Gene Information

Name : guaA (PRU_1678)
Accession : YP_003574973.1
Strain : Prevotella ruminicola 23
Genome accession: NC_014033
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2028490 - 2030094 bp
Length : 1605 bp
Strand : -
Note : identified by similarity to SP:P04079; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM PF06508; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGACACAGAAGATTATTATTCTCGATTTCGGTTCGCAAACCACGCAGCTTATCGGCCGCCGTGTGCGCGAGCTGGACAC
CTTCTGCGAGATTATGCCCTACAACAAATTTCCGAAGGACGATCCCTCGGTGATTGGTGTAATTCTGAGTGGTTCGCCCT
ACTCGGTACACGATCCTGAGGCTTTCAAGGTCGACCTGTTGCAGTTTGTAGGTCGTGTGCCAGTGCTGGGTATCTGCTAT
GGTGCTCAGTTCATCAGTCACACCCTGGGTGGTAAGGTCGAAAAGGCCGACTCTCGCGAGTATGGACGTGCCAACCTTGA
GACTGTCGACACCACGAATCCCCTGTTCAAAGGTTTCGAGCAGCACTCACAGGTATGGATGAGCCATGGCGACACCATCA
CCTCAATCCCCGAGGGTTTCGAGGTTATTGGTTCTACTAAGGACGTTAAGAACGCTGCATTCTGGCGCGATGGCGTATGG
GCTGTACAGTTCCACCCCGAGGTGTTCCACACCCTGCAGGGCACACAGCTCCTGAAGAACTTCGTAGTTGATATCTGTGG
CAGTAAGCAGGAGTGGAGTGCCGCTTCGTTCGTCGATTCTACAGTAGCTGAGCTCAAGGCTCAGCTGGGCGACGACCGTG
TGATTCTCGGCCTCTCAGGTGGTGTCGATTCATCTGTTGCTGCTGTACTGCTCAACAAGGCTATCGGCAATCGCCTTACC
TGTATCTTTGTAGATCATGGTATGCTGCGTAAGAACGAGTTCAACCAGGTAATGGACGACTACAAGGTGCTGGGCCTGAA
CGTGATTGGTGTTGATGCCAGCGCTAAGTTCTTTGCCGATCTGGCTGGTGTTACCGATCCTGAGCAGAAGCGTAAGATTA
TCGGTCGCGACTTTGTCGAGGTGTTCAATGCCGAGGCTAAGAAGATTACCGATGCCAAGTGGCTGGCTCAGGGTACTATC
TACCCCGACCGTATCGAGAGCTTGAATATTACAGGTAAGGTGATTAAGAGCCACCACAACGTAGGCGGTCTGCCTAAGGA
AATGCACTTGCAGCTTTGCGAGCCCCTGCAGTGGTTGTTCAAGGACGAGGTTCGTCGTGTAGGTCGCCAGTTGGGCATGC
CCGAACACTTGATTACCCGTCACCCCTTCCCTGGTCCTGGCTTGGCTGTTCGTATCCTGGGCGATATCACTCCTGAGAAG
GTACGTATCCTGCAGGATGCCGACGATATCTATATCCGCGGTCTGCGCGATTACAAGGTAAAGCTGAGTGGCGAAGAGGC
CCGCAAGGTGCTGGCTGCCGGTATCCCTGCCGATATGAAGGATGGCGAGATCGAGGTTTCGCTCTACGATCAGATCTGGC
AGGCAGGTGCCATCCTGCTTTCTACTGTTCGCAGTGTAGGTGTGATGGGCGATGAGCGTACCTACGAGCATCCCGTAGCC
CTGCGTGCTGTAACCAGTACCGATGCAATGACAGCCGACTGGGCACATCTGCCTTACGACTTCATGGCTAAGGTAAGTAA
CGAGATTATTAATAAGGTACGTGGCGTAAACCGCGTTTGCTACGATATCTCGTCGAAACCACCCGCAACCATCGAGTGGG
AGTAA

Protein sequence :
MTQKIIILDFGSQTTQLIGRRVRELDTFCEIMPYNKFPKDDPSVIGVILSGSPYSVHDPEAFKVDLLQFVGRVPVLGICY
GAQFISHTLGGKVEKADSREYGRANLETVDTTNPLFKGFEQHSQVWMSHGDTITSIPEGFEVIGSTKDVKNAAFWRDGVW
AVQFHPEVFHTLQGTQLLKNFVVDICGSKQEWSAASFVDSTVAELKAQLGDDRVILGLSGGVDSSVAAVLLNKAIGNRLT
CIFVDHGMLRKNEFNQVMDDYKVLGLNVIGVDASAKFFADLAGVTDPEQKRKIIGRDFVEVFNAEAKKITDAKWLAQGTI
YPDRIESLNITGKVIKSHHNVGGLPKEMHLQLCEPLQWLFKDEVRRVGRQLGMPEHLITRHPFPGPGLAVRILGDITPEK
VRILQDADDIYIRGLRDYKVKLSGEEARKVLAAGIPADMKDGEIEVSLYDQIWQAGAILLSTVRSVGVMGDERTYEHPVA
LRAVTSTDAMTADWAHLPYDFMAKVSNEIINKVRGVNRVCYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-114 48
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-114 48
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-114 47
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-107 45