Gene Information

Name : pyk (PRU_0684)
Accession : YP_003574044.1
Strain : Prevotella ruminicola 23
Genome accession: NC_014033
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 803800 - 805245 bp
Length : 1446 bp
Strand : +
Note : identified by similarity to SP:P14178; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAAGCAGACAAAAATTGTAGCTAGCATTAGTGACAGAAGATGTGATCAGGATTTCATCCGCAGTCTCTTCGAGGCAGG
CATGAATGTAGTGAGAATGAACACGGCGCATGCCGATGAACAGGGTATTAAAAACATAATTAATAATGTGCGTAGCGTGA
GCCACCACATTGGTATCCTTATCGATACCAAGGGTCCTGAGGTGCGTACCACCGGATGCCCAGAGCCCATCGCCTATAAA
ACAGGTGATGTGGTGAAGATTTTCGGTCGCCCCGAAATGGATACCACGCACGACATCATTAACCTGTCGTATGCCGACTT
TGCTGCCGACGTACACGAGGGTTGTCATATCCTGTTCGACGACGGTGCACTCGACATGAAGGTGATCGGTATCAACGGTC
CAGCTGTAATCGCTCAGGTGCAGAACGACGGTGTGCTGGGTTCGCACAAGAGCGTAAACGTGCCCGGTGTTCACATCGCA
CTGCCTACGCTGACCGAGAAGGACCGCAAGAACATTAAACTGGCCATCGACCAGGACATCGACTTTATTGCTCACAGCTT
TGTGCGCTCGGCTGCCGACGTGCGTGCCGTGCAGGCTATCCTGGATGCCTACAACAGCGACATCAAGATTATCTCGAAAA
TCGAGAACCAGGAGGGTGTGGACAATATCGACGAGATTATCGAGGCTTCGTACGGTATCATGATTGCACGTGGCGACTTG
GGTATCGAGGTGCCCATCGAGCGTATTCCTGGTATCCAGCGACAGATTATCCGCAAGTGCGTACGCGCTAAGAAGCCTGT
AATCGTTGCTACACAGATGCTGCACACCATGATTAATAACCCACGCCCCACACGCGCCGAGGTTACTGATATTGCTAATG
CTATCTACTATCGCACCGATGCACTGATGCTGTCGGGCGAGACTGCCAGCGGAAAATATCCTGTAGAGGCCGTTCGCACC
ATGGCCGCTATCGCCGAACAGGCTGAGAAGGACAAGATGCGCGAGAACGACATCGAGGTGCCCCTGTCACCAACATGCGA
TATCCGCGAGTTTATGGCTCACTCGGCTATCGAGGCCACCGAAAAGCTGGGTGTGAAGGGTATCATCACCGACGCCAGCT
CGGGCGACACCGCTCGCAACCTGGCTGCCTTCCGTGGTCCTAACCCCGTGCTGGCTATCTGCTACAACGATAAACTGCAG
CGTCTGCTGAACCTTTCATATGGTGTAATCCCTGTATTTCAGAAGGAGCATATCGACAACGAGGTGCTGTTCCATGCGGC
TGTACGCATGCTGCGCCAGAAGGGTTACGTGCAGGATGCTGATAAGATTGCCTACCTGAGTGGAAACGTAGGCGAGGGCG
GTGGCACCAAGTTCCTGGAGATTAACACCGTGAAGGAGGTGATGACCAACCAGTATAAGTTCCACCTGCCACACTCAAAT
AAATAG

Protein sequence :
MKQTKIVASISDRRCDQDFIRSLFEAGMNVVRMNTAHADEQGIKNIINNVRSVSHHIGILIDTKGPEVRTTGCPEPIAYK
TGDVVKIFGRPEMDTTHDIINLSYADFAADVHEGCHILFDDGALDMKVIGINGPAVIAQVQNDGVLGSHKSVNVPGVHIA
LPTLTEKDRKNIKLAIDQDIDFIAHSFVRSAADVRAVQAILDAYNSDIKIISKIENQEGVDNIDEIIEASYGIMIARGDL
GIEVPIERIPGIQRQIIRKCVRAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETASGKYPVEAVRT
MAAIAEQAEKDKMRENDIEVPLSPTCDIREFMAHSAIEATEKLGVKGIITDASSGDTARNLAAFRGPNPVLAICYNDKLQ
RLLNLSYGVIPVFQKEHIDNEVLFHAAVRMLRQKGYVQDADKIAYLSGNVGEGGGTKFLEINTVKEVMTNQYKFHLPHSN
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-72 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-71 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-72 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003574044.1 pyruvate kinase VFG0479 Protein 8e-73 41