Gene Information

Name : clpB (PRU_0121)
Accession : YP_003573523.1
Strain : Prevotella ruminicola 23
Genome accession: NC_014033
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 149429 - 151939 bp
Length : 2511 bp
Strand : -
Note : identified by similarity to SP:P53533; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGACATTCGACAAGTTTACAATTAAAGCACAAGAGGCCATTCAGCAGGCGGTGAACGCGGCCCAGATGAATGGTCAGCA
GGTGATAGAACCTGTACACATACTGAAAGGTGTGATAGAGAAGGCGAAGGATGTAACCACCTTCATCTTCCAGAAGTTGG
GTGTAAATGCCCAGCAGATAGAGTTACTGGTAGATCAGGAGATACAGCATCTGCCCAAAGTACAGGGTGCTGGTCAGCCT
TATCTCTCCAGTGATAGTAATAATGTACTCGTGCGCGCGCAAGAGGTAGCCCAGAAAGGTGGCGACGAGTTTGTATCGGT
AGAACCTATCCTACTCGCCCTGCTGAAAGTTAATTCTACTGCCTCGCGCATCATGAAGGATGCCGGCTGTACCGAGAAGG
ATATGCAGGCGGCTATCCAGGAGCTGCGCCAGGGACAGAAGGTGCAATCGCAGAGTGCCGATGATAACTACCAGAGCTTG
GAGAAATATGCCAAGAACCTGGTGGATTTGGCCCGCCAAGGCAAGCTGGACCCAGTGATTGGTCGCGACGATGAGATTCG
TCGTGTACTGCAGATTCTGAGTCGCCGCACCAAGAACAACCCTATATTAATAGGTGAACCTGGTACAGGTAAAACAGCCA
TCGTTGAGGGACTGGCTGGTCGTATTGTGCGTGGCGATGTGCCCGAGAACCTGAAGGACAAGCAACTCTACTCGCTGGAT
ATGGGTGCACTGGTAGCAGGTGCCAAGTACAAAGGTGAGTTTGAGGAGCGCCTGAAGAGTGTGATCAACGAGGTGACCAA
GGCCGAGGGCCGCATCATCCTGTTTATCGACGAGATCCACACCTTGGTAGGTGCAGGTGGTGGCGAGGGCGCCATGGATG
CAGCCAACATTCTGAAACCTGCCCTGGCACGTGGTGAACTGCGTGCCATAGGTGCCACCACGCTGAACGAGTATCAGAAA
TACTTTGAGAAGGATAAGGCCCTGGAGCGCCGATTCCAGACCGTGATGGTAGATGAGCCCGATGAACTGAGTGCTATCAG
CATTCTGCGAGGCTTGAAGGAACGTTACGAGAACCACCACAAGGTACGTATCCAGGACGATGCCTGTATCGCTGCCGTGC
AACTCTCAGAGCGCTATATCTCTGAAAGATTCCTCCCCGACAAGGCCATCGACCTGATGGACGAGGCCGCAGCAAAACTG
CGCATGGAGCGCGACTCGGTACCTGAGGAGTTGGATGAGATTACCCGCCGACTGGCTCAGCTCGAAATCGAGCGTGAGGC
TATCAAAAGAGAGGGCGACACCCAGAAGATAGCACAGTTGGATAAGGACATCGCCGAACTGAAGGAACAGGAAACCCAGT
TCCGTGCCAAGTGGGAAGGCGAGCGCCAACTCATCAACAAAATCCAACAGGACAAGCAGGATATTGAGAACCTGAAGCTG
GAGGCAGAACGTGCCGAGCGCGAGGGCGACTACGGCAAGGTAGCCGAGATACGCTACTCGAAACTGAAAGCACTTGAGGA
CGACATTGCACATATCCAGAGTCAGCTGGCCAATGCCCAAGGCGATAACTCTCTGGTTCGCGAAGAGGTTACCGCCGATG
ACATCGCCGAGGTAGTAAGCCGCTGGACAGGTATCCCCGTAACCAAGATGATGCAGAGCGAGCGCGAAAAGCTGTTGCAC
TTAGAGAATGAGTTGCACAAGCGTGTGATTGGTCAGGACGAAGCCATCATTGCCGTATCTGATGCTGTGCGCCGTAGTCG
TGCTGGCTTGCAGGATCCCAAGCGTCCTATCGCCAGCTTCATCTTCCTTGGTACCACAGGTGTAGGTAAAACAGAGCTTG
CCAAAACCCTGGCCGACTATCTGTTTAACGACGAGACCATGATGACGCGTATCGACATGAGCGAGTATCAGGAGAAATAC
AGCGTGAGCCGACTGATTGGTGCGCCTCCAGGATACGTAGGCTACGACGAGGGTGGACAACTGACCGAGGCCGTGCGCCG
CAAGCCTTACTCGGTAGTGCTGTTCGATGAGATTGAGAAGGCCCATCCGGATGTGTTCAACATTCTGTTGCAGGTGCTGG
ACGATGGACGTTTGACGGACAACAAGGGACGTACCGCCAACTTCAAGAACACCATCATTATCATGACCTCGAACGCCACC
CGTGAGCAACTCAGAGCCACTATGCGCCCAGAGTTCCTGAACCGTATTGATGAGATTATCACCTTTACACCTCTTACCAA
GGAACAGATTGCCGACGTAGTGAAGTTGCAGATGAAGAAGGTTACCGATATGCTGGCACCTCAGGGCATCACCTTAGAGT
GTACACCACAGGCCATCGACTATCTGGCCGAGCAGGGTTACGATCCCGACTATGGTGCTCGTCCTGTAAAGCGTGCCATC
CAGCAGTTCGTGCTCAACGACCTGTCGAAGAAGATCCTGTCGGATGAGGTGGATCGCACCAAACCTATCATCATCGATGA
ATACGGCGAAGGACTGATTTTTAGAAACTAA

Protein sequence :
MTFDKFTIKAQEAIQQAVNAAQMNGQQVIEPVHILKGVIEKAKDVTTFIFQKLGVNAQQIELLVDQEIQHLPKVQGAGQP
YLSSDSNNVLVRAQEVAQKGGDEFVSVEPILLALLKVNSTASRIMKDAGCTEKDMQAAIQELRQGQKVQSQSADDNYQSL
EKYAKNLVDLARQGKLDPVIGRDDEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAGRIVRGDVPENLKDKQLYSLD
MGALVAGAKYKGEFEERLKSVINEVTKAEGRIILFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATTLNEYQK
YFEKDKALERRFQTVMVDEPDELSAISILRGLKERYENHHKVRIQDDACIAAVQLSERYISERFLPDKAIDLMDEAAAKL
RMERDSVPEELDEITRRLAQLEIEREAIKREGDTQKIAQLDKDIAELKEQETQFRAKWEGERQLINKIQQDKQDIENLKL
EAERAEREGDYGKVAEIRYSKLKALEDDIAHIQSQLANAQGDNSLVREEVTADDIAEVVSRWTGIPVTKMMQSEREKLLH
LENELHKRVIGQDEAIIAVSDAVRRSRAGLQDPKRPIASFIFLGTTGVGKTELAKTLADYLFNDETMMTRIDMSEYQEKY
SVSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTANFKNTIIIMTSNAT
REQLRATMRPEFLNRIDEIITFTPLTKEQIADVVKLQMKKVTDMLAPQGITLECTPQAIDYLAEQGYDPDYGARPVKRAI
QQFVLNDLSKKILSDEVDRTKPIIIDEYGEGLIFRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-97 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-97 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_003573523.1 ATP-dependent chaperone protein ClpB VFG2076 Protein 4e-118 43
clpB YP_003573523.1 ATP-dependent chaperone protein ClpB VFG2084 Protein 4e-100 43