Gene Information

Name : Mmah_2019 (Mmah_2019)
Accession : YP_003543157.1
Strain : Methanohalophilus mahii DSM 5219
Genome accession: NC_014002
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 1994460 - 1997105 bp
Length : 2646 bp
Strand : -
Note : COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR007860:IPR000432:IPR007861:IPR007696:IPR 007695:IPR005748; KEGG: gme:Gmet_1424 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS; MutS II domain protein; MutS IV domain

DNA sequence :
ATGAGCAAGATTACACCTGCGATGCAACAGTATTATGCTGCCAAGGAGCAACATCCCGATTCCCTGATATTCTTCCGTAT
GGGGGATTTCTATGAATCCTTCGGGGAGGATGCAAAGACCATCGCACAGGAACTTGACATAACTCTCACCACCCGGGGTA
AGGGAAAGGACGGGGAAAAAATGCCCCTGGCTGGAATTCCCTATCATGCGGTGGATAATTACCTGCCCAGACTGGTCAGG
AAAGGCTACAAGGTCGCGGTATGTGAACAGCTTGAAGACCCCAAAAACGCGAAAGGGGTTGTCAAACGGGGAGTGGTGCG
TGTGGTCACCCCCGGGACAGTTATCGATTCCTCCATGCTTTCTGATCCATCAAACAACTACCTGATGGCGATTGCCGGCA
GGGATAAGGATTTTGGCGTGGCTTTTTTGGATGTATCCACAGGAGAATTCCTGACTACCCAGATCAACGATCAACCTCCC
TTTGACGGGATTGCGGGAGAGGTGGCACGAATGCGGCCTGCAGAATGTATTGTCCTTCCCCAATTAATGGAAAATGAGGA
ATTACAAAGCAGGTTGGCAGAGTTGAAACTCTCCACAACTGAATTTGATGCTGCTTCCACGGACCCGGCCTATGCGGACA
GACATCTATGCGAGCATCTGGGTGTCTCCACCCTGGAAGGTATGGGTTGTGCCGGGCTTCCCTTTGCAAAAATGGCAGCC
AGCTGTGCCCTGGAATATGCCCTGGAAACCCAGATGCGTGAATTAAATCATGTTCAGTTCCTCCATACCTATTCCTCCTC
CGAATTCATGATACTGGATTCAATTACGCTGCGTAATCTGGAGGTTGTGAAAAATGTCAGGGGAGAGGGAAGGGATACAA
CTATTCTCCAGGTACTGGATGAGACCAAAACGCCAATGGGCAGCCGTCTGCTTCAGAAATGGATCCTCAAACCCCTGCTT
AATGTCTCCCATATAAATAAGCGGCTGGATGCCGTGGAAGAATTGTCCGATAACACCCTGTTGAGATTTGATGTGCGCTC
CCATCTTTCCTATGTAAAGGATGTGGAGAGACTTGTGGGCAGGGTGGTTTATGGCAACTCCAATGCCAGGGACCTTGTAG
CCCTCAAAAAATCCCTCCAGGCGATACCATCGCTGCTAGAAACCCTGGAGGGGGAACATAAGGCAATGCTTGCCCGGATA
GTGCAGGGAATGAAGGATTTCAGGGAAATAGATACTCTCACTGACCTGATCGAGCGGGCTATCGTGGAGGAGCCTCCTCT
GTCCGTGCGGGAGGGCGGGCTGATCAAACCCGGCTATAGTGAGGAACTGGATGAACTGAAGGAAATTTCCAGTAATGCCA
AATCCTGGATTGCCTCATTCCAGCAGAAGGAGAGGGACAGGACCGGGATCAAATCCCTCAAGGTAGGCTACAACAAGGTG
ATAGGTTATTATCTGGAGGTTACCAAGCCCAATATTTCCCAGGTGCCTGATGATTACATCCGCAAACAGACAATGACCAA
TGCCGAGCGTTTCTACACCCCACAGCTCAAGGACTGGGAAGGCAAAATCCTGTCTGCAGATGAGAAAAGGGTGGCACTGG
AATATGAACTGTTCAATGAAGTTATATCGGTGGTAGCAAATCATTCGAAACAGTTGCAGGAGATGGCAGTCCTGCTGGGA
GAGCTGGACGTGTTGGCTTCCCTTGCAGAGGTTGCGGTGAACAATAATTATGTGCGTCCTTCCATTACCGATGACTGCAG
GATACTGATACGCCAAGGCAGGCATCCTGTTGTGGAAAATTCGGTAGATGGAGGATTCATTCCCAATGACGTGGAAATGG
ATTGTTCTGATGAGCAGTTCCTTCTGATCACGGGCCCCAATATGGCTGGTAAATCCACCTATATGAGACAGGTTGCCCTG
ATAGTCATAATGGCCCAGGCGGGATCCTTTGTACCCGCTTCCCATGCATCGGTGGGTATAGTGGACAGGATATTCACCCG
GGTGGGGGCCTTTGATGACCTGGCAAGCGGGCAGAGTACCTTCATGGTGGAGATGGTGGAACTTGCCAATATCCTGAATA
ATTCCACTGCGAAAAGCCTGGTGCTTCTGGATGAGATCGGCAGGGGGACCAGTACCTATGATGGTTACAGTATAGCCAAG
GCCGTTGTGGAGTATATCCATAACAAGGGTCGCCAGGGAGTACGTTCCCTTTTTGCTACCCATTATCACCAGCTGACCGA
AATTGCCGAATCGCTCAAGAGGGTTAAGAATTATCATATAGCGGTCAAGGAGGACGGGGATGATCTGGTATTTTTGCGCA
AGATCGTGCCCGGTGCAACTGACAAAAGTTACGGTATCCATGTGGCCAGGCTTGCAGGTGTTCCTCATAAGGTGACCAAA
AGGGCGCAGTCGATCCTGGAAGATATTGAAAGTGAGAGTGTGATCAGCAGGGAAAGTGAAGGTTCCAGAAAACGCAGGAG
TGGTGCCAAATATACCCAGCTTTTGCTGGTAGATCCGGAAAAAGGTGATGAGAAAGATTTTGATCCGGTTGCAGAGGAAA
TAAGGGACCTGGATCTCAATAACCTCACTCCAATGGAAGCCCTGAACAGACTGCATGCTATACAGCAAAAACTGAAGGAG
AGTTGA

Protein sequence :
MSKITPAMQQYYAAKEQHPDSLIFFRMGDFYESFGEDAKTIAQELDITLTTRGKGKDGEKMPLAGIPYHAVDNYLPRLVR
KGYKVAVCEQLEDPKNAKGVVKRGVVRVVTPGTVIDSSMLSDPSNNYLMAIAGRDKDFGVAFLDVSTGEFLTTQINDQPP
FDGIAGEVARMRPAECIVLPQLMENEELQSRLAELKLSTTEFDAASTDPAYADRHLCEHLGVSTLEGMGCAGLPFAKMAA
SCALEYALETQMRELNHVQFLHTYSSSEFMILDSITLRNLEVVKNVRGEGRDTTILQVLDETKTPMGSRLLQKWILKPLL
NVSHINKRLDAVEELSDNTLLRFDVRSHLSYVKDVERLVGRVVYGNSNARDLVALKKSLQAIPSLLETLEGEHKAMLARI
VQGMKDFREIDTLTDLIERAIVEEPPLSVREGGLIKPGYSEELDELKEISSNAKSWIASFQQKERDRTGIKSLKVGYNKV
IGYYLEVTKPNISQVPDDYIRKQTMTNAERFYTPQLKDWEGKILSADEKRVALEYELFNEVISVVANHSKQLQEMAVLLG
ELDVLASLAEVAVNNNYVRPSITDDCRILIRQGRHPVVENSVDGGFIPNDVEMDCSDEQFLLITGPNMAGKSTYMRQVAL
IVIMAQAGSFVPASHASVGIVDRIFTRVGAFDDLASGQSTFMVEMVELANILNNSTAKSLVLLDEIGRGTSTYDGYSIAK
AVVEYIHNKGRQGVRSLFATHYHQLTEIAESLKRVKNYHIAVKEDGDDLVFLRKIVPGATDKSYGIHVARLAGVPHKVTK
RAQSILEDIESESVISRESEGSRKRRSGAKYTQLLLVDPEKGDEKDFDPVAEEIRDLDLNNLTPMEALNRLHAIQQKLKE
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 7e-129 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mmah_2019 YP_003543157.1 DNA mismatch repair protein MutS VFG0562 Protein 2e-145 43