Gene Information

Name : leuS (HMPREF0675_3951)
Accession : YP_003581118.1
Strain : Propionibacterium acnes SK137
Genome accession: NC_014039
Putative virulence/resistance : Unknown
Product : leucine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 971032 - 973512 bp
Length : 2481 bp
Strand : +
Note : identified by match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396

DNA sequence :
GTGAGCGACCAGGTGCGCGAGACAACGGGCTACGACGCAGTCGCAGCCCAAGAGAAGTGGTCCAAGTATTGGGAGGAGCA
CCGCACCTTCGCCTCCCTTGATGACGGCTCCAGGGAGCGTCGCTACGTGCTTGACATGTTCGCCTACCCCTCCGGTGACC
TTCACATGGGACATGCTGAGGCGTTCGCCATTGGCGATGTGCTGGCCCGTTACTGGCGTCTGCGTGGATTCGACGTGTTG
CACCCGGTGGGCTGGGACTCCTTCGGTCTGCCGGCTGAGAACGCCGCGATCAAGCACGGGACCCATCCTGCGGAATGGAC
CTACCGCAATATCGACACTCAGGCGGCCTCTTTTAAGCGGTACGCGGTTTCCTTCGACTGGTCGATGAGGCTGCACACCT
CCGATGAGGAGTACTACCGCTGGACCCAGTGGCTGTTTAACCGTTTCTTCGAAAAGGGACTGGCCTACCGTAAGGACTCC
TGGGCTAACTGGTGCCCCAACGACCAGACGGTGCTCGCCAACGAGCAGGTCAAGGATGGGTGTTGCGAGCGTTGTGGTGC
TGTCGTCACCAAGCGTCAGCTCAACCAGTGGTATTTCCGCATCACTGACTACGCTCAGCGTCTGCTCGACGATATGGACC
AGATCGAGGGTAAATGGCCCGAGCGTGTGCTGTCGATGCAGCGCAACTGGATCGGTCGTTCCGAAGGCGCCTACGTTGAT
TTCACGATTGATGGTCGCAAGGAGCCAGTGAGGGTTTTCACCACCCGTCCGGACACCCTGTACGGAGCTACCTTCATGGT
GGTGGCTCCTGACTCGGCCCTGGCCCAGGAGATCGTCTCCGATGAGGCCCGGCCAGCCTTTGAAACCTACCTCGATGAGG
TCAAGAAGAAGTCCGAAATTGAGCGGCAAGCCACCGATCACGAGAAGACCGGGGTGCCCCTCGGGGTCGAGGCGACTAAC
CCTGTCAATGGTGCCAAGGTTCCGGTGTGGGCTGGTGACTATGTGCTGGCGGACTACGGGACGGGTGCCATCATGGCTGT
GCCCGCCCATGACCAGCGTGACCTCGACTTCGCCCGCACATATGGCATTGACGTCATCCCGGTCATCGACACTGGCGAGG
CTGATCCTCGCGAGTCTGGGGTCGCTACGACGGGTGATGGCGCTTACCAAAACTCCGGATTCCTCGATGGCATCGCCACT
AAGACTGAGGCCATCGCGACAATGTGTGAGTTCCTTGGCAAGAAGGGGATCGGTGAGCCGACAATCACCTATCGGCTGCG
CGACTGGCTGCTAAGCCGTCAGCGTTTCTGGGGATGCCCCATCCCGATCATCCATTGTGAGTCCTGCGGCGACGTCCCGG
TCCCTGACGATCAGCTGCCAGTCAAGCTGCCCGATCTCCGCGGCGCCGAGCTTGCCCCTAAGGGTACGTCACCGCTGGCT
GGTGAAGAGGCCAGCGAATGGCGTTCGGTGGCCTGCCCGTCGTGTGGGGGAGCTGCCCAGCGTGACACCGACACCATGGA
CACCTTCGTGGACTCGTCGTGGTATTTCATGCGCTATTGCTGTCCGCACTATGACAAGGGCCCGTTTGACGTGGAGGCAG
TTCGTCGTTGGATGCCGGTAGCCCAGTACATCGGTGGCGTTGAGCATGCCACTATGCACTTGCTGTACTCCCGATTCTTC
ACCAAGGTGCTGCATGACCTCGGCATGGTCGACTTCACTGAACCGTTCCAGCGGCTCATGAACCAGGGTCAGGTCATCAA
TGAAGGCCGGGCAATGTCGAAGTCGCTGGGCAATGGCGTGGACCTCGGCAAGCAGATCGACGAGTTCGGTGTCGACGCAG
TACGTACCACCGTTATCTTCGCCGGTCCGCCAGATGAGGACATTGATTGGGCCGACGTCTCACCGGCCTCGACTCTAAAG
TTTTTGCAGCGTGCCTGGCGCGTGGCCTCTGAGGTCACGAGCGATCCTGACGCTGACCTGACACAAGGCGACTCCACCCT
GCGTCGGGTTACCCATCGCAGCATCGCCGACATCACCGAGTTGCTGGAGGGCGGGCGTTACAACGTCGTTGTGGCGCGGA
TCATGGAACTGGTCAATGCCACCCGTAAGGCCATTGATTCGGGGTGCGGCCCGGCTGATCCTGCAGTGCGCGAGGCTGTC
ACCTTTACTGCCCAGGCGCTATCTTTAGTGGCCCCGTACTTGGCTGAGGAGATGTGGGAGATGCTCGGCTTGGAGCCCTC
CGTTGCCAACTCTCATTGGCCCACTGCTGACGAGAAGCTGCTGGTAGCCGACAAGGTGACCATGGTCGTCCAGGTGACGG
GCAAGGTACGCGCTAAGCTCACAGTGAGCCCCGATATCACCGAGGCCGAGGCCCGCGAGGTGGCTTTAGCCGACGTTAAT
GTGCAGCGGTTTACTGAAGGCAAGGAGATCGTCAAGATCATTGCCAAGCTGCCGAAGATGATATCAATCGTCGCGAAATA
A

Protein sequence :
MSDQVRETTGYDAVAAQEKWSKYWEEHRTFASLDDGSRERRYVLDMFAYPSGDLHMGHAEAFAIGDVLARYWRLRGFDVL
HPVGWDSFGLPAENAAIKHGTHPAEWTYRNIDTQAASFKRYAVSFDWSMRLHTSDEEYYRWTQWLFNRFFEKGLAYRKDS
WANWCPNDQTVLANEQVKDGCCERCGAVVTKRQLNQWYFRITDYAQRLLDDMDQIEGKWPERVLSMQRNWIGRSEGAYVD
FTIDGRKEPVRVFTTRPDTLYGATFMVVAPDSALAQEIVSDEARPAFETYLDEVKKKSEIERQATDHEKTGVPLGVEATN
PVNGAKVPVWAGDYVLADYGTGAIMAVPAHDQRDLDFARTYGIDVIPVIDTGEADPRESGVATTGDGAYQNSGFLDGIAT
KTEAIATMCEFLGKKGIGEPTITYRLRDWLLSRQRFWGCPIPIIHCESCGDVPVPDDQLPVKLPDLRGAELAPKGTSPLA
GEEASEWRSVACPSCGGAAQRDTDTMDTFVDSSWYFMRYCCPHYDKGPFDVEAVRRWMPVAQYIGGVEHATMHLLYSRFF
TKVLHDLGMVDFTEPFQRLMNQGQVINEGRAMSKSLGNGVDLGKQIDEFGVDAVRTTVIFAGPPDEDIDWADVSPASTLK
FLQRAWRVASEVTSDPDADLTQGDSTLRRVTHRSIADITELLEGGRYNVVVARIMELVNATRKAIDSGCGPADPAVREAV
TFTAQALSLVAPYLAEEMWEMLGLEPSVANSHWPTADEKLLVADKVTMVVQVTGKVRAKLTVSPDITEAEAREVALADVN
VQRFTEGKEIVKIIAKLPKMISIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-157 42