Gene Information

Name : HMPREF0675_3651 (HMPREF0675_3651)
Accession : YP_003580823.1
Strain : Propionibacterium acnes SK137
Genome accession: NC_014039
Putative virulence/resistance : Virulence
Product : Thiol peroxidase, Tpx-type
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.15
Position : 669027 - 669530 bp
Length : 504 bp
Strand : +
Note : identified by match to protein family HMM PF00578; match to protein family HMM PF08534

DNA sequence :
ATGGCTACTACCGCTTTCATGGGAAAACCCCTTAACACCGTCGGGGACCTTCCTCAGGTCGGTTCCTTGTTGCCGTCGTT
CGCTCTCGTCAAGAGTGACTTGTCGGAGCTGAGAAGCGATGAGTTGAAGGGCAAGAAGCTCGTCCTCAACATTTTCCCGA
GTGTGGACACCGGAGTGTGTGCAACGAGTGTGCGCACCTTCAACGAGAAAGCCGCTGGACTCGACGACACCATCGTCTTA
TGTGTTTCTCGTGACCTTCCATTCGCCCAGGCTCGCTTCTGCGGTGCGGAGGGCATCAAGAACGTCGTTGTCGCCTCGGC
CTTCCGCTCCCATTTTGGTAAGGACCTTGGCGTTACCCTCGCCGATGGCCCGATGCAGCATCTGCTCGCGCGCGCCATCA
TCGTCGTGAACGCTGAGGGAAAGGTTACCTACACCCAGCTCGTCGATGAGATCACTACCGAGCCGGATTACGACGCTGCC
CTCGAGGCTGCGTCCAAGGCCTGA

Protein sequence :
MATTAFMGKPLNTVGDLPQVGSLLPSFALVKSDLSELRSDELKGKKLVLNIFPSVDTGVCATSVRTFNEKAAGLDDTIVL
CVSRDLPFAQARFCGAEGIKNVVVASAFRSHFGKDLGVTLADGPMQHLLARAIIVVNAEGKVTYTQLVDEITTEPDYDAA
LEAASKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 7e-34 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 4e-34 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 5e-34 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-34 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF0675_3651 YP_003580823.1 Thiol peroxidase, Tpx-type VFG0087 Protein 1e-34 47