Gene Information

Name : merA (ECL_A045)
Accession : YP_003602541.1
Strain :
Genome accession: NC_014107
Putative virulence/resistance : Resistance
Product : Mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 35499 - 37181 bp
Length : 1683 bp
Strand : +
Note : -

DNA sequence : 
ATGTATTTGAATATCACCGGAATGACCTGCGACTCGTGCGCGACACATGTCAAGGACGCCCTGGAGAAAGTGCCGGGCGT
GCTGTCGGCGCTCGTGTCCTACCCGAAAGGCTCCGCGCAACTCGCCACCGATCCCGGCACCTCGCCAGAGGCGCTGACCG
CCGCTGTGGCCGGCCTCGGCTACAAGGCCACACCCGCCGATGCCCCATCCACTTCAGCGCGGGGCAGACTGCTTGGCAAG
GCGCTGGGATGGCTGGGCGGTGGCGACAAGGCTGGTGGTGATGGGGACGGACTGCACGTCGCCGTTATTGGCAGCGGCGG
AGCCGCGATGGCGGCGGCGCTGAAGGCCGTCGAGCAAGGTGCGAACGTCACGCTGATCGAGCGCGGCACCATCGGCGGTA
CTTGCGTCAATGTCGGCTGCGTGCCGTCCAAGATCATGATCCGCGCTGCCCATATCGCCCATTTGCGCCGTGAAAGCCCA
TTCGACAGTGGCATCGCGGCGACTGTGCCTGCGATTGATCGCAGCAAACTACTGGCCCAGCAGCAGGCGCGCGTCGATGA
GCTGCGCCACGCCAAGTACGAAGGCATCCTGGACAGCAACCCGGCCATCACCGTGCTGCATGGTGAAGCGCGTTTCAAGG
ACGACCAGAGCCTTGCCGTCCGTTTAAACGATGGCGGCGAGCGTGTGGTGGCGTTCGACCGCTGCCTGGTCGCCACGGGT
GCCAGCCCGGCCGTGCCGCCGATTCCGGGCCTGAAAGAGTCACCCTACTGGACTTCCACCGAGGCCCTGGTCAGCGACAC
CATTCCCGAGCGCCTGGCCGTGATCGGCTCGTCTGTGGTGGCGCTGGAACTGGCGCAAGCCTTTGCCCGGCTGGGCAGCA
AAGTGACGATCCTGGCACGCAGCACGCTGTTCTTCCGCGAAGACCCGGCCATCGGCGAGGCCGTTACAGCCGCGTTCCGT
GCCGAAGGGATCAAGGTATTGGAATACACGCAAGCCAGCCAGGTCGCGCATGTGGACGGCGAATTCGTGCTGACCACCGG
GTACGGTGAAATACGCGCCGACCAGCTGCTGGTCGCCACTGGCAGGGCACCGAACACGCGCAGCCTGGCATTGGAAGCGG
CGGGAGTCGCTGCCAATGCGCAGGGGGCCATCGTCATCGACAAGGGCATGCGCACCAGTACGCCACACATTTATGCGGCT
GGCGACTGCACCGACCAGCCTCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACCCGTGCTGCGATCAACATGACTGGCGG
CGATGCGGCCCTGGACCTGACCGCAATGCCGGCCGTGGTGTTCACCGACCCGCAGGTCGCCACCGTGGGCTACAGCGAGG
CGGAAGCACATCACGACGGGATCGAGACCGACAGTCGCACCTTGACCTTGGACAACGTGCCGCGTGCGCTTGCCAACTTC
GACACACGCGGCTTCATCAAGCTGGTCATCGAGGAAGGTAGCGGACGGCTCATCGGCGTGCAAGCGGTGGCCCCGGAAGC
GGGTGAACTGATCCAGACGGCGGTGCTCGCCATTCGCAACCGTATGACCGTGCAGGAACTGGCCGACCAATTGTTCCCCT
ACCTGACCATGGTCGAAGGGCTGAAGCTCGCGGCGCAGACCTTCAGCAAGGACGTGAAGCAGCTTTCGTGCTGCGCCGGA
TGA

Protein sequence : 
MYLNITGMTCDSCATHVKDALEKVPGVLSALVSYPKGSAQLATDPGTSPEALTAAVAGLGYKATPADAPSTSARGRLLGK
ALGWLGGGDKAGGDGDGLHVAVIGSGGAAMAAALKAVEQGANVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESP
FDSGIAATVPAIDRSKLLAQQQARVDELRHAKYEGILDSNPAITVLHGEARFKDDQSLAVRLNDGGERVVAFDRCLVATG
ASPAVPPIPGLKESPYWTSTEALVSDTIPERLAVIGSSVVALELAQAFARLGSKVTILARSTLFFREDPAIGEAVTAAFR
AEGIKVLEYTQASQVAHVDGEFVLTTGYGEIRADQLLVATGRAPNTRSLALEAAGVAANAQGAIVIDKGMRTSTPHIYAA
GDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANF
DTRGFIKLVIEEGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 90
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 90
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 90
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 89
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 89
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 86
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 86
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 86
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 7e-178 77
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-77 41
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-77 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_003602541.1 Mercuric reductase BAC0652 Protein 0.0 89
merA YP_003602541.1 Mercuric reductase BAC0653 Protein 0.0 80
merA YP_003602541.1 Mercuric reductase BAC0650 Protein 2e-162 70
merA YP_003602541.1 Mercuric reductase BAC0224 Protein 3e-74 45
merA YP_003602541.1 Mercuric reductase BAC0651 Protein 1e-77 41