Gene Information

Name : hemC (HMPREF0675_3347)
Accession : YP_003580532.1
Strain : Propionibacterium acnes SK137
Genome accession: NC_014039
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 375917 - 377017 bp
Length : 1101 bp
Strand : -
Note : identified by match to protein family HMM PF01379; match to protein family HMM PF03900; match to protein family HMM TIGR00212

DNA sequence :
TTGCCGCTCTGGTGCCGCAGGCCCGCCGAACTGTCCGTCAACTTGTCTGATTGCAGGCTGGAATCGGCGTCGGTACTGAG
TGCCACAATAGGCAATATGTCTGCGATCCGTCTGGGAACCCGTGCCAGCACTCTGGCCACTACTCAATCAGAGATGGTTG
CGGGGCTGCTCAGGTCGGAGGGGCTGGACGTCAATCTGACGACGATCACTACTCACGGGGACACCTCGACGGCCTCGTTA
GCGGCCATGGGAGGAATCGGGGTGTTCGCCTCGGCGATCCGTGCGGCCCTCCTCGAGGGAGAAGCCGACATTGCCGTCCA
CTCCTTCAAAGATCTACCGACAGGACGTCCGTTAGGACTGGCGATCGGTGCCGTTCCAGCTCGAGCGGACCCGCGTGACG
CTTTGGTGGCCCGCGATGGGCTCACCCTTCACGACCTCCCGCAAGAAGCTAGCGTCGGGACGGGCTCGCCACGTCGGGCC
GCACAGTTGTTGGCGGTTAGACCGGACCTGACGATCGTCGATATCCGTGGAAATGTCGACACCCGGCTGGGTCGCGTCAA
AGGACTCGGCCGCTACGCCAAAAACGGTGGCAAGGAGGACCTCGACGCCGTCGTGCTCGCAGCCTCCGGACTAGCTCGAC
TAGGTCATAGCGGCGCCGTCACTGAGTTCCTCGACCCGTCGGTAGTACTGCCTGCCCCTGCTCAGGGAGCGCTAGCCGTC
GAATGCCGGACCGCTGATTCACGTCATGGCAAGCTCGCCAAAGCGCTGGCACGGATTGACGACCGCAGAACCAGGCTGGC
CGCCACCGCCGAACGTGCGGTGCTCTCCCATCTAGAGGCGGGGTGCGCTGCCCCCATCGGAGCATTAGCTCAACTCAAGC
CTGTTTCGGGAAAATCCCTACAAGTGTTAACCCTGGATGTTGTAGTGGCTGCTGTCGACGGTTCCCGCACCGTTCGGGAA
CAGGTCAGCGTCGAATTACCCGCGGAGGTCGAACCAGCGCTGGCGGCGGCACATACGCTGGGGGTGACGGCTGCCGAAGA
GTTACTGGACGATGGTGCCGCCGACGTTGCAGATCTCAAAGCTTCAGGAAGCACTCGATGA

Protein sequence :
MPLWCRRPAELSVNLSDCRLESASVLSATIGNMSAIRLGTRASTLATTQSEMVAGLLRSEGLDVNLTTITTHGDTSTASL
AAMGGIGVFASAIRAALLEGEADIAVHSFKDLPTGRPLGLAIGAVPARADPRDALVARDGLTLHDLPQEASVGTGSPRRA
AQLLAVRPDLTIVDIRGNVDTRLGRVKGLGRYAKNGGKEDLDAVVLAASGLARLGHSGAVTEFLDPSVVLPAPAQGALAV
ECRTADSRHGKLAKALARIDDRRTRLAATAERAVLSHLEAGCAAPIGALAQLKPVSGKSLQVLTLDVVVAAVDGSRTVRE
QVSVELPAEVEPALAAAHTLGVTAAEELLDDGAADVADLKASGSTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-33 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-33 41