Gene Information

Name : Btus_2192 (Btus_2192)
Accession : YP_003590013.1
Strain : Kyrpidia tusciae DSM 2912
Genome accession: NC_014098
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2200637 - 2202748 bp
Length : 2112 bp
Strand : -
Note : TIGRFAM: urease, alpha subunit; urease, beta subunit; KEGG: pjd:Pjdr2_4326 urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Urease beta subunit

DNA sequence :
TTGAAGCCCGGGGAAATGTTTCTGGGGCCAGATCCGGTTCGGATCAACGAAGGTCGGCGGACGGTGGTGGTGACGGTGGT
CCACCGGGGCGATCGACCGATCCAGGTGGGATCGCATTTTCATTTTTATGAGGTCAACGAGGCTCTCGATTTTGACCGGG
AGAAAGCTTGGGGCATGCGGCTTAACATCCCCGCCGGCACTGCCGTCCGCTTCGAGCCGGGGGAAGAGAAGACGGTGGTT
TTGGTGGAGATCGGCGGGGCCCGGCGGGTGTATGGGCACCGGGGGCTCGCCGAGGGTTCGGTTGAATCCCCAGAGGCGGA
TCCGAGAGGGGCCCCGGGAGAAACCAGGGAGGCCGGACAGAGGGTGGAGGATGTGGTTGCCCAGGCGGCCGGGCGGGGAC
TGGAGATGACCCGGGAAGCCTACGCCGGGATGTTCGGGCCGACCACCGGGGATCGGGTGCGGTTGGCGGACACCGAGCTG
ATCATCGAGGTCGAACGGGATTTTACTGTTTACGGGGATGAGTGCAAGTTCGGCGGGGGGAAGGTGCTGCGGGATGGAAT
GGGCCAATCCTCCCGGGCCACTCGCCGGGACGGCGTGTTGGACCTGGTGATCACCGGCGCCCTGGTGGTGGATCACTGGG
GCATTGTCAAAGGAGACATCGGGGTCCGGGACGGCCGGATCGTTGGGATCGGAAAGGCGGGCAATCCCGAGACCATGGAT
GGGGTGCGTCCGGACATGGTGATCGGGGCGGCCACTGAAGTGGTGGCGGGGGAGGGGTGCATCGTGACGGCGGGGGGCAT
CGACAGTCACATTCATTTTATCAGCCCCCAGCAGGTGGAAACGGCGCTGGGGTCGGGGATCACCACGATGATCGGCGGCG
GGACCGGGCCGGCCACCGGCACCAACGCCACCACCTGTACGCCCGGAGCGTGGAATCTTCAGCGCATGCTCGAGGCCTCC
GAGGGATTTCCGGTCAACCTCGGATTTCTCGGAAAGGGAAATGCCACCGGGGAGGAGGCGCTGGCGGAGCAGATCGCGGC
CGGTGCTTGCGGGTTAAAATTGCACGAGGACTGGGGGGCGACGCCGGCGGCCATCGATGCTTGCCTGCGGGTGGCCGACC
GATTTGACGTGCAGGTGGCGATCCACACCGATACGTTGAATGAGGCGGGTTTTGTGGAGACGACGATCGCGGCCTTTAAG
GGACGGACGATCCACACGTATCACACCGAAGGGGCGGGGGGCGGCCACGCTCCGGACATCCTGCGGCTGGCCGGGGAGGC
CAATGTCCTGCCCTCGTCCACGAATCCGACCCGCCCTTTTACCGTCAACACCATCGAGGAGCACTTGGACATGTTGATGG
TATGCCATCACCTGGACAGCCGGATTCCCGAGGATGTGGCCTTTGCCGATTCTCGCATTCGTCCGGAGACGATTGCCGCC
GAGGATATCCTTCACGACCTGGGGGCGCTGAGCATGATGAGTTCGGACTCCCAGGCCATGGGGCGGGTGGGGGAAGTGGT
CCTCCGCACGTGGCAGACGGCGGACAAGATGAAACGCCAGCGGGGCAGGCTCCCGGAGGAGCGAGGGGATAACGATAACG
AGCGGGTCAAGCGCTACATTGCAAAATACACCATCAATCCGGCGCTGACCCACGGGATCGCCGAGTACGTGGGCTCGGTG
GAACCGGGCAAATGGGCGGATTTGGTGATCTGGAAACCCGCTTTTTTCGGAGTGCGACCGGAGATGGTGATCAAGGGCGG
CATGATCGTCTATGCGGCCATGGGGGAAGCGAACGCTTCGATCCCCACGCCCCAGCCGGTTTTTGGCCGCTCGATGTTCG
CCGCCTTCGGGGCGGCGGCCTGGGGCCGTTGTTTCACCTTTGTGTCCCAGGCAGCCCACGAGTCGGGGATCGCAGATCGG
CTGGGTTTGCGCCGGCGGGTGGTTCCGGTGAAAAACTGCCGGAAAATCGGAAAAAAGGATATGGTCAACAACTTCGCCAC
TCCCCGGATCGAGATCGATCCAGAGACGTACCAAGTTCGGGTGGACGGGGTGTTGGCGACTTGTGAGCCGGCCAAGGTGG
TGCCCTTGGGTCGGCGGTATTTTCTCTTTTGA

Protein sequence :
MKPGEMFLGPDPVRINEGRRTVVVTVVHRGDRPIQVGSHFHFYEVNEALDFDREKAWGMRLNIPAGTAVRFEPGEEKTVV
LVEIGGARRVYGHRGLAEGSVESPEADPRGAPGETREAGQRVEDVVAQAAGRGLEMTREAYAGMFGPTTGDRVRLADTEL
IIEVERDFTVYGDECKFGGGKVLRDGMGQSSRATRRDGVLDLVITGALVVDHWGIVKGDIGVRDGRIVGIGKAGNPETMD
GVRPDMVIGAATEVVAGEGCIVTAGGIDSHIHFISPQQVETALGSGITTMIGGGTGPATGTNATTCTPGAWNLQRMLEAS
EGFPVNLGFLGKGNATGEEALAEQIAAGACGLKLHEDWGATPAAIDACLRVADRFDVQVAIHTDTLNEAGFVETTIAAFK
GRTIHTYHTEGAGGGHAPDILRLAGEANVLPSSTNPTRPFTVNTIEEHLDMLMVCHHLDSRIPEDVAFADSRIRPETIAA
EDILHDLGALSMMSSDSQAMGRVGEVVLRTWQTADKMKRQRGRLPEERGDNDNERVKRYIAKYTINPALTHGIAEYVGSV
EPGKWADLVIWKPAFFGVRPEMVIKGGMIVYAAMGEANASIPTPQPVFGRSMFAAFGAAAWGRCFTFVSQAAHESGIADR
LGLRRRVVPVKNCRKIGKKDMVNNFATPRIEIDPETYQVRVDGVLATCEPAKVVPLGRRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-158 67
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-158 67
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-156 65
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-157 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 5e-157 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-157 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Btus_2192 YP_003590013.1 urease subunit alpha VFG0270 Protein 2e-162 66