Gene Information

Name : zntA (SRM_00112)
Accession : YP_003569985.1
Strain : Salinibacter ruber M8
Genome accession: NC_014032
Putative virulence/resistance : Resistance
Product : Cadmium-exporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 133178 - 135655 bp
Length : 2478 bp
Strand : +
Note : -

DNA sequence :
GTGCACAGTCCGTCCTCATCCGCCGTGGCCGAACAGGTTCAACTCGATCTCCCCGTCGCACTCCCACACGTCCCCGACGC
GATGGACGCGTGCGTTGATCGCCTCACGGACCGTCTCCGTGGGCAGCCGGGCGTGAGCAGGGCCCACGTGGTCCCCGCCA
CGAACGGCGCCCCGGACCGCCTCTGCGTGCACTACGACCCCGATACGATTGCGCGCTCTCGCATCCGGCGGCGCGTGCGG
AGTGTCGGCGCGGACCTGACCGACCGGTACGGGCACCTCGTCTGGGCCGTTGAGGGAATCTCACGTCCCCGGCGCGCCCG
GACCATCGCCAAGCGGCTGCGCCAAATCAATGGCGTGGTGGAGGCGGAGGCGCGTGCCGCCGAGCAGGTCCGCGTAGAGT
ACGACCGGTCGTCGACGAGTGCGGAGGAGATCCGCGACGTGCTCCGGTCGATGAACGTGCGGCCGCAGGGCGATCGGCTG
GCGGCGCAGGGGCTGGCGGCGGAGGCCGGCCGTGGAGACCGCGAGGAAGAACACGACCACGACCATGGCGGGATCTTCGG
CGAGAAGACGGAACTGATCGTTGCCGTCGCGGCCGGCGTGTGCGTGGCCCTGGGCGTTGGGCTTTCCGTCGTGGGCGGCA
CGCCCGGATGGGTCCCCTGGGGACTGTACGTCGGAGCCTACGCCCTTGGCGGGTATCACACCGTGCGGGAGGCGGTCGAG
ACGCTCCGGGCCGGCGAGTTTGAAGTAGATTTCCTCATGCTGGTGGCCGCGGGGGGAGCGGCGGTGCTCGGGAAATGGCT
GGAGGGGGCGTTTCTGCTGTTTCTCTTCTCCCTCGGCCACGCGCTGGAGCACTACGCGATGCGCCGCGCCCGCCGGGCCA
TCGAGTCGCTCGCCGACCTGGCCCCAGACACCGCGCTCGTCCGCCGCGACGGAGAAGAACGAGAGGTTTCCGTCGATCAG
CTGCGGGTGGGAGACACAGTCATCGTGAAGCCGAACGAGCGCATTCCGGCGGACGGATTCGTTACCCAGGGCGAGAGCGC
CGTCAACCAGGCCCCGGTGACTGGCGAGAGCGTGCCGGTGGACAAGACACCCGTCGAAACCCCGGCGGCCGCGCGGGACC
CGACGACCCTAGACCCGGCCCACCGCGTTTACGCCGGCACGATCAACGGGAGCGGCGTGCTGGAGGTACGCGTCACGAAG
CGGGCGGGCGAGTCGACCCTTTCACGGGTCGTACAGATGGTCACGGAGGCGGAAGCTGAGAAGTCCCCGACCGAACGCTT
CACTGACCGGTTTGAGCGGGTCTTCGTGCCGGCCGTCCTCGGGCTAGTGGGGCTTCTTCTCTTTGCCTGGGTGCCCCTCG
GCGAGCCCGTTGCCGACAGCTTCTACCGCGCCATGGCTGTGCTCGTGGCCGCCAGTCCGTGCGCCCTCGCCATCGCCACG
CCGAGTGCCGTGCTGAGCGCCCTGGCCCGGGCCGGGCAGGGGGGCGTGCTCGTGAAGGGGGGCGGCCCGCTCGAACACCT
CGGCCGACTCGGCGCCGTCGCGTTCGACAAGACGGGCACCCTCACGGAGGGGGCGCCCCGCGTCACGGACGTGCGTCCCC
ACAACGGAACGGCCGAAGAAGACCTTCTCCGGGCCGCCGTCGCCGCCGAACGGCTCAGCGACCACCCGCTGGCGGAGGCG
GTGGTCCAGTACGGGGACGAACACCTCGAAGGCCGCCCGCCCGAAGACGCGGCGGAAATGAGGGACATCACGGGGCGGGG
CATTCGGGCCTCTGTGGGAGGGCGTCCCGTGCACGTTGGGAACGCGGCTCTTTTCGACGAGGTCGGCGGCCCACCGCTCC
CGGACCCGCTCCGCGACGAGGTGGAGGCGTTGGAGGCCGATGGGCGAACGACGATGATTGTCCGTCGCGGGGACACCTAC
CTCGGCGTGGTGGGCCTCGCCGATGCGCCCCGTCCGGAGGCCGCGGGCGTGGTGGAGCGGCTGCGCCGCGCGGGCATCCG
GCGGATGGTCATGCTTTCGGGCGACAACCAGCGCGTCGTGGACGCGGCGGCCGAACGGCTGGGGCTCGACGAGGCCCGGG
GCGACCTGCTGCCCAGCGACAAGGTGGACACCGTGCGGGCGCTCCGTCAGGACGAAGACGTGGCCATGGTGGGCGATGGG
GTGAACGACGCGCCCGCGATGGCGAACGCCACCGTGGGCGTTGCGATGGGGGCGGCGGGATCGGACGCGGCCCTGGAGAC
CGCCGACGTGGCCCTGATGGCCGACGACCTGTCCCAGCTGCCGTTCGCGGTGGGGCTCAGCCGACAGACCCGCCGCGTCA
TCACGCAGAACCTGTGGATTGCGCTCGGCATGGTGGCGGTGCTGGTGCCCGCTACGATTGCGGGGCTCTCCATCGGCCCG
GCCGTGGTGCTGCACGAAGGGTCGACGCTGCTCGTCGTGGGCAATGCGCTGCGGCTGCTCCGGTACACGCCGTCGTAA

Protein sequence :
MHSPSSSAVAEQVQLDLPVALPHVPDAMDACVDRLTDRLRGQPGVSRAHVVPATNGAPDRLCVHYDPDTIARSRIRRRVR
SVGADLTDRYGHLVWAVEGISRPRRARTIAKRLRQINGVVEAEARAAEQVRVEYDRSSTSAEEIRDVLRSMNVRPQGDRL
AAQGLAAEAGRGDREEEHDHDHGGIFGEKTELIVAVAAGVCVALGVGLSVVGGTPGWVPWGLYVGAYALGGYHTVREAVE
TLRAGEFEVDFLMLVAAGGAAVLGKWLEGAFLLFLFSLGHALEHYAMRRARRAIESLADLAPDTALVRRDGEEREVSVDQ
LRVGDTVIVKPNERIPADGFVTQGESAVNQAPVTGESVPVDKTPVETPAAARDPTTLDPAHRVYAGTINGSGVLEVRVTK
RAGESTLSRVVQMVTEAEAEKSPTERFTDRFERVFVPAVLGLVGLLLFAWVPLGEPVADSFYRAMAVLVAASPCALAIAT
PSAVLSALARAGQGGVLVKGGGPLEHLGRLGAVAFDKTGTLTEGAPRVTDVRPHNGTAEEDLLRAAVAAERLSDHPLAEA
VVQYGDEHLEGRPPEDAAEMRDITGRGIRASVGGRPVHVGNAALFDEVGGPPLPDPLRDEVEALEADGRTTMIVRRGDTY
LGVVGLADAPRPEAAGVVERLRRAGIRRMVMLSGDNQRVVDAAAERLGLDEARGDLLPSDKVDTVRALRQDEDVAMVGDG
VNDAPAMANATVGVAMGAAGSDAALETADVALMADDLSQLPFAVGLSRQTRRVITQNLWIALGMVAVLVPATIAGLSIGP
AVVLHEGSTLLVVGNALRLLRYTPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-96 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-96 42
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-95 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zntA YP_003569985.1 Cadmium-exporting ATPase BAC0124 Protein 3e-152 64
zntA YP_003569985.1 Cadmium-exporting ATPase BAC0298 Protein 3e-77 42
zntA YP_003569985.1 Cadmium-exporting ATPase BAC0092 Protein 3e-91 41