Gene Information

Name : clpE2 (LCRIS_01954)
Accession : YP_003602426.1
Strain : Lactobacillus crispatus ST1
Genome accession: NC_014106
Putative virulence/resistance : Virulence
Product : ATP-dependent clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1964865 - 1966991 bp
Length : 2127 bp
Strand : -
Note : -

DNA sequence :
ATGGCATACTTTGACAATGACTTTGATAACTTATTTAACGAATTGAACAGCTCATTCTTTAATGATGACTTTGGTAGCAG
AAGAAATAGCAAAGGCAGTTCAGGTTCAATTCCAATTAATTACTCCAGCAGCATGGGTGCTGCACCACAAACAATTCAAC
AGAACCCACAACAACCCAATGAAAAGCCAATTGGTGTTGACTTAGTTGAGGAAGCTAAGAACAATAAATTTGACCCAGTA
ATTGGTCGTGATGAACAGATCGATAACGTAATTGAAATTCTTTCAAGACGTAAGAAGAACAATCCTGTTTTAATCGGACC
TGCTGGTGTTGGTAAGACTTCTATTGTAGAAGGTTTAGCTGAAAGAATTGCTTCAGGCAATGTACCAGCTAAAATGGCTA
ACATGCATATCATTTCAGTAAACATTAATGACATGGTTGCTGGTTCAAGTCTTCGTGGTAGCTTTGAAGAAAGATTAAAG
AAGGTTATTGATAAGGCTAAGAGCGATCCTAACATTGTTTTATTCATCGATGAAATTCACAACATCGTTGGTGCTGGTTC
TACTGATTCAGAAAATAATAATGGGGATGCAGCTAACATCTTGAAGCCAGCTTTGGCAAGTGGTCAATTGAAGTTAATTG
GTGCTACTACTACTAGTGAATTCCAAAGAATTGAAAAAGACCCAGCTTTATCACGTAGATTCCAAGCTGTTCAGGTTCCA
GAACCTACAACTAAGGTTGCTGTTAAGATTTTGGAAGGCTTGAAGAAGAAGTACGAAGACTACCACCACGTAAAATACAG
TGACGACAGTCTTAAATTAGCTGTTGAATTATCAGAAAGATACATTCAAGGCCGTTACTTACCAGACAAGGCCATCGACT
TGATGGATGAAGCTGGTGCTAAAAAGGCATTGCTTGTACAACCAACTGATGAAAAGAGCTTAAAGAACCAAATCTCAGCT
CTTGAAGCTAAGAAGACTGAAGCTGCTAAGGCAGAGGATTACGACAAGGCTTCAGAAATTAAGAGTAAGATTGCTGAACT
TGAGAAACAACTTAAGAATGTAGATTCTAAGAATACTCCAGAAGTAACTGAAAAAGACATCTACGCAATTATTGAACAAA
AGACTAAGATCCCAATGAGTGAACTCCACGCTGATGAAGCTCAAAAGAACTTGGACTTAGCTAAGAAACTTAAGAAGAAT
GTTATTGATCAAGACAGAGCTATCGATGTAATTACTGACGCTATTGCTCGTAAGCAAATCTTCAAAGACAGCGACAGACC
TACTGGTTCATTCTTACTCACTGGACCTACTGGTGTTGGTAAGACTGAACTTGCTAAACAATTGGCAATTCAATTATTTG
GTAACAAGGAACACTTAATCCGTTTGGACATGAGTGAATACCAAGACGAAATGGCAGTTAACAAGTTGATCGGTTCAGCA
CCTGGCTATGTTGGCTACGGTGAAGGTGGTCAATTAACTGAAAAGGTTCGTCACCAACCATACTCATTGATTTTATTTGA
TGAAATTGAAAAGGCTAACCCACAAGTCTTCAACGCATTATTGCAAATTATGGATGACGGTCGTTTGACTGACGCACAAG
GTAGAACTGTTTCATTCAAGGATACTATCTTGATTATGACTTCAAACGCCGGCTTCTCAGACAAGTTGCTTGAAGATGGC
AAGGTTGACCAAGACAAGTTAATCTCAGCCCTTGAAAACTACTTCAGACCTGAATTCTTGAACCGGTTGGACGCAATCGT
TCCATTCAACTCACTTACTGAACAAGACATGGGCAAGATCATCAACATTTACTTGAAGAAGATGTCTCATGTTCTTGCTA
AGAAGGGTGTAACGGTAGAAGTTTCAGACGAAGCTAAGGCATTCTTGGCAGAAAAGGGCTACGACAAGAAGTTCGGTGCT
CGTCCACTTAGAAGAGTAGTTGAACAAAATCTTGAAACTCCAGCTGCTAAGTTGATCTTACAAAAGCCTGACACTAAGAA
GATCGAATTCACTGCAGATGACAAGCACTTGTACTTGAACGGTGAAGCAATCTTTGATATTTCTCCAAAAGTTGAAGAAA
AGGTTAAAGAAGACGAAGCTAAAACTGAAGACAAAAAAGAAGACTAA

Protein sequence :
MAYFDNDFDNLFNELNSSFFNDDFGSRRNSKGSSGSIPINYSSSMGAAPQTIQQNPQQPNEKPIGVDLVEEAKNNKFDPV
IGRDEQIDNVIEILSRRKKNNPVLIGPAGVGKTSIVEGLAERIASGNVPAKMANMHIISVNINDMVAGSSLRGSFEERLK
KVIDKAKSDPNIVLFIDEIHNIVGAGSTDSENNNGDAANILKPALASGQLKLIGATTTSEFQRIEKDPALSRRFQAVQVP
EPTTKVAVKILEGLKKKYEDYHHVKYSDDSLKLAVELSERYIQGRYLPDKAIDLMDEAGAKKALLVQPTDEKSLKNQISA
LEAKKTEAAKAEDYDKASEIKSKIAELEKQLKNVDSKNTPEVTEKDIYAIIEQKTKIPMSELHADEAQKNLDLAKKLKKN
VIDQDRAIDVITDAIARKQIFKDSDRPTGSFLLTGPTGVGKTELAKQLAIQLFGNKEHLIRLDMSEYQDEMAVNKLIGSA
PGYVGYGEGGQLTEKVRHQPYSLILFDEIEKANPQVFNALLQIMDDGRLTDAQGRTVSFKDTILIMTSNAGFSDKLLEDG
KVDQDKLISALENYFRPEFLNRLDAIVPFNSLTEQDMGKIINIYLKKMSHVLAKKGVTVEVSDEAKAFLAEKGYDKKFGA
RPLRRVVEQNLETPAAKLILQKPDTKKIEFTADDKHLYLNGEAIFDISPKVEEKVKEDEAKTEDKKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-128 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE2 YP_003602426.1 ATP-dependent clp protease, ATP-binding subunit VFG0080 Protein 3e-147 51
clpE2 YP_003602426.1 ATP-dependent clp protease, ATP-binding subunit VFG0079 Protein 2e-126 45