Gene Information

Name : pyk (LCRIS_01008)
Accession : YP_003601480.1
Strain : Lactobacillus crispatus ST1
Genome accession: NC_014106
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1016702 - 1018471 bp
Length : 1770 bp
Strand : +
Note : -

DNA sequence :
ATGAAGAAAACTAAGATTGTTAGTACTTTAGGGCCAGCTTCAAACGATATTGAAACTATTACTGCTTTAGCTAAGGCTGG
TGCAAACGTATTCCGTTTCAACTTCTCACACGGTGACCACCCAGAACACCTTGCTCGTATGAAGATGGTTCGTCAAGTGG
AAAAGGATACTGGTTTACTTCTTGGTATCGACCTTGACACTAAGGGTGCTGAAATCAGAACCACTGAACAAGAAGGTGGT
AAGTTCACTATTAATACTGGTGACATGATCCGTGTATCAATGGATGCCACTAAGAAGGGTAACAAGGACATGATTCACGT
TACCTACGACGGTTTATACGATGATACTCACGTTGGTGGTCACGTATTAATCGATGATGGTTTGGTTGACCTTTTGATCA
AGGAAAAGGACGACTCAAAGAGAGAACTTGTTTGTGAAGCTCAAAACACTGGTGTAATCGGTTCAAAGAAGGGTGTTAAC
GCTCCTGGTGTTGAAATTCGCCTTCCAGGTATTACTGAAAAGGATACTGATGACATTAAGTTTGGTTTGAACTATGGTAT
TAACTTCATTACTGCTTCATTTGCACGTAAGGCTCAAGATATCTTAGACATCCGTAAGCTTTGTGAAGAAGCAGGTGCAG
ACTACGTTAAGATCTTCCCAAAGATTGAATCTCAAGAAGGTATCGACAACGCAGACGAAATTTTGCAAGTTTCAGATGGT
TTAATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCATTTATGGAAGTTCCATTTGTACAAAAGAGCCTAATCCGCAA
GGCTAACGCACTTGGTAAGCCAGTTATTACTGCTACTCAAATGCTTGACTCAATGCAAGAAAACCCACGTCCAACTCGTG
CCGAAGTTTCAGACGTTGCTAACGCTGTTCTTGATGGTACTGACGCAACTATGCTTTCAGGTGAATCAGCAAATGGTCTT
TACCCAGTTAAGGCTGTTAAGGCTATGGCTGAAATTGACGAACGTACTGAAAAGCAAATGCTTAAGCGTAATACTTTAGC
TCTTCAAAGATTCGAAGCCTACAAGGGTTCAAACGTAACTGAAGCTATCGGTGAATCAGTTGTACGTACTGCTCAAGAAT
TAGGTGTTAAGACTATCATTACTGCAACTAACTCAGGTTACACTGCACGTATGATTTCTAAGTACCGTCCAAATGCTGAC
ATTATTGCTATGACCTTTGACGAAAAGATTCAACACTCATTGGGTATCGTTTGGGGTGTACAACCAGTATTGACTGAAAA
GCCTAAGTCAACTGATGACATGTTTGAAATGGCTGCTAAGGTAGCTAAGGAAAAGGGTTACGTAAAGGATGGCGACCTTG
TAATTATCGTTGCAGGTACTCCACTTGGTGACTCAGGTACAACTAACTTAATGAAGTTACAAATCATCGGTAACAAGTTA
GTTCAAGGCTTAGGTGTTGGTAACGGTTCAGTTATCGGCAAGGCTGTTGTAGCTAACTCAGCTGAAGAAGCAAACAGCAA
GGTTAAGGAAGGCGACATCTTAGTTGCTAAGACTACTGACCCAGACTACAACCCAGCTATCAAGAAGGCTTCAGGTTTAG
TTGTTGAAGCTTCAGGTTTAACTTCACATGCCGCAGTTATCGGTTTATCATTAGGTATCCCAGTTGTTGTTGGTGCTACT
GACGCTACTGACAAGATTTCTGATGGTTCAACTATTACTGTTGACGCTCGTCGTGGTGCTATCTACCAAGGCGAAATCTC
AAACCTTTAA

Protein sequence :
MKKTKIVSTLGPASNDIETITALAKAGANVFRFNFSHGDHPEHLARMKMVRQVEKDTGLLLGIDLDTKGAEIRTTEQEGG
KFTINTGDMIRVSMDATKKGNKDMIHVTYDGLYDDTHVGGHVLIDDGLVDLLIKEKDDSKRELVCEAQNTGVIGSKKGVN
APGVEIRLPGITEKDTDDIKFGLNYGINFITASFARKAQDILDIRKLCEEAGADYVKIFPKIESQEGIDNADEILQVSDG
LMVARGDMGVEIPFMEVPFVQKSLIRKANALGKPVITATQMLDSMQENPRPTRAEVSDVANAVLDGTDATMLSGESANGL
YPVKAVKAMAEIDERTEKQMLKRNTLALQRFEAYKGSNVTEAIGESVVRTAQELGVKTIITATNSGYTARMISKYRPNAD
IIAMTFDEKIQHSLGIVWGVQPVLTEKPKSTDDMFEMAAKVAKEKGYVKDGDLVIIVAGTPLGDSGTTNLMKLQIIGNKL
VQGLGVGNGSVIGKAVVANSAEEANSKVKEGDILVAKTTDPDYNPAIKKASGLVVEASGLTSHAAVIGLSLGIPVVVGAT
DATDKISDGSTITVDARRGAIYQGEISNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-73 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-74 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-74 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-73 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003601480.1 pyruvate kinase VFG0479 Protein 4e-74 46