Gene Information

Name : mrfC (ECL_01106)
Accession : YP_003611616.1
Strain : Enterobacter cloacae ATCC 13047
Genome accession: NC_014121
Putative virulence/resistance : Virulence
Product : fimbrial biogenesis outer membrane usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 1139703 - 1142186 bp
Length : 2484 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAAACGATACGGACATTCCGACGCTCAACGCTCAGCGTGCTGATTTTGGCTTTAATCGTGCCGGTGGCGAAAAG
CTGGGCCGACGATGATATTCAGTTCAATACCGACGTGCTGGACACGCAGGACAAGAGCAATATCGATCTTAGCCACTTTT
CGCGTCGAGGCTACGTCATGCCCGGCGACTACACCTTCAGCATCATGGTGAACAAAGACATCCTGCGCGAAGAGCGAATT
GTGGTCTATCCCGAGGGTGAAAACGGCCGGGACAGCCTGATTTGCCTTACGCCAGAGCAGCTCTCTCGCTTCAACCTGAA
GGCCAGCGTCATGGACGATCTTCGCTGGCTGCGCGACGGTGAGTGTCTGGACAAAGCCAGTCTCGAAGGGCTGGATATGC
GCGTCGACCTTGCAAAGGACACGCTTTATCTGGCGATCCCACAGGCGTGGCTGGAGTACACTGCGCCAAACTGGGATCCG
CCTTCGCGCTGGGATGAGGGTATCCCTGGTGTGATTGCCGACTACAACCTCAATGTTCAGGCGCAGCAGAATAAAACCGG
TTCAGACAGCCAAAATATCAGCGGGAATGGGGTCCTGGGGGCCAACCTGGGACCATGGCGTGCCCGCGCCGACTGGCAGA
CCAGCTGGTACAAGCGTGACGGGAAAACGGACAAGGATTTCGCCTTTAGCCGTTACTACCTCTACCGCGCCATTCCTTCA
CTGAAAGCGAAGCTGACGGTGGGGGAAGATTACCTCAGCTCCGATATCTTCGATACCTTCCGCTTTAGCGGCGTTAGCCT
GAATTCCGATCTCAGCATGTTGCCGCCGAGCCTGCGTGGCTACGCGCCAGAAGTGACGGGGATCTCCCGTTCAGGCGGTA
AAGTGACCATCAGCCAGCAGGGACGCGTAATACACGAAACGCAGGTGGCCGCCGGGGCATTTCGTATTCAGGAACTGAAT
GATGCCATCTCTGGCACGCTCGACGTAAGGGTGGAAGAGCTGGACGGCAGCGTGCAGGTCTTTCAGGTCACGACGGCTTC
GGTTCCCTACCTGACGCGCCCGGGTGCGGTGCGCTACAAGCTTGCAGCGGGTAAACCCTCCGAGTGGGGGCACAGCATGA
TCGGGCCGATGTTCACCTCGGGAGAAATCTCCTGGGGCGTGGCCAACGGCTGGACGCTGTACGGCGGCTCGGTGATCGGC
GGTGACTATAATGCCCTGTCGGTGGGGATCGGGCGCGATCTCTTCATCCTCGGCGCGCTGGCCTTCGACGTAACGCAGTC
GCGGGCGGTATTGCCTTCTGAAGGAACGCTGTCCGGTACCTCTTACCGGGTGAGCTACTCAAAAACCTTCGACGAGTACG
ACAGCCAGGTCACCTTTGCCGGGTATCGTTTCTCCGAACGCGACTTTATGAGTATGTCGGAGTACCTCGATACCCGCTAC
GGCAGCGGCACGTCGCACAGCCCGAAAGAAAAATACACGGTGTCGTTTAACAAACGCTTCCGTGATGTCGGGCTGAGCGC
TTACCTCAACTACAGCCATCAGACCTACTGGAACAGCGCGGATAACGACCGCGTAAGCCTGTCGCTGTCGCGCTATGTCG
AGCTCGGTCCGTTCAAGAACATGAGCGTATCGCTTACGGCCTACCGCAGCGAGTACTACTCCCTGAAAGACGACGGGGCA
TACATTTCCGTGTCGTTGCCGATAGGTAACGGCACCTCGCTCAGCTATGGCGCCACAATTAACCGCACCGATAACACACA
TCGCGTGAGCTATTACGGCCGGGTGGATGAACACAATAGCTTCCAGGTTAGCAGCGGCCTTTCCCGCAGCGGCCCGACGG
CGTACGGCTACTACACCTGGCAGGGCGATAGCGCGCAGGTACAGACCAACGCCAGCTATCAGTCCGGCAGTTATACCGCG
CTGGGCATGAATGTGACCGGCGGTCTGACCCTGACCACCGAAGGGGGCGCAGCGCACCGCTCGAACGCGCGGGGCGGCAG
CCGCGTACTGGTGGATACCGCAGGCGTCAACGGCGTGCCCGTGAAGGGATTCGGCGCCTCGGTGAAAACCAACCGATTCG
GGAAGGCGGTGATTGGCGATGTGAACAGCTACTACCGCAATCCGATCCGCATTGACGTTGACAAGCTTGATGAAAACGCT
GACGTCACCCGATCGGTCTCACAGGCCACGCTCACCGAAGGGGCGATCGGCTATCGCCAGTTTGACGTGATTGCAGGTGG
TAAAGCGATGGCCTTTATCCGCAAGGCTGACGGGAGCTTCCCGCCATTTGGGGCCTCGGTGATGAACGAGAAAAACCAGG
AAACGGGGGTGGTGAATGACGAGGGAAGCGTCTGGCTAAGCGGCATTCAGCCAAACGGCAAAATGACCGTCAAATGGGAT
GGACAAGCCCGCTGCGTGGTAAACCTGCCGGCCGTGCTGCCAGCCGTGCTGGAGAATTTGCTTTTAACCTGTGCGCCGGA
ATAA

Protein sequence :
MKKTIRTFRRSTLSVLILALIVPVAKSWADDDIQFNTDVLDTQDKSNIDLSHFSRRGYVMPGDYTFSIMVNKDILREERI
VVYPEGENGRDSLICLTPEQLSRFNLKASVMDDLRWLRDGECLDKASLEGLDMRVDLAKDTLYLAIPQAWLEYTAPNWDP
PSRWDEGIPGVIADYNLNVQAQQNKTGSDSQNISGNGVLGANLGPWRARADWQTSWYKRDGKTDKDFAFSRYYLYRAIPS
LKAKLTVGEDYLSSDIFDTFRFSGVSLNSDLSMLPPSLRGYAPEVTGISRSGGKVTISQQGRVIHETQVAAGAFRIQELN
DAISGTLDVRVEELDGSVQVFQVTTASVPYLTRPGAVRYKLAAGKPSEWGHSMIGPMFTSGEISWGVANGWTLYGGSVIG
GDYNALSVGIGRDLFILGALAFDVTQSRAVLPSEGTLSGTSYRVSYSKTFDEYDSQVTFAGYRFSERDFMSMSEYLDTRY
GSGTSHSPKEKYTVSFNKRFRDVGLSAYLNYSHQTYWNSADNDRVSLSLSRYVELGPFKNMSVSLTAYRSEYYSLKDDGA
YISVSLPIGNGTSLSYGATINRTDNTHRVSYYGRVDEHNSFQVSSGLSRSGPTAYGYYTWQGDSAQVQTNASYQSGSYTA
LGMNVTGGLTLTTEGGAAHRSNARGGSRVLVDTAGVNGVPVKGFGASVKTNRFGKAVIGDVNSYYRNPIRIDVDKLDENA
DVTRSVSQATLTEGAIGYRQFDVIAGGKAMAFIRKADGSFPPFGASVMNEKNQETGVVNDEGSVWLSGIQPNGKMTVKWD
GQARCVVNLPAVLPAVLENLLLTCAPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 1e-163 45
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 3e-160 44
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 2e-159 44
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 1e-159 44
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 5e-160 44
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 5e-160 44
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 5e-160 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mrfC YP_003611616.1 fimbrial biogenesis outer membrane usher protein VFG1548 Protein 2e-160 44
mrfC YP_003611616.1 fimbrial biogenesis outer membrane usher protein VFG0884 Protein 2e-160 44
mrfC YP_003611616.1 fimbrial biogenesis outer membrane usher protein VFG0895 Protein 2e-160 44