Gene Information

Name : intB (EAMY_0383)
Accession : YP_003529741.1
Strain : Erwinia amylovora CFBP1430
Genome accession: NC_013961
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 445798 - 447075 bp
Length : 1278 bp
Strand : +
Note : DNA breaking-rejoining enzyme, catalytic core, Phage integrase family

DNA sequence :
ATGGCTCTAACAGATATTAAAGTCAGAACAGCCAAGCCTACGGATAAGCAATATAAGCTGACTGATGGCAACGGTATGCA
TCTTCTCGTCCACCCAAATGGTTCAAGATACTGGCGTCTGCAGTACCGCTTTGGCGGGAAGCAAAAGATGCTGGCTTTAG
GCGTATATCCTGATGTGTCTCTTGCAGATGCCAGAGCTCGTCGCGATGAAGCACGTAAGCTTTTGGCAAACAGCATCGAT
CCGGGAGACAAAAAGAAAAATGATAAGGTTGAACAGGAAGAAGCGCGCACTTTTGAGGAGCTTGCTGTTGAGTGGCACGC
TACAAATAAAAAGTGGTCGGAAGAACATAGCCGACGAGTATTAAAAAGCCTGGAGGACAACCTCTTTCCTGCCATTGGCA
AACGTAATATTGCTGAACTAAAAACGAGAGATCTGTTAGCACCAATTAAAGCCGTGGAGATGTCTGGACGTCTTGAAGTG
GCATCGCGTCTACAGCAGCGCACTACTGCAATTATGAGATATGCCGTTCAGAGTGGTTTACTTGATTACAATCCCGCACA
GGAAATGGTTGGTGCTGTTGCTTCAAGTAACAGGCAGCATAGACCTGCATTGGAGTTGAAACGTACCCCCGAACTGCTTC
AGCGCATAGACAGCTATACCGGTAGACCTTTGACCTGCCTTGCCGTTGAGCTAACCCTCCTTGTATTTATTCGTTCAAGT
GAACTGCGTTTTGCTCGTTGGTCTGAGATCGATTTTGAAACATCGATGTGGATGATTCCTGCCGAGCGAGAAGCTATTGA
GGGAGTAAAGCACTCACAGCGAGGTTCGAAAATGCGGACACCTCATCTGGTTCCACTTTCCCGACAAGCTCTGGCGATTC
TTGAGCAGATAAAAACGTTCAGCGGTGATCATGAACTGATCTTTATTGGCGATCATAACCCTCGCAAACCGATGAGTGAA
AACACAGTTAACAAGTCATTGCGAGTAATGGGATATGACACACAAATTGAAGTGTGCGGCCACGGTTTCAGGACCATGGC
ATGTAGTTCGTTGATTGAGTCAGGATTGTGGTCGAGGGATGCCGTAAAACGACAGATGAGCCATATGGAGCGTAACTCTG
TGCGTGCGGCTTACATTCATAAGGCCGAGCATCTGGATGAGCGCAAGCTAATGCTGCAATGGTGGGCTGACTTCTTGGAT
GCGAATCGGGAGAAGGCGGTGAGTCCGTTTGATTTTGCGAAGATTAACACATCGATAAAAATTCAGAATGGCTTATGA

Protein sequence :
MALTDIKVRTAKPTDKQYKLTDGNGMHLLVHPNGSRYWRLQYRFGGKQKMLALGVYPDVSLADARARRDEARKLLANSID
PGDKKKNDKVEQEEARTFEELAVEWHATNKKWSEEHSRRVLKSLEDNLFPAIGKRNIAELKTRDLLAPIKAVEMSGRLEV
ASRLQQRTTAIMRYAVQSGLLDYNPAQEMVGAVASSNRQHRPALELKRTPELLQRIDSYTGRPLTCLAVELTLLVFIRSS
ELRFARWSEIDFETSMWMIPAEREAIEGVKHSQRGSKMRTPHLVPLSRQALAILEQIKTFSGDHELIFIGDHNPRKPMSE
NTVNKSLRVMGYDTQIEVCGHGFRTMACSSLIESGLWSRDAVKRQMSHMERNSVRAAYIHKAEHLDERKLMLQWWADFLD
ANREKAVSPFDFAKINTSIKIQNGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 2e-161 84
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 1e-144 69
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 5e-145 69
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 5e-145 69
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 5e-145 69
int AAK00456.1 Int Not tested SHI-1 Protein 9e-135 69
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 8e-145 69
int AAK16198.1 Int Not tested PAI-I AL862 Protein 5e-144 69
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 5e-144 69
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 3e-143 68
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-144 68
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-143 68
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-143 68
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 8e-144 68
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 6e-144 68
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 8e-144 68
int AAL51028.1 CP4-like integrase Not tested LEE Protein 6e-144 68
int-phe AAL60261.1 Int-phe Not tested LEE Protein 6e-144 68
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 3e-142 68
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 4e-143 68
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-143 68
int CAC81896.1 integrase Not tested LEE II Protein 1e-133 67
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-127 61
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-127 61
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 6e-116 58
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 9e-83 57
int2 NP_993013.1 integrase Not tested HPI Protein 5e-111 56
int CAA21384.1 - Not tested HPI Protein 5e-111 56
int CAA08754.1 integrase Not tested HPI Protein 1e-111 56
int CAB59974.1 integrase Not tested HPI Protein 3e-112 56
int YP_002346908.1 integrase Not tested HPI Protein 5e-111 56
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 5e-111 56
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 9e-96 56
unnamed AAD17660.1 unknown Not tested HPI Protein 1e-107 54
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-111 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-111 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 5e-103 53
int AAD44730.1 Int Not tested SHI-2 Protein 2e-82 45
int CAC39282.1 integrase Not tested LPA Protein 5e-83 45
aec33 AAW51716.1 Int Not tested AGI-3 Protein 5e-83 45
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 5e-81 44
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 7e-81 44
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 7e-81 44
int AAC31482.1 CP4-like integrase Not tested LEE Protein 2e-81 43
int ACU09430.1 integrase Not tested LEE Protein 2e-81 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 3e-81 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 3e-81 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 1e-75 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 7e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intB YP_003529741.1 integrase VFG1536 Protein 1e-161 84
intB YP_003529741.1 integrase VFG0626 Protein 2e-145 69
intB YP_003529741.1 integrase VFG1693 Protein 6e-144 68
intB YP_003529741.1 integrase VFG0598 Protein 3e-81 44
intB YP_003529741.1 integrase VFG0783 Protein 1e-81 43