Gene Information

Name : BMD_0863 (BMD_0863)
Accession : YP_003596075.1
Strain : Bacillus megaterium DSM 319
Genome accession: NC_014103
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 843880 - 845367 bp
Length : 1488 bp
Strand : +
Note : -

DNA sequence : 
ATGGATCGTACAGCCGTTAAAACGTTAACTTTGAATATGTACATAAACGGAGAGTGGAAAAAAGCAGAGAAGCAGCGTCC
TGCTGTTAATCCAGCTACAGGTGAAGTGATTGGATATGCTGCAGAAGGCAGCATAGAAGATATGAAAACAGCGATTGGAG
CAGCACGAGAAGCCTTTGACAGCGGAATTTGGTCTGAGACTTCTGCATCTGAAAGAGCAGCTATCTTATTTAAAATTGCC
GATAAGCTTGAAGAAGCGAAAGAAGAATTAGCAGCGCTAGAAACAATGGATAACGGAAAGCCCTATCGCGAAGCTGAGGC
TGATGTGGAAGATGCAGCTGCTTGTTTTAGGTATTACGCTGGATTAATTACAAAGCCAGACGGTCAAACGTACAGTGTTC
CGGCACCTATGCAAGCAATGGTTATAAAAGAACCAATTGGGGTGTGCGGATTGATTGTACCTTGGAATTATCCGCTGTTG
ATGAGCGTGTGGAAAATTGCACCTGCTTTAGCTGCAGGAAATACGATTGTATTTAAACCTTCTGAAGTGACACCGGTTAC
TCCTACAAAACTTTTTGAGATTTTAGAAAGCGTAGGATTGCCAAAAGGAGTAGCAAACCTTGTTATGGGAGCCGGAGATA
CTGTGGGAAATACGCTTATTCAAGATAAGCGTGTTGATAAGATTTCCTTTACAGGAGGAACGGTAACTGGAAAACACATT
ATGCGTCAAGCAGCAGAGAATGTAACGAAAGTCTCTTTAGAACTTGGAGGAAAGTCACCGAACATTATATTTGCTGACGC
TGATTTTGAAACAGCTGTAGATTATGCCTTATTTGGAATTTTTGCAGGGAGCGGCCAAATTTGCGCTGCAGGTTCTCGTA
TTTTAGTAGAAGAAAGCATCGCTGAGAGATTTCTCGAACGTTTTGCAGAGCGTGCTCAAAAAATTAAAGTAGGAAATGGA
ATGGATCAAGAGATTGAAATGGGCCCTCTTGTAAGTGAAGAACATATGAAAAAAGTATTAAAGTACATCGAAATTGGAAA
GCAAGAAGGCGCCCGCCTTGTATGCGGAGGCAATCGAATCACCAGCAGTGGATTGGAAAAAGGATTCTTTGTAGAACCTA
CGGTTTTTAGTAACGTTACGTCAAATATGAAAATTGTGCAAGATGAAATCTTTGGACCCGTTGTCGTTATTCAAACGTTT
AAAGACGAAAAAGAAGCTATTAAGCTTGCAAATGATACGGAATATGGTTTGGCAGGCAGTGTGTTTACAAACGACGGCGC
AAAAGCTCTTCGGGTGATTAAAAAGCTGCGTGCGGGCATCACTTGGGTAAACACATATCATTTTACATTTAACGAAGCGC
CTTGGGGCGGATATAAGCAGAGCGGAATTGGTCGAGGACTGGGCACGTTTGGATTGGAAGAATTTCAAGAAGTAAAACAA
ATTAATATTAATTTACAAGTAGAGCCAATCGGCTGGTTTAAAAATTAA

Protein sequence : 
MDRTAVKTLTLNMYINGEWKKAEKQRPAVNPATGEVIGYAAEGSIEDMKTAIGAAREAFDSGIWSETSASERAAILFKIA
DKLEEAKEELAALETMDNGKPYREAEADVEDAAACFRYYAGLITKPDGQTYSVPAPMQAMVIKEPIGVCGLIVPWNYPLL
MSVWKIAPALAAGNTIVFKPSEVTPVTPTKLFEILESVGLPKGVANLVMGAGDTVGNTLIQDKRVDKISFTGGTVTGKHI
MRQAAENVTKVSLELGGKSPNIIFADADFETAVDYALFGIFAGSGQICAAGSRILVEESIAERFLERFAERAQKIKVGNG
MDQEIEMGPLVSEEHMKKVLKYIEIGKQEGARLVCGGNRITSSGLEKGFFVEPTVFSNVTSNMKIVQDEIFGPVVVIQTF
KDEKEAIKLANDTEYGLAGSVFTNDGAKALRVIKKLRAGITWVNTYHFTFNEAPWGGYKQSGIGRGLGTFGLEEFQEVKQ
ININLQVEPIGWFKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-79 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-82 44
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-82 44
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-82 44
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-81 44
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-80 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BMD_0863 YP_003596075.1 betaine aldehyde dehydrogenase VFG0082 Protein 5e-80 45