Gene Information

Name : Amico_0449 (Amico_0449)
Accession : YP_003553314.1
Strain : Aminobacterium colombiense DSM 12261
Genome accession: NC_014011
Putative virulence/resistance : Unknown
Product : N-6 DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 479467 - 480948 bp
Length : 1482 bp
Strand : +
Note : PFAM: N-6 DNA methylase; KEGG: afr:AFE_2793 type I restriction-modification system, M subunit

DNA sequence :
ATGTCTGTGAACTTGGAATTTGAAGATAAATTATGGGAAATGGCAGATAAACTGCGAGGCAATATTCAGCCTTCAGATTA
TAAGGATGTTGTTCTTGGTCTTATCTTTTTGAAATATATCTCTGATAGTTTTGAAGAAAAATACAACGAACTGGTAGCAG
AAGAAGAAGGTTTCGAAGAAGACAGAGATGCCTACGTAGCAGAAAACATTTTTTATGTTCCACCCAGCGCCAGGTGGGAT
TTTATTAAAAAGAATGCGAAACAGAGCACCATTGGACAAATTATAGATGATGCCATGATAACTATTGAACGAGAAAATAG
AAACCTAAAAGGAGTCCTTCCCAAAAATTACGCGAGGCCTGAGCTTGATAAAGCAAAATTAGGAGAGCTCGTTGATTTGT
TTTCCTTCAACCTCGGAAACAAAGAAGCCAAAGCTCAAGATATTCTAGGCAGGGTATATGAGTATTTCTTAGGGAAATTC
GGTTCCAGCGAAGGTGAATTTTATACGCCGCCTAGCATCGTAAAACTTCTAGTTGGCATGATTGAACCGTATAAAGGAAG
AGTTTATGACCCTTGTTGCGGTTCTGGCGGCATGTTTGTGCAGTCATCCCGTTTTGTTGAAGAGCACCAGGGGCGAAAAG
ATGATATCCACATCTTCGGTCAAGAATATACGGCTACGACCTGGAGACTTTGCAAAATGAATCTGGCTATCAGGGGAATT
GATGGAAATCTTGGAGCGCGAGACGCAGATACATTTGGAAATGATCTGCATAAAAATATAAGAGCCGATTATATCTTGGC
TAATCCTCCTTTTAATGTTAGCGATTACACCTTAATTCCAGATGATGCCCGTTGGAAATATGGAATTCCGCCAGAAAAGA
ACGCCAACTACGCCTGGATTGAACATATTATCAGCAAACTTTCTCCTACCGGAGTGGCGGGCTTTGTCTTGGCTAACGGA
TCTATGAGTACAACCACTAAAGCCGAAGCGGAAATAAGAAAGAACATCATAGAAGCAGGACTTGTAGATTGCATTGTTAC
TATGCCACCAAACCTTTTTTACAATGTAACCATTCCTGTTTGTCTGTGGTTTATCTCTAAAAAGCGAGAAAACAAGCAAG
ATAAAATTCTCTTTATTGATGCTCGTAAAATGGGAACAATGGTTACCCGCAAGCATAGAGAATTTTCTGATGGAGAAATA
GCAAAGATCTACGACACCTACCACAACTGGCGCGATAATAAAAAAGAATATAAAGACATACAGGGTTTTTGCAAATCTGC
CGATATTGAAGAAGTAAGAGAGCACGAATATATACTGACTCCTGGCCGATATGTGGGCATAGAAGAAGTGGAAGACGACG
GCGAACCCTTCGAAGAGAAGATGACGCGGCTAACAGGTGAACTGGCAGAGATGTTCGCTAAATCCCACAAACTAGAAGAA
GAGATCAAGCAGCGATTAGGAGCGATTGGTTATGAGTTCTAA

Protein sequence :
MSVNLEFEDKLWEMADKLRGNIQPSDYKDVVLGLIFLKYISDSFEEKYNELVAEEEGFEEDRDAYVAENIFYVPPSARWD
FIKKNAKQSTIGQIIDDAMITIERENRNLKGVLPKNYARPELDKAKLGELVDLFSFNLGNKEAKAQDILGRVYEYFLGKF
GSSEGEFYTPPSIVKLLVGMIEPYKGRVYDPCCGSGGMFVQSSRFVEEHQGRKDDIHIFGQEYTATTWRLCKMNLAIRGI
DGNLGARDADTFGNDLHKNIRADYILANPPFNVSDYTLIPDDARWKYGIPPEKNANYAWIEHIISKLSPTGVAGFVLANG
SMSTTTKAEAEIRKNIIEAGLVDCIVTMPPNLFYNVTIPVCLWFISKKRENKQDKILFIDARKMGTMVTRKHREFSDGEI
AKIYDTYHNWRDNKKEYKDIQGFCKSADIEEVREHEYILTPGRYVGIEEVEDDGEPFEEKMTRLTGELAEMFAKSHKLEE
EIKQRLGAIGYEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-161 65
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-160 64
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 2e-160 64
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-107 43