Gene Information

Name : invA1 (EAMY_0779)
Accession : YP_003530137.1
Strain : Erwinia amylovora CFBP1430
Genome accession: NC_013961
Putative virulence/resistance : Virulence
Product : type III secretion apparatus protein InvA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 866544 - 868541 bp
Length : 1998 bp
Strand : +
Note : type III secretion apparatus InvA, FHIPEP family, HrcV/FlhA family

DNA sequence :
ATGATAGTAGTCATGCTTATTATTCCGTTGCCGACCTATATTGTCGATTTTCTGATTGGTCTTAATTTGACCATGGCGTT
ATTGATTTTCCTTGGCTCATTTTATATTAATCGCGTTCTTGATTATTCGACGTTTCCGTCAATTCTCCTGATTAGTACGA
TTTTCAGACTGGCCATTTCTATCAGCACCAGCAGACTGGTACTTACTGATGCCGATGCCGGAGAAATTATTACCAGCTTT
GGTGAGTTCGTTATCGCTGATAATATGGTTGTGGGCTTCGTTATTTTCTTCATCGTCACGGTTGTTCAGTTTATCGTGAT
TACCAAAGGATCTGAACGTATTGCAGAAGTTGCCGCTCGTTTCTCTCTGGATGCTATGCCCGGTAAGCAGATGAGTATTG
ATGCTGATCTTAAAGCCGGCGTGATTAATGAAAAAGAAGTGAAGCGGCGTCGAAGTGACCTGGAAGCCGAAAGCCAGCTT
TACGGTGCGCTGGATGGTGCGATGAAGTTTATCAAAGGTGATGCCATCGCTGGGATAATTATCATCTTCGTCAACTTTCT
GGGTGGGATCTCAGTCGGGGTTTTCCAGCAAGGCATGGATGTATCTCATGCTATGTCGGTCTTTACGTTGCTAACCATCG
GTGATGCTCTGGTAGCTCAGATACCGGCATTACTGATCTCAATCAGTGGCGGCCTGATTGTTACCCGTGTGAATAACAGT
GATAACAATAATCTGGGATCAAAAATCCTGCAGGATATGCTTTCTAACAAGTCTATTCTGCTAATCACAGCTTTTCTCGC
TATTGCACTAGGGCTGCTGCCTGGTTTTCCTTTGCCCGTATTCATCTTATTGGCAATCCCCCTTTTGGGAATGTTCGTAA
AACACAAATTTGATGAGAAGAATAAAATTGTTAAAGCGGGAGAAGAAAATCTTCAAGATGATGATCAGCCGGTGCTGAAG
AGCAAGCCAGTTATTATTGATGGTGAGTACATTCCAGAAACTATCCCGCTTATCATCACCGCCTGGAAAGGATATGAACA
ATATTTCCAGGAACATAATTTTACATCGTTATTTAAACGTAATTTCTTCGTAGAATATGGTGTTCGCCTGCCGGAAGTTT
TAATGAATTATGAAGAGAGCGCCCCGCGCGGCATTCTGACGGTAGCCATTAATGAAATACAGGTGGCATCTTACAATATA
TTTCCGGGCATGTGTAAGGTATTAATGCAGGGTGAGGAACTTCAGGTGATTGATGCCAGCGTTCAGACGATTGCATCCCC
ACAGGGAAACGTCTATTGGCTACCTGAGGAACGGAATGAGAAAGCCATCCAGCTGGGGTATCATACAAGAAACGCGATAG
ATGAGTTTTACGCATGTGTTTCTACTTTGCTTGTTCATAATATCTCAGAATTTTTTGGTATTCAGGAGACCAAAACGCTG
CTTGATGACCTTGAAAAGAAATATCCCGATCTTCTTAAGGAATGCTACCGTAATAACACCGTCCAACGTATTACGGAAGT
CTTTCAGAGGCTCCTTCAGGAACGTATCTCAATCAGAAATATGCGACTAATTCTGGAAGCGTTGGTGCAATGGGCTCCAA
AAGAGAAAGATCCGATTATGTTAGTCGAGCACGTCAGAGGGGTTTTGGCCCGGTACATCTCTAACCGCTTTGCTTTTCGT
GGACGTATAAGAACGTTGGTTATGTCACATGATATGGAAAATATGATTCGCGGTGCGCTAAGGCAAACCTCATCGGGTAC
TTTTATAAATTTACCACCACCGCAAATTGAAAGTGTAAATAAATGTCTGGAAGAAGTTCTTCAACTCAATGGTGTTAATG
CTCGGGATATCATCTTGATGGTGTCAATGGATATCAGGCGTTTCGTTAAGAAAATTACCGAGGGAAATAACCCTGAGATG
GAAGTGCTTTCTTACGGTGAGATTTCTACCGGTGTAGAAGTGGATGTTATAGGCTCTTTAGAAAATAATCAGGTGTAA

Protein sequence :
MIVVMLIIPLPTYIVDFLIGLNLTMALLIFLGSFYINRVLDYSTFPSILLISTIFRLAISISTSRLVLTDADAGEIITSF
GEFVIADNMVVGFVIFFIVTVVQFIVITKGSERIAEVAARFSLDAMPGKQMSIDADLKAGVINEKEVKRRRSDLEAESQL
YGALDGAMKFIKGDAIAGIIIIFVNFLGGISVGVFQQGMDVSHAMSVFTLLTIGDALVAQIPALLISISGGLIVTRVNNS
DNNNLGSKILQDMLSNKSILLITAFLAIALGLLPGFPLPVFILLAIPLLGMFVKHKFDEKNKIVKAGEENLQDDDQPVLK
SKPVIIDGEYIPETIPLIITAWKGYEQYFQEHNFTSLFKRNFFVEYGVRLPEVLMNYEESAPRGILTVAINEIQVASYNI
FPGMCKVLMQGEELQVIDASVQTIASPQGNVYWLPEERNEKAIQLGYHTRNAIDEFYACVSTLLVHNISEFFGIQETKTL
LDDLEKKYPDLLKECYRNNTVQRITEVFQRLLQERISIRNMRLILEALVQWAPKEKDPIMLVEHVRGVLARYISNRFAFR
GRIRTLVMSHDMENMIRGALRQTSSGTFINLPPPQIESVNKCLEEVLQLNGVNARDIILMVSMDIRRFVKKITEGNNPEM
EVLSYGEISTGVEVDVIGSLENNQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 0.0 68
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 9e-139 53
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 9e-139 53
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 9e-139 53
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 9e-139 53
ECs3731 NP_311758.1 EivA Not tested LIM Protein 5e-134 53
invA AAS66860.1 InvA Not tested SSR-2 Protein 2e-123 50
escV NP_290269.1 hypothetical protein Virulence LEE Protein 1e-83 41
escV CAC81861.1 EscV protein Virulence LEE II Protein 6e-85 41
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 1e-83 41
escV AAC31514.1 L0035 Virulence LEE Protein 9e-84 41
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 2e-84 41
escV ACU09459.1 EscV protein Virulence LEE Protein 9e-84 41
escV YP_003223476.1 translocator EscV Virulence LEE Protein 1e-84 41
escV AAC38382.1 EscV Virulence LEE Protein 7e-84 41
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 7e-85 41
escV AAK26714.1 EscV Virulence LEE Protein 1e-84 41
escV AAL57541.1 EscV Virulence LEE Protein 1e-84 41
escV CAI43875.1 EscV protein Virulence LEE Protein 9e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
invA1 YP_003530137.1 type III secretion apparatus protein InvA VFG1780 Protein 4e-151 55
invA1 YP_003530137.1 type III secretion apparatus protein InvA VFG0557 Protein 4e-139 53
invA1 YP_003530137.1 type III secretion apparatus protein InvA VFG1006 Protein 1e-123 50
invA1 YP_003530137.1 type III secretion apparatus protein InvA VFG0729 Protein 4e-84 41
invA1 YP_003530137.1 type III secretion apparatus protein InvA VFG0813 Protein 5e-84 41