Gene Information

Name : tkt (HMPREF0675_5396)
Accession : YP_003582508.1
Strain : Propionibacterium acnes SK137
Genome accession: NC_014039
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2451703 - 2453766 bp
Length : 2064 bp
Strand : -
Note : identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
GTGGCAACCGAACTGACGTGGACCGACACCGATAGGCTCGCTGTCGACACCGCTCGAGTGCTGGCGGCCGATGCCGTCGA
GAAGACTGGTAACGGTCACCCCGGCACCGCTATTTCCCTAGCGCCGCTGGGCTACCTGCTTTACCACAAGGTCATGTCTA
TCGATCCGTCGGACCCGAATTGGCTCGGACGCGATCGCTTCATCATGTCGGCAGGACATTCCTCGCTGACCCAGTACACC
CAGTTATACCTAGCAGGGCTGGGACTCGAGCTGTCCGACCTGGAGTCCCTGCGTACCTGGGGATCCCTGACGCCCGGCCA
CCCCGAATATGGCTTGACGAAGTTCGTCGAGACCACCACCGGCCCGCTCGGCGCCGGTGTTGCCAACGCCGTCGGCATGG
CCATGGCAGCTCGTCGTGAACGCGGCCTGCTCGACCCGGACGCCGCTCCCGGTACGAGCCTCTTCGACCACTACATTTAC
GCCATTGCCGGTGACGGCTGTATGCAGGAAGGCATTGCATCTGAGGCTTCGTCTCTGGCGGGGACCCAGGAGCTGGGCAA
CCTCATCATGTTCTACGACGACAACCGGATCACCATCGAAGGTGATACCGCCATCGCCTTCTCTGAGAACGTCGAGGCCC
GCTATGAGGCCTACGGTTGGCATGTCCAGCACGTCGATTTCACCAACGGCGGAACGACCTACGAGGAGAATGTCGAAGCC
CTCATGGAGGCCATCGACAACGCCAAGACTGTTACCGACAAGCCGTCTTTCATCCGTCTCACCACCGTCATTGGTTGGCC
GATTCCGAAGCTCGCCGGTCTGGCCCAGGTACACGGTGCGAAGATTGGCGCTGAGGGGGTCAGTGCCCTCAAGGAGAAGC
TTGGCTTTGAAGACAAGCCGTTTGCCATCGACCTTGAGATGGTGCAACAGGTCCGCGCTGCTTTCGCTGAGCGCGGCAAG
GGTCTGCGCGAGGTCTGGGACGAGAAGTTCGCCGCCTGGCATGACGCCAACCCAGACGGCGCTGCCCTGCTCGAGCGGAT
GCTCGCCCACAAGCTGCCCGACGACCTCGACATTCCCACTTTTGAGCCGGGCAAGATGAGCACCCGTAAGGCTTCGGGAG
CGGTCCTGAGCGCTCTGGGTCCGCAGCTTCCCGAGCTGTGGGGCGGATCGGCCGACCTCGCCGGGTCGAACAACACGACC
ATGAAGGGGGCCGACTCCTTCCTGCCTGAAGATCGCTGCTCCGAGAAAGATCCAGGTGGTCCTTACGGGCGTACTATCCA
CTTCGGTGTTCGCGAGCACGCCATGGGTGGCATCCTCAACGGCATCACCTTGGCGGGCCTGACCCGCTGCTACGGCGGAA
CCTTCTTTGTCTTCTCCGATTACATGCGTCCGTCGGTGCGTCTTGCGGCCCTCATGAAGATCCCGTCGATCTTCGTGTGG
ACCCACGATTCTATCGGCGTTGGTGAAGATGGACCCACCCACCAGCCAGTCGAGCACCTAGCCTCCTACCGAGCCATCCC
GGGACTCGACATCGTCCGTCCCGCCGACGCCAACGAGACCGCCGTGGCATGGCGCACCATCGTGGAGCACACCGACCGTC
CCGCCGGCCTAGTGCTGTCGCGTCAGGACCTGCCGACGATTGACCGCAGCAAATACGCCTCTGCCGAAGGCGTCGCCAGG
GGTGCCTACGTGGTTTGCGAGGCTAGCGCCGAGCCCAAAGTCATCCTCATCGGTACTGGGTCCGAGCTGTCGGTGGCCCT
CGAAGCACGCGAGAAGCTTGAGGCCGACGGGATCGCGACCCGCGTCGTCTCGATGCCGTGCCAAGAGTGGTTCGACGAGC
AGGACGAGGAGTACCGCGAGTCGGTGCTACCCAGCTCAGTGACTGCCCGAGTGAGCGTCGAGGCCGGCATCGCCATGGGC
TGGGCAAAGTATGTCGGCTGCAAGGGCGCCTCGGTGTCCCTCGAGCACTTCGGCGCCTCGGCCTCTGGGGCGCTGCTGTT
CGAGAAGTTCGGATTCACCGCTGACCACGTCGCGGAGGTCGCTCACACCGTGTTCATGGAGTGA

Protein sequence :
MATELTWTDTDRLAVDTARVLAADAVEKTGNGHPGTAISLAPLGYLLYHKVMSIDPSDPNWLGRDRFIMSAGHSSLTQYT
QLYLAGLGLELSDLESLRTWGSLTPGHPEYGLTKFVETTTGPLGAGVANAVGMAMAARRERGLLDPDAAPGTSLFDHYIY
AIAGDGCMQEGIASEASSLAGTQELGNLIMFYDDNRITIEGDTAIAFSENVEARYEAYGWHVQHVDFTNGGTTYEENVEA
LMEAIDNAKTVTDKPSFIRLTTVIGWPIPKLAGLAQVHGAKIGAEGVSALKEKLGFEDKPFAIDLEMVQQVRAAFAERGK
GLREVWDEKFAAWHDANPDGAALLERMLAHKLPDDLDIPTFEPGKMSTRKASGAVLSALGPQLPELWGGSADLAGSNNTT
MKGADSFLPEDRCSEKDPGGPYGRTIHFGVREHAMGGILNGITLAGLTRCYGGTFFVFSDYMRPSVRLAALMKIPSIFVW
THDSIGVGEDGPTHQPVEHLASYRAIPGLDIVRPADANETAVAWRTIVEHTDRPAGLVLSRQDLPTIDRSKYASAEGVAR
GAYVVCEASAEPKVILIGTGSELSVALEAREKLEADGIATRVVSMPCQEWFDEQDEEYRESVLPSSVTARVSVEAGIAMG
WAKYVGCKGASVSLEHFGASASGALLFEKFGFTADHVAEVAHTVFME

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-111 45
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 8e-104 42