Gene Information

Name : Btus_2090 (Btus_2090)
Accession : YP_003589919.1
Strain : Kyrpidia tusciae DSM 2912
Genome accession: NC_014098
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2093854 - 2096082 bp
Length : 2229 bp
Strand : -
Note : KEGG: gwc:GWCH70_0549 heavy metal translocating P- type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain prote

DNA sequence :
ATGGCTGTGCCGAATGACCGCTTGCTGGATCGGAACCCCGGGATTGCGGAGAAACCTGGCCAACCCGCAAATCGCCCGGA
TCCGGTCCGGCCCCAGGAACATGTGTATCGACTGGCGAATTTAAGCTGCGCCGATTGTGCCGCGAAATTTGAAGACAAAG
TCAAACGGGCGTCCGGGGTAGTGGATGCCCGGGTGCTTTTTGGATCCTCCCAATTGATCGTGGTCGGGCAACCACTGAGT
GTGGATGAACTGGAGCGCCTGGGGGCCTTTGACAACATCAAGGTGGTCGCCGGGGCAGACGCCGCCGCTCCGGAGCTGGC
CGGGCGGGGCGTCCTCAGTGCAGAACGGTCTCCTTGGTGGGCCGAACCCCGGGTGGGGCGGGCGGCGATGGCCTTGCTCC
TTATCGCAGCCGCCCATGTCCTGCAGGGGAGCGGGGCGGCACCCGTTATCGCGACGACTGCTTACGCCGCGGCGGTTCTC
CTGGGAGGCTGGGGGACCTTCAAAAAAGGGATTCCGGGCATTTTCCGGCTGGATTTTCACATGAATGCCCTGATGACCGT
GTCCGTGGCCGGCGCCATGGCCATCGGGTACTGGAGTGAGGCCGCCACCGTTGCTTTCCTGTTCGGGGTCAGTGAAGCGT
TGGAGAACCACGCCATGGACCGGGCCCGCCGCTCGATCCGCTCCCTGGCGGAGATGGCCCCCACCCGGGCGATGGTTCGC
CGGGAGGGAAAGGAAATGATTGTGCCCGTCGAGGCCATCCGGGTCGGCGACGTGATGATCGTGCGGCCAGGGGAAAAAAT
TGCCCTGGACGGAAGGGTGATCCGGGGGCGCACCGAGGTGAACCAAGCGGCCATTACCGGCGAGTCGCTCCCCGTGGCCA
AAGAAGCGGGCGATGCGGTCTTTGCCGGGTCGCTGAACCATTCGGGCGCCATCGAGGTCGAAGTGACCAGCCGGGCCGGG
GACAGCACCCTGGCCAGGGTCATCGCCCTGGTGGAAAGGGCCGAGGCCGAGCGGGCCCCGACCCAGGAGTTTGTCAACCG
CTTCGCCAGAATCTACACACCGGCGGTTACGGTTTTGGCGGTGGGCATGGCCCTCATTCCGCCTCTCGTCTGGGGCGCCG
CTTGGCTCCCGTCAATCTATGAAGCATTGGCGCTGCTCATGGTGGCCTGCCCCTGTGCCCTGGTGGTTTCGACCCCGGTG
GCGGTGGTGACGGCGATGGGCGTTGCGGCCCGCAGTGGCGTGCTGATCAAGGGTGGGATTCATTTGGAAAATATCGGCCG
TCTTCGGGCGATCGCTTTTGACAAAACCGGCACGCTCACCTCGGGGGAGCCGGTGGTCACGGACGTGATCGGGTTCCAAA
CTATGACTGAAGAAGACATCCTCCGGGTGGCGGCGGGCATCGAGCGTTATTCGGAGCATCCGTTGGCCGGGGCGATCCTG
CGGGCAGCCGCAGACCGCGGCCTCACTCCCGGGGAAGTGGAGGATTTTGAGAGCTTTCCCGGACGGGGGGCCCGGGGCAC
CGTGGGCGGCACAGAGTACTGGATCGGAAGTCCCCGTTGGTTCAGGGAGCGCGGGGTGAATCTGGAGTCTGTGAACAACC
GAATTGGCGGTTTTCAGGAGGAGGGGAAAACGCTGGTGCTTCTCGGGCGAAGGGACACCGTGACCGCCTTGATTGCCGTG
GCCGACCGGGTGCGGCCTTCGGCCCGGGAGGTGGTCGCGAACCTCAAAATGGCCGGGATCGGGCCCACGGTTCTGTTGAC
CGGCGACAATCCGGCAACCGCCCGGGCGATCGGCCGGACCGTGGGTGTGGACGAGGTGCGGGCCGGGTTGCTCCCCGAGG
ACAAGGTCCGAGCCGTTTCCGAACTAAGGCAGCGGTACGGTCGGGTGGGGATGGTGGGCGACGGGGTGAATGACGCCCCG
GCCCTGGCCGCAGCCACCACCGGAATCGCCATGGGGACTTCGGGGACCGATCTCGCACTGGAGGCCGCAGATGTCGCTTT
GATGAACGATGATCTGTCGAAAGTTCCCTTCGCCGTCCGCTTGGGTCGAGCCACCTTGCGGATCATCCAACAAAATATTT
TTATCGCCCTTTTCATGAAGACGGCGGCCTTACTGCTGGCATTCCCCGGCTGGCTCACCTTGTGGCTCGCCATCGTCGGC
GACATGGGCGCCACCCTCCTGGTCACCGCCAACGCCCTGCGCCTGTTGCGGGTGCGACCCCGAAGTTGA

Protein sequence :
MAVPNDRLLDRNPGIAEKPGQPANRPDPVRPQEHVYRLANLSCADCAAKFEDKVKRASGVVDARVLFGSSQLIVVGQPLS
VDELERLGAFDNIKVVAGADAAAPELAGRGVLSAERSPWWAEPRVGRAAMALLLIAAAHVLQGSGAAPVIATTAYAAAVL
LGGWGTFKKGIPGIFRLDFHMNALMTVSVAGAMAIGYWSEAATVAFLFGVSEALENHAMDRARRSIRSLAEMAPTRAMVR
REGKEMIVPVEAIRVGDVMIVRPGEKIALDGRVIRGRTEVNQAAITGESLPVAKEAGDAVFAGSLNHSGAIEVEVTSRAG
DSTLARVIALVERAEAERAPTQEFVNRFARIYTPAVTVLAVGMALIPPLVWGAAWLPSIYEALALLMVACPCALVVSTPV
AVVTAMGVAARSGVLIKGGIHLENIGRLRAIAFDKTGTLTSGEPVVTDVIGFQTMTEEDILRVAAGIERYSEHPLAGAIL
RAAADRGLTPGEVEDFESFPGRGARGTVGGTEYWIGSPRWFRERGVNLESVNNRIGGFQEEGKTLVLLGRRDTVTALIAV
ADRVRPSAREVVANLKMAGIGPTVLLTGDNPATARAIGRTVGVDEVRAGLLPEDKVRAVSELRQRYGRVGMVGDGVNDAP
ALAAATTGIAMGTSGTDLALEAADVALMNDDLSKVPFAVRLGRATLRIIQQNIFIALFMKTAALLLAFPGWLTLWLAIVG
DMGATLLVTANALRLLRVRPRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-145 53
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-156 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-156 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Btus_2090 YP_003589919.1 heavy metal translocating P-type ATPase BAC0298 Protein 3e-112 51
Btus_2090 YP_003589919.1 heavy metal translocating P-type ATPase BAC0124 Protein 7e-87 45
Btus_2090 YP_003589919.1 heavy metal translocating P-type ATPase BAC0100 Protein 5e-68 44
Btus_2090 YP_003589919.1 heavy metal translocating P-type ATPase BAC0461 Protein 5e-78 42