Gene Information

Name : Amico_0398 (Amico_0398)
Accession : YP_003553265.1
Strain : Aminobacterium colombiense DSM 12261
Genome accession: NC_014011
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 426747 - 429791 bp
Length : 3045 bp
Strand : +
Note : PFAM: acriflavin resistance protein; KEGG: vsp:VS_1986 cation/multidrug efflux pump

DNA sequence :
ATGAATATTGCAGAATATTCAATTCAAAAGAGATACGTGACGTGGTTTTTTACAGTTTTTTTGATTATAGGTGGAGTTTT
TGCCTATAAAGGATTAGGAAAACTGGAAGATCCTGCCTTTACTATTAAGACCGCAGTAGTTACCACTGCTTATCCAGGAG
CTACGCCAAAAGAAGTGGAGGAAGAGGTAACGGAAGTTATAGAACGGGCTGCTCAACAGATGGGACAAGTGGATAAGGTC
CGGTCTCTTTCTCAGGAAGGCGTTTCTCTTGTGTATGTAGATATTAAAGATACGTATACAGCAAAAGATTTGCCTCAAAT
ATGGGACGAGTTACGACGGAAAATAAATGATGTTCAAGAGCATTTGCCACCAGGAACAAGTCGTTCTTTAGTTAACGATG
ACTACGGAGATGTATATGGAGTTTATTTTGCCCTTACTGGCGAAGGATATTCTTACAGAGAACTTGAAGATTTTGCCGAT
TATCTGCGTAGGGAGTTGCTCCTTGTTCCTGGGGTTGCAAGTGTTGAAGTGACAGGCATACAAAAAGAGGCTATTTATGT
AGAAATTTCCAGAACGAAACTTAGTCAGCTCGGTATCTCTATGGGAGAACTTTTTCAAGTTCTCAAAGCTCAGAATTTCG
TGGTTCCATCGGGGAAAGTGAGAGCGGGGGCAGAGTATATTCGCATAACTCCAACTGGGGAGTTTTCTTCTGTCGAACAA
GTAGGGGCGTTACTTCTTGCATCTTCCTCGAGGGTGCTGATCCGTTTAGATGACATAGCTACAGTTACTCGTAATTATAT
AGAGCCGACACGGGCAATTATGCGTTATAACGGAAGTCCTGCTGTTGGAATCGGTATCTCCAACGTAGAAGGTGGCAACG
TTATTGCTATGGGAGAAGCCATAAAGAAGCGGCTCAAGGAACTAGAGCCGCAGACTCCTATCGGCATGAATTTAGGGCTT
ATTTACTACCAGTCGGATACAGTTCAAAAGGCAATTAATAACTTTTTATTAAATCTTCTGGAAGCTCTGAGTATAGTTAT
TGCCATATTACTTATATTTATGGGTTTCCGCAGTGGGATGCTTATTGGCGGGGTATTGTTGCTTACAATTTTTGCCACTT
TTATCGCAATGAAACTTGTGAGGATAGATCTTCATAGTATTTCTCTTGGAGCATTGATTGTAGCTTTGGGAATGCTAGTG
GACAACGCCATCGTTGTTGCTGATGGCCTTCTTGTGCGGATACAAAGTGGTGAGGATAGAATATCTTCTGCCGTGGGTGT
TGTGACTCAAACTCAATGGCCTTTGTTGGGAGCTACTTTTATTGCTGTTATAGCTTTTGCTCCTATTGGCCTGTCCCCAG
ATAGCACAGGGGAGTTTTGCCAAAGCCTTTTTCAGGTGGTGGGGATTTCCTTGATTATAAGTTGGGTGCTTGCCGTTACC
GTTACTCCTGTAGCCGGTGTGCGTTTTTTAAAAACTTCAGCAAAAGCAGAAATTCCCTACGATACAAAACTTTATAGGGT
GTATAGAAGATTTCTCAAGGCGTGTATTCGTAAGAGAAAGGTAACAATATTGGTTATGGTTTGTTTGCTTGGTTCTGCTC
TCATAGGCTTTACGTTTGTGGATCAATCTTTTTTCCCAAGCTCCTCAAGCCCCCTTTTTACAGTGGAATTTTGGCGTCCT
CGGGGTGCTTATATAGAAGAGACCCAGAGAGAGGTAGAAAAAGTTGAAGCTTTTATTTTGAAACAGCCAGAGACAGTTTC
TGTAGCAAGCTACGTGGGACAGGGAGCCCTTCGTTTTATTCTCACCTATACGCCAAGTGATTCTTCTGATAGTTATGGAC
ACTTGATAGTGGAAGCTAAGGATTTGAAATCAGCAGAGTCTTTACGTCGTAAACTGGGAAATTTCATGAATATAGAAATG
CCAGATATCGACCCCAGGGTTCGTTCCTTTAGTAAAGGAACAGGGGGAGGTGCAAAAATACAGGCGAGGTTTACGGGGGA
CGATCCTCGTGTTTTACGACGTCTAGGAGAAGAAGCTTTTTATATGATGAGGAACGCCCCCGATTCGATGAACATCCGGA
GCGACTGGGGAGAAAGGGTCAAGGTTATTCGTCCCGTACTTGATGAGGTGCGAACCCGACAAGCTGGTTTAACACGGCAA
GATGTAGCATCGGCCCTTGAGATGTCCTTTTCGGGTATACAAGCAGGCTTATACAGAGAGAGGGATAAACTCCTCCCTAT
TATAGCTAGATTGCCTAAAGCGGATAGGGCGAGACTGGGGGCACTTCCAGAAGTAGAAGTGTGGAGCCCCCTTATGAGAA
AATATATAGCCTTAACTCAGATTACAAAAAGCATTGATACCATAGCTGAAGACCCCGTTATTTATAGGCGAAATCGTATG
AGGACTTTTTCTGTAGAGTGTGATTCCCGTTCTGGGAAAACAGGTCTTTTATTTGCTCGTATAAAGCCCGAACTGGAAAA
TATTTCTCTTCCTTTAGGATATAGCCTCAGTAGGGGAGGCGAGTATGAAAGTTCTCAAAAAGCTCAAGGTGGACTTGTGG
GGATGATTCCTATTGCTTTTTTAGCCATGGTCGCTATATTAGTTGTTCTTTTTAACGGGTTTAAACAACCCATTATGATC
CTTCTTTGTCTCCCCTTGTCCATTATTGGTGTAACGGCGGGATTACTTCTTTTTCATAAATCTTTTGACTTTATGGCTCT
CCTGGGATTCTTGAGCCTTGCTGGCATGCTCATAAAAAATGCCATTGTGCTTATTGATCAGATCGATCTCGAAATACGGG
AAGGAAAAGAGGGCTTTTCAGCTATAGTGGATTCGGCTATGAGTCGTGCTCGTCCTGTTCTTATGGCAGCTATTACCACG
GTTTTAGGTATGATCCCTCTTTATTTTGATATTCTCTTTTCTGCTCTGGCAGTTACTATTATGTTTGGCTTGGCTTTTGC
CACGGTTTTGACGTTAATTATCGTACCAGTTCTTTACTCTGTTTTTTTAAAAATTCCTGTTTTTAAAGACGAAAATGTTA
GGTAG

Protein sequence :
MNIAEYSIQKRYVTWFFTVFLIIGGVFAYKGLGKLEDPAFTIKTAVVTTAYPGATPKEVEEEVTEVIERAAQQMGQVDKV
RSLSQEGVSLVYVDIKDTYTAKDLPQIWDELRRKINDVQEHLPPGTSRSLVNDDYGDVYGVYFALTGEGYSYRELEDFAD
YLRRELLLVPGVASVEVTGIQKEAIYVEISRTKLSQLGISMGELFQVLKAQNFVVPSGKVRAGAEYIRITPTGEFSSVEQ
VGALLLASSSRVLIRLDDIATVTRNYIEPTRAIMRYNGSPAVGIGISNVEGGNVIAMGEAIKKRLKELEPQTPIGMNLGL
IYYQSDTVQKAINNFLLNLLEALSIVIAILLIFMGFRSGMLIGGVLLLTIFATFIAMKLVRIDLHSISLGALIVALGMLV
DNAIVVADGLLVRIQSGEDRISSAVGVVTQTQWPLLGATFIAVIAFAPIGLSPDSTGEFCQSLFQVVGISLIISWVLAVT
VTPVAGVRFLKTSAKAEIPYDTKLYRVYRRFLKACIRKRKVTILVMVCLLGSALIGFTFVDQSFFPSSSSPLFTVEFWRP
RGAYIEETQREVEKVEAFILKQPETVSVASYVGQGALRFILTYTPSDSSDSYGHLIVEAKDLKSAESLRRKLGNFMNIEM
PDIDPRVRSFSKGTGGGAKIQARFTGDDPRVLRRLGEEAFYMMRNAPDSMNIRSDWGERVKVIRPVLDEVRTRQAGLTRQ
DVASALEMSFSGIQAGLYRERDKLLPIIARLPKADRARLGALPEVEVWSPLMRKYIALTQITKSIDTIAEDPVIYRRNRM
RTFSVECDSRSGKTGLLFARIKPELENISLPLGYSLSRGGEYESSQKAQGGLVGMIPIAFLAMVAILVVLFNGFKQPIMI
LLCLPLSIIGVTAGLLLFHKSFDFMALLGFLSLAGMLIKNAIVLIDQIDLEIREGKEGFSAIVDSAMSRARPVLMAAITT
VLGMIPLYFDILFSALAVTIMFGLAFATVLTLIIVPVLYSVFLKIPVFKDENVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amico_0398 YP_003553265.1 acriflavin resistance protein BAC0519 Protein 0.0 48
Amico_0398 YP_003553265.1 acriflavin resistance protein BAC0428 Protein 0.0 48
Amico_0398 YP_003553265.1 acriflavin resistance protein BAC0526 Protein 0.0 46
Amico_0398 YP_003553265.1 acriflavin resistance protein BAC0425 Protein 0.0 44