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Name : YPZ3_0228 (YPZ3_0228) Accession : YP_003566400.1 Strain : Yersinia pestis Z176003 Genome accession: NC_014029 Putative virulence/resistance : Virulence Product : secretion system apparatus protein Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4789 EC number : - Position : 262503 - 264551 bp Length : 2049 bp Strand : + Note : - DNA sequence : ATGAGTAAGTCAGCACTGGTGCGGGGTTTGACGATGATCACCGCGCGGCAGGATATTTTTTTAGCGGTCATGTTGCTGGT GGCGGTCTTTATGATGATCCTGCCACTGCCTACGACGATGGTGGATTTACTGATCGCCATCAATCTTGCCTTCTCCGTCA TTCTCTTAATGATCTCGATCTATCTGCGCGATCCTTTGGAGTTCTCCGTCTTCCCGTCATTACTGTTGATCACCACCCTT TATCGATTGGCACTGACGATCAGCACCACGCGACTGGTGCTGTTGCAACATGATGCCGGTGAGATTGTCGAGGCATTCGG TCAGTTTGTCGTGGGCGGTAATCTGGCCGTCGGGATGATCATTTTTACCATTATCACGGTGGTCCAATTTATCGTGATTA CCAAAGGTTCAGAGCGGGTTGCTGAGGTCAGTGCGCGCTTCTCACTTGATGGTATGCCGGGTAAGCAGATGAGCATCGAC GGCGACATGCGTGCGGGTGCGATCGATTCGGTCGAAGCTAAACGGCTACGGGAGCGGGTACAAAAAGAGAGCCGCTTATT TGGTGCTATGGACGGTGCCATGAAGTTTGTTAAAGGGGATGCCATCGCTGGGATCATTGTCATTCTGATCAATATCATTG GCGGTATCACTATTGGTGTGATGCAACACAAGATGTCCGCGGAAGAGGCGATGAATACCTACGCGGTATTATCGATAGGC GATGGATTGTGCGCCCAAATCCCTTCATTACTGATCTCGATTACCGCCGGGATTATTGTTACCCGGGTTCCTGGCAGCAA CAAACAGAGTCTGGCGAATGAGTTGGCGGTGCAGGTGGGGCGTCAACCGGATGCGCTGTGGTTAGCTGCCGCTATTCTGA CGGTGTTCGCCCTGTTACCCGGCTTCCCGTTCCTGATCTTTATCACTTTGGCGGCCGCGGTTGCGGCTCCGGCTTTTTTA CTTTATCGGAAGAACCGGCGGATATCGCAGGATGGTCGCGCAAATGGAGGCAGTGAAGAGGGGGGGGCCACGGGGCAGCG TATGACGCCTGGTGCCGTACCGCTGATGCTGCACTGTGCATCAAATTTACATCACCCGCATTTAGGGCGCGATATTGATG GCCTACGCTGGCGCTGGTTTGAGCATCTCGGTGTGCCATTGCCTGAGGTGGAGATCCGCTGTGATCCTACATTGGCAGAA AATACCTTATCGGTGCAGGTGTATCAGGAGCGGGTGCTGGAGGTTGTGTTACCGCCCGACAGCTTGTTACTGACACGGCC TTGCTCATCGTTAGTAACGAACAATCAGGTATTGGGCGCGAAGATGGGGTCATTTGATTGGCTGGATGCTAAACAGGCTA TGCAAGCCAGAACCTTGGGTATCCCTTACGTGGAGGGGCATCAGCGGATCATCACCTGTCTGACCAGGGTGTTTGAACGG TACACCGCCGAATTTATCGGCGTACAGGAGACTCGCTACCTGATGGATGCCATGGAAGGGCGCTATGGTGAGTTAGTGAA AGAGCTACAACGGCAGATACCCGTCGGTAAAGTGGCTGAAATATTACAACGGCTGGTTGAGGAAAATATTTCCATTCGCG ATTTACGGACTATTTTCGGCGCGTTGGTGGTTTGGGCACCGAAAGAAAAAGATATCGTGATGCTCACCGAATATGTCCGT ATCGCCTTGCGCCGTCATTTGTGCCGTCGCTTTAGTCACAATAAAACCTGGATATCAGTATTACGCCTCGGTGATGGGGT GGAGCATCTGATCCGCGACTCTATCCGCCAGACATCATCAGGCACTTACTCCGCACTGGAGGAGAGGCAATCCCTCTTGA TCCTCAACAAAATAAAAAACGCATTTGCTGAAAACCAGGATGCGGTATTGCTTACCACCCTCGATGTTCGTCGCTTTGTC CGCAAAATTATTGAGCGGGATCTCTTCGTGCTACCGGTACTTTCCTGGCAGGAACTGGGCGATGAAATGAATCTCAAGGT GGCGGGCACCATTGAACTGATTGGCGATGAACTTGATGAAACTGCCTGA Protein sequence : MSKSALVRGLTMITARQDIFLAVMLLVAVFMMILPLPTTMVDLLIAINLAFSVILLMISIYLRDPLEFSVFPSLLLITTL YRLALTISTTRLVLLQHDAGEIVEAFGQFVVGGNLAVGMIIFTIITVVQFIVITKGSERVAEVSARFSLDGMPGKQMSID GDMRAGAIDSVEAKRLRERVQKESRLFGAMDGAMKFVKGDAIAGIIVILINIIGGITIGVMQHKMSAEEAMNTYAVLSIG DGLCAQIPSLLISITAGIIVTRVPGSNKQSLANELAVQVGRQPDALWLAAAILTVFALLPGFPFLIFITLAAAVAAPAFL LYRKNRRISQDGRANGGSEEGGATGQRMTPGAVPLMLHCASNLHHPHLGRDIDGLRWRWFEHLGVPLPEVEIRCDPTLAE NTLSVQVYQERVLEVVLPPDSLLLTRPCSSLVTNNQVLGAKMGSFDWLDAKQAMQARTLGIPYVEGHQRIITCLTRVFER YTAEFIGVQETRYLMDAMEGRYGELVKELQRQIPVGKVAEILQRLVEENISIRDLRTIFGALVVWAPKEKDIVMLTEYVR IALRRHLCRRFSHNKTWISVLRLGDGVEHLIRDSIRQTSSGTYSALEERQSLLILNKIKNAFAENQDAVLLTTLDVRRFV RKIIERDLFVLPVLSWQELGDEMNLKVAGTIELIGDELDETA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| YPO0266 | YP_002345347.1 | secretion system apparatus protein SsaV | Virulence | Not named | Protein | 0.0 | 100 |
| ssaV | NP_456114.1 | putative type III secretion protein | Virulence | SPI-2 | Protein | 4e-160 | 58 |
| ssaV | NP_805085.1 | secretion system apparatus protein SsaV | Virulence | SPI-2 | Protein | 4e-160 | 58 |
| ssaV | CAA70536.1 | secretion system apparatus | Virulence | SPI-2 | Protein | 2e-160 | 58 |
| ssaV | YP_216422.1 | secretion system apparatus protein SsaV | Virulence | SPI-2 | Protein | 3e-160 | 58 |
| ssaV | NP_460379.1 | secretion system apparatus protein SsaV | Virulence | SPI-2 | Protein | 3e-160 | 58 |
| escV | YP_003236089.1 | putative translocator EscV | Virulence | LEE | Protein | 3e-126 | 49 |
| escV | CAI43875.1 | EscV protein | Virulence | LEE | Protein | 7e-127 | 49 |
| escV | YP_003223476.1 | translocator EscV | Virulence | LEE | Protein | 1e-126 | 49 |
| escV | AAK26714.1 | EscV | Virulence | LEE | Protein | 4e-127 | 49 |
| escV | YP_003232152.1 | T3SS structure protein EscV | Virulence | LEE | Protein | 5e-127 | 49 |
| escV | AAL57541.1 | EscV | Virulence | LEE | Protein | 4e-127 | 49 |
| escV | CAC81861.1 | EscV protein | Virulence | LEE II | Protein | 4e-127 | 49 |
| escV | AAC38382.1 | EscV | Virulence | LEE | Protein | 5e-126 | 49 |
| escV | NP_290269.1 | hypothetical protein | Virulence | LEE | Protein | 2e-125 | 49 |
| escV | AAC31514.1 | L0035 | Virulence | LEE | Protein | 1e-125 | 49 |
| ECs4569 | NP_312596.1 | hypothetical protein | Virulence | LEE | Protein | 2e-125 | 49 |
| escV | ACU09459.1 | EscV protein | Virulence | LEE | Protein | 1e-125 | 49 |
| escV | AFO66414.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 4e-121 | 49 |
| escV | AFO66296.1 | putative LEE-encoded type III secretion system factor | Virulence | SESS LEE | Protein | 3e-121 | 49 |
| unnamed | AAL06368.1 | EscV | Virulence | LEE | Protein | 4e-124 | 48 |
| lssD | AAO18050.1 | LssD | Virulence | TTSS locus | Protein | 4e-124 | 46 |
| invA | AAS66860.1 | InvA | Not tested | SSR-2 | Protein | 6e-88 | 42 |
| hrcV | AAT96193.1 | HrcV | Virulence | T-PAI | Protein | 3e-92 | 41 |
| hrcV | AAT96139.1 | HrcV | Virulence | T-PAI | Protein | 3e-92 | 41 |
| hrcV | ABA47273.1 | HrcV | Virulence | S-PAI | Protein | 2e-89 | 41 |
| ysaV | AAS66840.1 | YsaV | Not tested | SSR-1 | Protein | 1e-95 | 41 |
| hrcV | NP_791229.1 | type III secretion protein HrcV | Virulence | Hrp PAI | Protein | 1e-87 | 41 |
| hrcV | AAT96337.1 | HrcV | Virulence | S-PAI | Protein | 2e-87 | 41 |
| hrcV | AAT96297.1 | HrcV | Virulence | S-PAI | Protein | 4e-88 | 41 |
| hrcV | AAT96256.1 | HrcV | Virulence | S-PAI | Protein | 1e-88 | 41 |
| hrcV | AAR25631.1 | type III secretion protein HrcV | Not tested | Not named | Protein | 7e-84 | 41 |
| hrcV | AAB05999.2 | HrcV | Virulence | Hrp PAI | Protein | 3e-93 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0514 | Protein | 1e-160 | 58 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0729 | Protein | 3e-126 | 49 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0813 | Protein | 7e-126 | 49 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0064 | Protein | 9e-128 | 48 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0198 | Protein | 2e-107 | 45 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG0384 | Protein | 2e-120 | 45 |
| YPZ3_0228 | YP_003566400.1 | secretion system apparatus protein | VFG2126 | Protein | 5e-97 | 42 |
