Gene Information

Name : clpB (HMPREF0675_5086)
Accession : YP_003582212.1
Strain : Propionibacterium acnes SK137
Genome accession: NC_014039
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2146428 - 2149001 bp
Length : 2574 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGGACACCAATCTCACCACGATGAGCCGTGACGCGGTCACCGCCGCTACTCGGCATGCGTTGGCCCACGGGAACCCATC
CGTGGAGCCCTCGCATCTTCTTCACGCACTGTTCACGATCCCAGACAACACTGTCAGTCCGTTGGTAGCTGGCTTGGGGA
TTGATCCTCAGCAGGTCGACGCCGTCGCTACCGCAGCGATGCGCTCCCTTCCGTCAAGTACCGGCGCCTCAGTAGCTCAG
CCGCAGCTGTCCGGGGCCTTCGCCCGAGTCATCGCCGACGCGCAGAACCGTGCCGAGGCCATGGGCGATTCCTTCGTCGC
TACCGAGCATCTTCTTATTTCGCTGACGGCGGTTCCCTCCGACGTCCAGAACGGCCTGGCAGGGCTCGGCCTCAAGCCCG
ACTCCCTCGCGGCGGCCTTCAATGAAGGTCGTGGAGACCGTCGTGTCACCTCCGAGGAGTCCGAGGGAGGCGAATCGGCT
CTCGCCAAGTACTCCGTCGATCTCACCGAGCGCGCCCGTGCCGGCAAGCTCGACCCCGTCATTGGTCGTGACCAGGAGAT
TCGCCGCGTCGTCCAGGTGTTGGCGCGACGCACTAAGAACAACCCGGTCCTTATCGGTGAACCGGGGGTCGGCAAGACTG
CCGTCGTCGAGGGGTTGGCTCAGCGCGTCGTCGCCGGGGACGTTCCCGACTCTCTCAAAGGGCGTCGCGTCGTCTCTTTG
GATCTGTCCTCCATGGTTGCCGGGGCTAAATACCGCGGCGAGTTTGAGGAGCGCCTCAAGGCCGTCCTCAACGAGATCAA
GGAGGCCGAGGGGCAGATCATTACCTTTATCGATGAGCTGCACACCGTCGTCGGCGCCGGGGCTTCCGGAGAGGGAGCAA
TGGACGCTGGCAATATGCTCAAGCCGATGCTGGCCCGTGGCGAGCTGCGAATGATCGGTGCCACTACCCTCGACGAGTAC
CGCGAGCATATTGAGAAGGACCCAGCTCTGGAGCGTCGTTTCCAGCAGGTCTTTGTCGGTGAACCGTCGGTTGAGGACAC
TATTGCCATCTTGCGCGGCTTGCGAGAGCGCTACGAGGCCCACCACAAGGTGCGTATTACTGACGGAGCCCTTGTCGCGG
CCGCCAGCTTGTCTCACCGGTGCATCACCGCCCGTCAGCTTCCTGACAAGGCCATTGACCTTATCGACGAGGCTGCGTCT
CGGCTGCGCATGGAGATTGACTCCTCTCCGGAGGAGATCGACACCCTGCGCCGTGAAGTCGACCGCATGAAGATGGAGAT
CTTCGCCGTCGAGAAGGAGGACGACCCGGCCAGCCAGCAGCGCCTAACGAGGTTGCGCGCTGACATGGCTGACAAGGAGG
AGACCCTGCGCGGCCTGGAGTCGCGCTGGGAGGCTGAGAAGGCTGGTCTCAACAAGGTCGGTGAGCTCAAGACAAGGATT
GACGAGTTGCGGACTGCGGCCGACAAGTACCAGCGCGAGGGCGACTTCGGGCGAGCGTCCGAGATCCTCTACGGTCAGAT
TCCCGGCCTTGAGAAGGAGATGGAGGCTGCTGCCAAGGCTGAGGAGGAGACCCCACGGATGGTGTCCGAGGAGGTCGGTA
CCTCCGACATTGCCGAGGTTGTTTCCTCGTGGACCGGCATCCCCGTGGGGCGGATGATGCAAGGCGAGCAGGAGAAGCTG
CTCCATATGGAGGAGCGGCTGCACGAACGTCTTATTGGTCAGGATCGAGCTGTCAAGACCGTCTCGGATGCGGTGCGTCG
CTCCCGGGCCGGAATCAGCGACCCGAACCGTCCGACTGGCTCGTTCCTCTTCCTGGGCCCCACGGGCGTCGGCAAGACCG
AGTTGGCCAAGTCCCTGGCGGAGTTCCTCTTCGACGACGAGACCGCTCTGGTGCGTATTGACATGAGTGAGTACATGGAG
AAGCACTCCGTCTCACGTCTGGTCGGTGCCCCTCCGGGTTACATCGGTTACGAAGAGGGCGGTCAGCTTACCGAAGCTGT
GCGGCGTCGCCCCTACTCGGTTATCTTGCTCGACGAGGTGGAAAAGGCTCATTCCGACGTCTTTAACATTTTGTTGCAGG
TGCTCGACGACGGTCGTCTGACTGACGGCCAAGGACGCACGGTGGATTTCCGCAACACCATTTTGGTCTTGACGAGCAAT
CTGGGTAGCCAATTCCTGTCAGACGCGAGCCTTGATGACCATGCTAAGCGTGAGGCCGTCATGGGGGCGGTGCGTCAGGC
GTTTCGACCCGAGTTCCTGAATCGACTCGACGATGTGGTCATGTTCGACCCGTTGTCGATGGCCGATCTGGGACGGATCG
TCGAGACGAACCTGGCTAAGCTCAATTCACGGCTGGCCGAGCGGCGCATCACCATTGCCGTGACCGACGCCGGTAAGGAC
TGGCTGGCCATGGCGGGTTTCGACCCGATCTACGGTGCCCGACCACTGCGTCGCCTGATGCAGACCACCATCGATGATCA
GCTGGCTCGCAAGGTGTTGTCTGGGCAAGTGCAGGAGGGCGATACGGCGACCTTTGACATCAACGAGGCCGGTGACGGTT
TGGTGATTCTCTGA

Protein sequence :
MDTNLTTMSRDAVTAATRHALAHGNPSVEPSHLLHALFTIPDNTVSPLVAGLGIDPQQVDAVATAAMRSLPSSTGASVAQ
PQLSGAFARVIADAQNRAEAMGDSFVATEHLLISLTAVPSDVQNGLAGLGLKPDSLAAAFNEGRGDRRVTSEESEGGESA
LAKYSVDLTERARAGKLDPVIGRDQEIRRVVQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRRVVSL
DLSSMVAGAKYRGEFEERLKAVLNEIKEAEGQIITFIDELHTVVGAGASGEGAMDAGNMLKPMLARGELRMIGATTLDEY
REHIEKDPALERRFQQVFVGEPSVEDTIAILRGLRERYEAHHKVRITDGALVAAASLSHRCITARQLPDKAIDLIDEAAS
RLRMEIDSSPEEIDTLRREVDRMKMEIFAVEKEDDPASQQRLTRLRADMADKEETLRGLESRWEAEKAGLNKVGELKTRI
DELRTAADKYQREGDFGRASEILYGQIPGLEKEMEAAAKAEEETPRMVSEEVGTSDIAEVVSSWTGIPVGRMMQGEQEKL
LHMEERLHERLIGQDRAVKTVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKSLAEFLFDDETALVRIDMSEYME
KHSVSRLVGAPPGYIGYEEGGQLTEAVRRRPYSVILLDEVEKAHSDVFNILLQVLDDGRLTDGQGRTVDFRNTILVLTSN
LGSQFLSDASLDDHAKREAVMGAVRQAFRPEFLNRLDDVVMFDPLSMADLGRIVETNLAKLNSRLAERRITIAVTDAGKD
WLAMAGFDPIYGARPLRRLMQTTIDDQLARKVLSGQVQEGDTATFDINEAGDGLVIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-107 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003582212.1 ATP-dependent chaperone protein ClpB VFG2084 Protein 3e-110 43