGCCGT
GGTGACCGAATGTGACACTAAGCGTGAAAAAGCCGCCGCGCCACTGGCGTTTTCCCTCGGGTCCCTGCAGCAGGCCTGTG
GCAGGCTGTGGGATATGTCCCCGCAGCAGGTGCTTGATACTGCCCAGAGCCTGTATGAAAAGCACAAGGCCACGACCTAC
CCCCGTACCGACTGCGGTTACCTGCCGGAATCGATGCGGGAGGAGATTTCCGGTGTGCTTGATGCCATCGGCCGTACCGA
CCCGGAATGTGCGCCGGTGCTGGCTCGCCTCGACAGAACATTTGTCTCGCGCATCTGGAACGACAAAAAAATTACGGCAC
ACCACGGCATTATCCCCACCCGCAATGCGTTTCAGCTGTCCGCGCTGACGGAGACCGAGCGTAACGTCTATATGCTCATC
CGCCGTAACTATCTGGCCCAGTTCCTCCCCCTGCATGAGTCCGATTTCACACGGCTGCAGTTCGACACTGGCGGGCAGCT
GTTCCGTGCCACCGGGCGAACGGAGGTGATAAAGGGCTGGAAGGTTCTGTTTGAGAACGCTGGTGATAATGAAGTTGATG
ACGGCGATGAAGCAGACATTGCCCTGCCGCCGCTGGCGCAGAATGACCGCTGCGCGGTGACGGGGGCTGAGGTGGTGCAA
CTGATGACCCGTCCGCCGGCGCACTATACCTTTGCCACGCTGATTGGCGCCATGATGAACGCGGCAGCATTTGTCACCGA
CGTCGCGCTGCGCAAGGTGCTGAAAGACAACGCGGGACTGGGCACCGAAGCCACCCGCGCCGGTATTGTTGAGCAACTGC
TGAACCGTCACTTTATCGTGCGTAAAGGCAGTAAAATCATGGCGACCGAACTGGGTGCCGATGTGATTGATGCCCTGCCG
CCGCAACTGACCGAACCGGGCATGACGGCGCTGTGGGAACAGGCGCTGGATGAGGTCGCCGCCGGGCGTATGTCACTCGA
CGACTTCCTGCAGCGGCAGACTGGCTGGACGCGTAACCTGGTCAGTCAGGGCACACAGCAGCAGGTGCGTATCCGGGTTC
CGCCCACGCCCGCCTGCCCGCTCTGCGGGGGAAAACCCGTCTGCGCAGGGGAGAGAAAGGGGAATTCTGGAGCTGCCAGC
GCTGGCCGGAATGCAAAGGTGTCATCAACATCGGGGGCACCAGAAAGAAACGACCGCGCAGGGCTAAGTCTCCTGAATCA
AAGAAGAATTAATCCTCTGTATCCGATTGCGGGGCGTTGTGGGCTCTGCTATTGTGACCCCGGCTCTGAAGCCGCACCCC
GTGACTGCGGGTTTCGTCAGCATCTAATGCATGTGCTGCCGGAATACAGTCTGGCCGGCCCCGTCCACACCTGA

Protein sequence :
MRLFICEKPSQGRDLAGVLGATRRGDGFLTGSGVTVTWAVGHLLETAPPEAYGQQYGKPWSLSALPILPAPWRVVVKKET
QDQFKVIERLLRQVDDVVIATDADREGEVIARELLEYCRWEGPVQRLWLSALDELSIRAALQDLRPGQATLGMYHAGLGR
ARADWLIGMNLSRLYTLRAAESGFDGVVSVGRVQTPTLALVVRRDREIAAFVPKPFWQVKALISAGDLTFPAQWVPAKVY
TDEEKRCVHQNIAQQVAQLCRQTGHAVVTECDTKREKAAAPLAFSLGSLQQACGRLWDMSPQQVLDTAQSLYEKHKATTY
PRTDCGYLPESMREEISGVLDAIGRTDPECAPVLARLDRTFVSRIWNDKKITAHHGIIPTRNAFQLSALTETERNVYMLI
RRNYLAQFLPLHESDFTRLQFDTGGQLFRATGRTEVIKGWKVLFENAGDNEVDDGDEADIALPPLAQNDRCAVTGAEVVQ
LMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRHFIVRKGSKIMATELGADVIDALP
PQLTEPGMTALWEQALDEVAAGRMSLDDFLQRQTGWTRNLVSQGTQQQVRIRVPPTPACPLCGGKPVCAGERKGNSGAAS
AGRNAKVSSTSGAPERNDRAGLSLLNQRRINPLYPIAGRCGLCYCDPGSEAAPRDCGFRQHLMHVLPEYSLAGPVHT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 61
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 61
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 1e-177 57
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-163 53
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 8e-161 52
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 4e-149 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-147 49
topB AAW83109.1 TopB Not tested GGI Protein 3e-115 41