Gene Information

Name : cadA (BMQ_0374)
Accession : YP_003560890.1
Strain : Bacillus megaterium QM B1551
Genome accession: NC_014019
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.-
Position : 348640 - 350559 bp
Length : 1920 bp
Strand : -
Note : -

DNA sequence :
ATGGAAAATGCGTTACCTAAAAAACAAGAACAAACGCCTCAAACATCTTCTGCTGTCAACGTATTAAAAACACATGGTGA
ACTCATTGCTGCACTGTTAAGCGGCGTGCTGATTTTAGCCGGCTGGCTGCTGTCAAAACAGCAGGATACTGCTGTATCTA
TTACGCTCTTTGTATTAGCTTACGTGATAGGCGGATTTGCTAAAGCAAAAGAAGGTATTGAAGAAACGATTGAAAATAAA
GAATTGAATGTCGAAATGTTAATGATTATTGCAGCCATTGGAGCGGCTGTAATTGGCTACTGGACAGAAGGTGCTATGCT
TATTTTCATTTTTGCATTAAGCGGTGCATTAGAAACGTACACCATGAATAAAAGCAACCGAGAAATTAGCGCCTTGATGA
ATTTACAGCCGCAAGAAGCAACGCGTCTGATTGGAGATCAAGAAGAAATTGTATCCATTTCGGATTTACAAATCGGTGAC
TTGCTGCTAGTTAAGCCGGGTGAACGAGTGCCATCCGATGGTATTGTTGTCTCAGGTCAAACAACGATTGATCAGGCTGC
TATTACAGGGGAATCTGTTCCTGTACTAAAACAGCTCGATGATGAAGTATTCGCGGGCACGGTGAATGTGAAAGGCGCCA
TTACCATTAAAATGACAAAGCCAAGTGCTGAGACGCTGTTTCAAAAGATCATTCAACTTGTTCAAACGGCTCAAAGTGAA
AAGTCGCCTTCTCAATTGTTTATTGAACGATTTGAAGGCACATACGTAAAAATTGTTCTATCGGTTGTGGCAGTTATGCT
ATTTCTCCCACACTATGTGCTTGGATGGAGCTGGACCGAGACATTTTACCGTGCAATGATTCTCTTAGTTGTAGCGTCTC
CTTGCGCTCTGGTTGCATCTATCACCCCTGCTTCGCTGTCTGCTATTTCAAACGGAGCAAAAAAAGGAATTTTGTTCAAA
GGCGGCGTGCATTTGGAAAGGTTAAGCCATTTAAGCGCAATTGCTTTTGATAAAACAGGAACGTTAACAAAAGGAAAGCC
AGAAGTAACAAATGTCATTGTCCGTTCTGATATGAACGAACAGGAATTTCTTGTTAAAATCGCATCAATTGAACGTCAGT
CCAATCATCCGCTTGCTCAATCCATTGTTGAATTTGTGAAAAATAAGCAGGAATTGACGCTCGTTCAGCCAGATTCGCTT
GAAGACGTTCCCGGATATGGTGTCATTGGGTCTCTTCAAGGAGATACGTGGAAGATAGGAAAAGCAGATTTTGTAGGTAA
AGAAGATGCAGCTGAATTTGAAAATGGGATTTCATCTACGCTTGCCAGTGAAGGAAAAACGATTGTGTACGCAAAAGACC
AGCATGGTATTGTGGGATTGCTTGCGCTAAAAGACGTTGTACGAACAGAAGCTGTAGACGCTGTTAAATCTCTTAAAGAG
CAGGGCATTCATACCGTCATGATTACAGGAGACAGCGAAAAAACAGCCGAAGCCATTTCAAAAGAATGTGCAGTTGATGA
ATACATTGCAGAATGTTTGCCTGAAGCGAAAGTAGATAAAATTAAAGCGTTAAAAGAAAAATTCCCTACCGTTTCAATGG
TGGGAGATGGCATTAACGATGCACCTGCTCTGGCTACTGCTAACGTTGGAGTAGCCATGGGAGAAGGAACGGATGTGGCA
CTTGAAACAGCGGATATCGTTTTAATGAAAAATGATCTATCAAAAATTTCGGATGCAGTAGCTCTTTCCAGACGGATGAA
CTCAATTGTGAAACAAAACGTTATTTTTTCTATTGCCGTCATCTTTTTATTAATTTGTTCGAATTTTTTCCAAGTACTTG
ATATGCCATTTGGTGTTATAGGTCACGAAGGCAGCACCATTTTAGTTATCTTAAACGGCCTTCGCTTGCTAAAATCTTAA

Protein sequence :
MENALPKKQEQTPQTSSAVNVLKTHGELIAALLSGVLILAGWLLSKQQDTAVSITLFVLAYVIGGFAKAKEGIEETIENK
ELNVEMLMIIAAIGAAVIGYWTEGAMLIFIFALSGALETYTMNKSNREISALMNLQPQEATRLIGDQEEIVSISDLQIGD
LLLVKPGERVPSDGIVVSGQTTIDQAAITGESVPVLKQLDDEVFAGTVNVKGAITIKMTKPSAETLFQKIIQLVQTAQSE
KSPSQLFIERFEGTYVKIVLSVVAVMLFLPHYVLGWSWTETFYRAMILLVVASPCALVASITPASLSAISNGAKKGILFK
GGVHLERLSHLSAIAFDKTGTLTKGKPEVTNVIVRSDMNEQEFLVKIASIERQSNHPLAQSIVEFVKNKQELTLVQPDSL
EDVPGYGVIGSLQGDTWKIGKADFVGKEDAAEFENGISSTLASEGKTIVYAKDQHGIVGLLALKDVVRTEAVDAVKSLKE
QGIHTVMITGDSEKTAEAISKECAVDEYIAECLPEAKVDKIKALKEKFPTVSMVGDGINDAPALATANVGVAMGEGTDVA
LETADIVLMKNDLSKISDAVALSRRMNSIVKQNVIFSIAVIFLLICSNFFQVLDMPFGVIGHEGSTILVILNGLRLLKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 1e-104 43
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 9e-105 43
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-95 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_003560890.1 heavy metal translocating P-type ATPase BAC0092 Protein 2e-133 48