Gene Information

Name : clpC (PRU_0812)
Accession : YP_003574166.1
Strain : Prevotella ruminicola 23
Genome accession: NC_014033
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 945874 - 948408 bp
Length : 2535 bp
Strand : -
Note : identified by similarity to SP:P37571; match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGACGACACAATTTTCGCCAAAACTATCAGAAATACTGGCTTTCTCGCGTGAAGAGGCAGCTCGACTGGCTAGCCGATC
GGTGGGTCCCGAACACCTACTGCTTGGCATTCTGCGCAGTAACGAGGGTCCGGTTATCGACCTGTTTAACAGGCTGAACC
TGAATATGCAGGCGGTAAAGACTGAACTGGAAATGCGCGTAAGGGAGGACGAAATCGGTCAGCCTATACACACTACCGAC
CTGGTGCTGAACGAGAAGGCCAGCAACGTACTGCGACTGGCTGTACTGGAGGCACGCATACAGAGAGCCAATAAGATAGA
CGAGCAACACCTGCTGCTGGCCATACTGCACGACTTGGCTAACAACGGGGCAAAACAAGTTTTAGAAATGAACGATGTGA
CATACGACGACGCTGCAGCCATACTGTTTGCGCCGAAGAACACAAACGTAAGTAATAACGTGAGCAACGGCATAGGACTG
CCCGACGAGGAGGAAGAGGAGTTTGAGATGAATGGCGACAAGGGCATTCCGGTGAGCAAGATTAATAACACCGCCCAGAA
GAAGCCCGCCTCGAAGACACCTGTACTCGACAGCTTTGGTACCGACCTGACAAAGGCCGCTGCTGATGGTAAGCTGGATC
CCTGTGTGGGTCGCGAGCGCGAGATACAGCGTATTGTAGAGATTCTGGGTCGCCGCAAGAAGAACAACCCCATACTGATT
GGCGAGCCTGGTGTAGGTAAGAGCGCCATTGTAGAGGGACTGGCCCAGATGATTGAGGCCCACCACTGCAGTCCAATGCT
GTTTGGAAAGCGCATTTTTACGCTGGATATGACAGGCGTTGTGGCAGGCACCAAGTATCGCGGACAGTTTGAGGAGCGCC
TGAAAGCCCTGATGAAGGAGCTGGAGGCTAACCCCGACGTGATTGTATTCATCGACGAGATACACACCATCATCGGTGCA
GGTTCTACCCCTGGCAGTATGGATGCTGCCAACATTATGAAACCTGCCTTGGCACGCGGCACCATACAGTGCATTGGTGC
TACCACGCTGGATGAGTATCGCGAGAGCATTGAGAAGGATGGTGCCTTGGAGCGTCGATTCCAGAAGGTGCAGGTAGAGG
CTACCACCAACGAGGAGACGCTGCAGATTCTGCGTAACATCAAGGATCGCTACGAGCAGCACCACCACGTGACATATACC
GACGCGGCACTCGAGGCCTGTGTCAAATTGACAGACCGATACATTACCGACCGCTTTATGCCAGATAAGGCCATCGACGC
GCTGGACGAGACTGGTTCGAAGGTACACTTAGGCAACGCACAGATTCCACCCGAGATTATTGAGAAGGAGAAGGAGCTGG
CCGATGCCCGCGAAAAGAAGCAGAAGGCGGTAAAGAACCAGAACTACGAGCTGGCAGCCGGTTATCGCGACCGCGAGACA
ACCCTTACCAAGGAGTTGAAGGAGCTGAACGACCGCTGGAGCAACGGCGAGGGCGAAGAGCGACTGGTGGTAGATGCCGA
CCAGGTGGCCGAGGTGGTTTCGATGATGACGGGTGTGCCCGTACAGCGCATGGCCGAACAGGAGGGTGTACGCCTGAAGG
GTATGGCCGTAGAGCTGAAGAACGCCGTGATAGCCCAGGATGCCGCTATCGACAAGATGGTAAAGGCCATCCAGCGCAAC
CGTGTAGGACTGAAGGAGCCCAACCACCCTATCGGCGTGTTTATGTTCTTAGGTCCTACAGGTGTGGGAAAAACCTACCT
GGCCAAGAAGCTGGCAGAGTTTATGTTTGGCAGCAGCGAGGCGCTGATTCGTATCGACATGAGTGAATATACCGAGAGCT
TTAACACCTCGCGACTGATTGGTGCACCTCCGGGATACGTAGGTTACGGCGAGGGCGGACAGCTGACAGAGCGCGTGCGC
CGTCACCCCTACTCGATTGTTCTGTTGGACGAGATTGAGAAAGCTCACAGCAACGTGTTCAACCTGTTGCTGCAGGTGCT
TGACGAGGGACGCATGACAGACGGTAACGGACGACTGGTGGATTTCCGCAACACGGTGATTATCATGACATCGAATGCAG
GTACTCGCCAGCTGAAGGACTTTGGCCGTGGCGTAGGTTTCGGTGCATCGGCACAGACGGGACTGATGAAGAGCGACAAG
GACAAGCAGTATGCACGCGACATTGTACAGAAGGCACTGTCGAAGCAGTTCTCGCCTGAGTTCCTGAACCGACTGGATGA
GATTATCACCTTCGACCAGCTGGATCTGGATGCCATCAAGCGCATTATCGATGTAGAGCTGAAGAGCCTGTACAACCGTA
TTGAGCAGATAGGCTATCACATCGACCTGAGCGACGAGGCCAAGGAGTTTGTGGCCACCAAAGGTTACGATGTGCAGTTT
GGTGCCCGTCCGCTAAAGCGCGCTATACAGAACTATCTGGAGGATGGCATTAGCGACCTGATAGTGAATGGCGACCTTGA
ACCGGGAGCCACCATCCATATCACACTTAAAGAAAATGAGTTAGCGTTTAGCTAA

Protein sequence :
MTTQFSPKLSEILAFSREEAARLASRSVGPEHLLLGILRSNEGPVIDLFNRLNLNMQAVKTELEMRVREDEIGQPIHTTD
LVLNEKASNVLRLAVLEARIQRANKIDEQHLLLAILHDLANNGAKQVLEMNDVTYDDAAAILFAPKNTNVSNNVSNGIGL
PDEEEEEFEMNGDKGIPVSKINNTAQKKPASKTPVLDSFGTDLTKAAADGKLDPCVGREREIQRIVEILGRRKKNNPILI
GEPGVGKSAIVEGLAQMIEAHHCSPMLFGKRIFTLDMTGVVAGTKYRGQFEERLKALMKELEANPDVIVFIDEIHTIIGA
GSTPGSMDAANIMKPALARGTIQCIGATTLDEYRESIEKDGALERRFQKVQVEATTNEETLQILRNIKDRYEQHHHVTYT
DAALEACVKLTDRYITDRFMPDKAIDALDETGSKVHLGNAQIPPEIIEKEKELADAREKKQKAVKNQNYELAAGYRDRET
TLTKELKELNDRWSNGEGEERLVVDADQVAEVVSMMTGVPVQRMAEQEGVRLKGMAVELKNAVIAQDAAIDKMVKAIQRN
RVGLKEPNHPIGVFMFLGPTGVGKTYLAKKLAEFMFGSSEALIRIDMSEYTESFNTSRLIGAPPGYVGYGEGGQLTERVR
RHPYSIVLLDEIEKAHSNVFNLLLQVLDEGRMTDGNGRLVDFRNTVIIMTSNAGTRQLKDFGRGVGFGASAQTGLMKSDK
DKQYARDIVQKALSKQFSPEFLNRLDEIITFDQLDLDAIKRIIDVELKSLYNRIEQIGYHIDLSDEAKEFVATKGYDVQF
GARPLKRAIQNYLEDGISDLIVNGDLEPGATIHITLKENELAFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-163 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_003574166.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 8e-150 51
clpC YP_003574166.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 0.0 47