Gene Information

Name : acrB (SRM_00092)
Accession : YP_003569965.1
Strain : Salinibacter ruber M8
Genome accession: NC_014032
Putative virulence/resistance : Resistance
Product : cation/multidrug efflux pump AcrB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 101815 - 104865 bp
Length : 3051 bp
Strand : +
Note : -

DNA sequence :
ATGGACATCGCCAAGGCCGCCATCGAGAACCGGACGCTGACGTACGTCACCACGTTGCTCGTGGTGGTGGGGGGCGTCAT
TGCGTTCCTGAACCTGGGGCGCCTGGAGGACCCGGAGTTTACCATTAAGCGCGCCCTGGTGGTGACCCAGTACCCGGGGG
CGACCGCCCACGAGGTGGAGGCGGAGGTGTCCGACCCCATCGAGGAGGCCGTTCAGGCAATGGGAAAGGTGAAGGAGATC
AAGTCCCGCTCCAGCCGGGGGCGCTCGACTTTGGAGGTCGAGATGAAGAGCGACGTCATCGGGGATGCGGTGACGCAGGC
CTTCGACGACCTGCGCGACAAGGTCAACGACGCTCAGGGACGCCTGCCGCCCGGGGCGGGCCCGTCCGTCGTGGAGGACG
ACTTTGGGGACGTGTACGGCATCTTTATGGCCATTACCGGGGAGGGCTACAGCAAGCAGGAGCTGAAGGACCACGCGGAG
GCCCTGAAGCGGGAGCTGGTGCAGGTGCAGGGCGTCGCGAAAGTTCGCCTTTTTGCGGACCGACAGGAGACCATCTACGT
CGAGCCGAACCGCGACCGGTTGTCGAACCTGGGGATCAGTGTCGACCGGATCGCGGGAAGGCTGCGCACACAGAACACTG
TCGTTGATGCCGGGCGCGTGCGGGTGGGGGACAGCCACATTTCGGTCCGGCCGTCGGGGGCAACGGCGTCGCTGGACGAC
CTGCGGTCGATTCTGATCGCGAGTCAGGGGGGACGCCAAATCTTCCTGGAGGACATCGCCACGGTGCGGCGCGGCTACGC
CGCCCCGCCCCGGGCCCTCATGCGGTACGACGGCGAGCCGGCAATCGGCCTCGGCGTATCGACCGTCGACGGGGGCAACG
TCGTTACGATGGGACGGGCCGTGAAGGCCCGCCTCGATGAATTGAAGGCCGATCGCCCCGTGGGCATCGAGTACAACTAC
ATCAACTTCCAGGCCGAGGACGTGAGCGAGGCGGTGAGTGGCTTTGTCTGGAACCTGGTCACCGCCATCGCGATCGTGAT
CGTCGTGCTGCTGCTGGCGATGGGGTGGCGCAGCGGGCTCCTCATGGGGTTTGTGCTGGCGGTGACCGTGCTCGGCACGT
TTATCCTGATGTACGCGACGGACGTGGTGCTGCAGCGGATCTCGCTGGGCGCGCTCATCATCGCGCTCGGGATGCTCGTC
GACAACGCCGTGGTGATCGTGGACGGCATCCTGACGCGCCTCAAGGAGGGGCGGGAGCGGGTGGAGGCCGCGTCGGAGAT
TGTGGAGCAGACGAAGTGGCCGCTCTTCGGGGCCACGGCCGTGGCCATCCTGGGCTTCGCCGCCATCGGGACCTCCTCCG
ACAGCAGCGGGGAGTTTTTGGGGTCGTTGTTCCTCGTGATCCTCTACTCGCTGTCTCTGAGCTGGGTGCTCTCCGTTACG
CTCGCGCCGCTCCTGGGGGTTGACTTTCTGAAGAAGCCCGACCCGGACGAGGCGGTGGAGAGCGCCCACGACGGGCCGGT
CTACACTGTGTACCGGCGCCTGCTTCAGGGCGCGATCAACTACCGGTGGGTGACGGTGGCGGTCATCACGGTGCTCATGG
GGCTGTCGATCTGGGGGAGCGGGTTCGTCAAGCAGAGCTTCTTTCCCGACTCCACGCGGCCGCAGTTTCTCGTGGACGTG
TGGATGCCCCAGGGCACGCACATTCGGGACACTGAGGATGCCGTCAAGGAGGCGGAGCAGTATGTGCAGGGCCTCGACGC
CGTCACCCACGTCAGTTCGGTGGTGGGGCAGGGGGCGCTCCGGTTCGTGCTGCCGTACAGCCCGGAGCGGCCCAACTCGT
CCTACGCCCAGCTGATCGTGGACGTCGACGACTGGCGGACGATTTCCAGTCTCAAAGACTCGGTGGACGCCCGCCTCTCC
GCGATGCTGCCGCGGGCCAACGTGTACGCGTTTCCGTTTGTCTTCGGGCCCGGGGGCGGCACCGGGCGCATTCAGGCGCG
CATCAGCGGCCCCAACCCCGACTCGCTGCGGGCCATCGCCCAGCGCGTGGAGGGCATCTTTCGGGCGCACGACAACACCA
AGGCCGTCCGCAACGACTGGCGCAACCGGGTGGAGGTCACCCGCCCCCAGGTCGCCGAGGACGCGGCGAGTGCCCTTGGG
GTGACGCGCCCCGACGTGGCCCGCGCCGTTCAGCGGACCTTTGAGGGCACCCGCATGGGGGTGTACCGAAGAGGGGAGGA
CCTGCTGCCCATCATGATGCGGGCCCCGTCCGAGGAGCGGGCCCGCGCCAGCAACATGAAAAACGCGCAGGTGTGGAGTC
CCGTGGCGGGCGCGTACGTCCCGATCCGGCAGGTCGTCTCCGGGTTCGAGACCGGCTTCGAGGACGGCATTGTGTGGCGG
TACAAGCGCGCCCCGACGGTGAGCGTGTACGCCGACCCCATCTCGGGGACGGCGACCTCGGTCTTCCAGCAGGTGCGCCC
GACGGTGGAGAAGCTCTCGCTTCCGCGAGGGTACGACATCGAATGGGGCGGCCAGTACGAGAACTCGAACGAGGCCAATG
CCTCGCTCTTCTCGGCGGTCCCGATTTTCTTCGTGCTGATGGTGCTGATCACGGTGGCACTCTTCAACGCGCTCCGCCAG
CCGCTCATCATCTGGCTGACCGTGCCCCTGGCCCTGATCGGCGTGGTGGCGGGCCTGCTCGCCACGGGGGCGGCCTTCGG
GTTTACGGCCCTGCTGGGCTTCCTGAGCCTGTCGGGCCTGCTCATCAAGAATGCCGTCGTCGTGATCGACGAGATCGAGA
TCTGGAAGCAGGACGAATCGCTCTACCAGGCCATCGTGGGCGCGAGCGTCGTCCGGCTGCGCCCGGTCATGATGGCGTCG
ATTACGACGGCCCTGGGCATGATTCCGCTCTTTACCGACGCGTTCTTCGTGGCCATGGCGGTGACCATCACGTCCGGGCT
GCTCTTCGCCACGGTGCTCACAATGATCGTGGTACCGGTCCTCTACGCCATCCTCTTTGGCGTCGAGCGCCTCCCGTATT
CGGAACGCTAG

Protein sequence :
MDIAKAAIENRTLTYVTTLLVVVGGVIAFLNLGRLEDPEFTIKRALVVTQYPGATAHEVEAEVSDPIEEAVQAMGKVKEI
KSRSSRGRSTLEVEMKSDVIGDAVTQAFDDLRDKVNDAQGRLPPGAGPSVVEDDFGDVYGIFMAITGEGYSKQELKDHAE
ALKRELVQVQGVAKVRLFADRQETIYVEPNRDRLSNLGISVDRIAGRLRTQNTVVDAGRVRVGDSHISVRPSGATASLDD
LRSILIASQGGRQIFLEDIATVRRGYAAPPRALMRYDGEPAIGLGVSTVDGGNVVTMGRAVKARLDELKADRPVGIEYNY
INFQAEDVSEAVSGFVWNLVTAIAIVIVVLLLAMGWRSGLLMGFVLAVTVLGTFILMYATDVVLQRISLGALIIALGMLV
DNAVVIVDGILTRLKEGRERVEAASEIVEQTKWPLFGATAVAILGFAAIGTSSDSSGEFLGSLFLVILYSLSLSWVLSVT
LAPLLGVDFLKKPDPDEAVESAHDGPVYTVYRRLLQGAINYRWVTVAVITVLMGLSIWGSGFVKQSFFPDSTRPQFLVDV
WMPQGTHIRDTEDAVKEAEQYVQGLDAVTHVSSVVGQGALRFVLPYSPERPNSSYAQLIVDVDDWRTISSLKDSVDARLS
AMLPRANVYAFPFVFGPGGGTGRIQARISGPNPDSLRAIAQRVEGIFRAHDNTKAVRNDWRNRVEVTRPQVAEDAASALG
VTRPDVARAVQRTFEGTRMGVYRRGEDLLPIMMRAPSEERARASNMKNAQVWSPVAGAYVPIRQVVSGFETGFEDGIVWR
YKRAPTVSVYADPISGTATSVFQQVRPTVEKLSLPRGYDIEWGGQYENSNEANASLFSAVPIFFVLMVLITVALFNALRQ
PLIIWLTVPLALIGVVAGLLATGAAFGFTALLGFLSLSGLLIKNAVVVIDEIEIWKQDESLYQAIVGASVVRLRPVMMAS
ITTALGMIPLFTDAFFVAMAVTITSGLLFATVLTMIVVPVLYAILFGVERLPYSER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
acrB YP_003569965.1 cation/multidrug efflux pump AcrB BAC0428 Protein 5e-178 47
acrB YP_003569965.1 cation/multidrug efflux pump AcrB BAC0519 Protein 0.0 47
acrB YP_003569965.1 cation/multidrug efflux pump AcrB BAC0425 Protein 0.0 46
acrB YP_003569965.1 cation/multidrug efflux pump AcrB BAC0526 Protein 4e-180 44