Gene Information

Name : metB (EAMY_0138)
Accession : YP_003529496.1
Strain : Erwinia amylovora CFBP1430
Genome accession: NC_013961
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 158533 - 159693 bp
Length : 1161 bp
Strand : +
Note : Cystathionine gamma-synthase (CGS) (O-succinylhomoserine (thiol)-lyase), PLP-dependent enzyme

DNA sequence :
ATGACGCGTAAACAGGCAACCATTGCAGTACGTAGCGGTTTGAATGATGACGAGCAGTATGGCTGCGTTGTCCCCCCTAT
TCACCTGTCCAGCACCTATAACTTCACCGAATTCAATCAGCCGCGCGTTCATGACTACTCTCGCCGGGGCAACCCGACAC
GTGATGTGGTGCAGCGTGCTCTGGCGGAGCTGGAGGGGGGATCCGGGGCGGTCATGACTAACACCGGGATGTCAGCGATT
CATCTGGTGTGCACGGTGTTTCTGCAGCCGGGCGACCTGCTGGTCGCGCCGCACGACTGTTACGGTGGCAGCTACCGCCT
TTTTGATAGCCTGAGTAAGCGCGGTGCTTATCGCGTGGAATTTGTCGACCAGGGCGACGAAGCTGCGTTACAGGCCGCGC
TGGCGCAGAAACCGAAGCTGGTCCTGATTGAAAGCCCGAGCAACCCGCTGCTGCGCGTGGTTGATATTGCCAGCATCTGT
CAGGCGGCGGCGGCGGCTGGCGCGATCAGCGTTGTGGATAACACCTTCCTTAGCCCGGCATTGCAAAACCCGCTGGCGCT
GGGTGCTGACCTGGTTATTCACTCCTGCACGAAATATCTCAACGGTCACTCCGATGTGGTGGCCGGGGCGGTGATTGCCA
AAGACCCGCAGCATGTTACCGAGCTTGCCTGGTGGGCTAACAATATCGGCGTAACCGGTGCGGCGTTTGACAGCTACCTG
CTGCTGCGTGGGCTGCGCACACTGTCTCCGCGTATGGCCGCAGCACAACGTAATGCACTGGCGATTGTCGATTACCTGAA
GCAACAACCGCTGGTGAAAAAGTTGTATCATCCTTCGCTGCCGGAGAACGCCGGGCATCAGTTTGCACTTACTCAACAAA
AAGGCTTTGGCGCAATGCTGAGTTTTGAGCTGGATGGTGACGAGGCAACGCTGCGCCGTTTTCTCAAAGCGCTGCAATTA
TTCACTCTGGCGGAATCGCTGGGCGGCGTGGAAAGCCTGATTTCCCATACCGCCACCATGACGCATGCCGGCATGTCGGC
CGCAGCACGCGCCGCGGCGGGCATTGCCGAAACGTTACTGCGGATTTCGGTGGGAATTGAAGATCATGAAGATTTAATCG
CCGATCTGGATAATGCGTTTCAGGTTGCGGCCAAGAGGTGA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTEFNQPRVHDYSRRGNPTRDVVQRALAELEGGSGAVMTNTGMSAI
HLVCTVFLQPGDLLVAPHDCYGGSYRLFDSLSKRGAYRVEFVDQGDEAALQAALAQKPKLVLIESPSNPLLRVVDIASIC
QAAAAAGAISVVDNTFLSPALQNPLALGADLVIHSCTKYLNGHSDVVAGAVIAKDPQHVTELAWWANNIGVTGAAFDSYL
LLRGLRTLSPRMAAAQRNALAIVDYLKQQPLVKKLYHPSLPENAGHQFALTQQKGFGAMLSFELDGDEATLRRFLKALQL
FTLAESLGGVESLISHTATMTHAGMSAAARAAAGIAETLLRISVGIEDHEDLIADLDNAFQVAAKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-55 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-56 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-43 41