Gene Information

Name : Nhal_0897 (Nhal_0897)
Accession : YP_003526459.1
Strain : Nitrosococcus halophilus Nc 4
Genome accession: NC_013960
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 909322 - 910881 bp
Length : 1560 bp
Strand : -
Note : PFAM: N-6 DNA methylase; KEGG: sat:SYN_00494 type I restriction-modification system methylation subunit

DNA sequence :
ATGGCCAAGACCGCCGACAAAACCCCGAAAAAAACTGAGGAACCCCTGCAAAAGAGCCTCTGGAAGAGCGCCGACAGGCT
GCGCAAGAACATGGACGCCGCCGAGTACAAGCACGTCGTCCTCGGCCTGATCTTCCTCAAGTACATCTCCGATGCCTTCG
AAGAGCTGCACGCCAAATTATCCGAAGGGTTGGGCGAATACGCCGGGGCCGACCCGGAGGATGCCGACGAGTACCGTGCC
GAAAACGTCTTCTTTGTCCCCGAGGGCGCTCGCTGGTCCTATCTCCAGGCTCGCGCCAAACTGCCTGGGATCGGCAAGGA
TGTGGACGAGGCCATGGAAGCCATCGAGAAGGAGAACCCTACCCTGAAAGGCGTGCTGCCCAAGCAGTACGCCCGCCAGA
ACCTGGACAAGGCCAGCCTGGGAGCGCTGATCGATCTGCTCGGCAAGATCGGCCTGGGCGACGCCACCGCCCGCAGCCGG
GACATCCTCGGCCGGGTCTATGAATATTTTCTCGGCGAATTCGCCGCCGCCGAGGGCAAGAAGGGCGGCCAGTTCTACAC
CCCGGCGGCCATCGTCAAGCTGCTGGTCAACATGCTGGAGCCCTACAAAGGAAGGGTCTACGACCCCTGCTGCGGCTCCG
GCGGCATGTTCGTCCAGTCCGAGAAGTTCGTCGAGGTCCACCAGGGGCGCATCGACGACATCTCCATCTACGGCCAGGAA
TCCAACCAAACCACCTACCGCCTCTGCCGTATGAACCTGGCCATTCGCGGTATCGACGGCTCCAATGTGCGCTGGAACGG
CGAAGGCAGCTTCCTCAACGACGCCCATAAGGACATGAAGGCCGAGTACATCATCGCCAACCCACCTTTCAACGACTCCG
ATTGGTCCGGCGAGCTGCTGCGCGACGACCCCCGCTGGCAGTTCGGCGTGCCCCCCGTGGGCAACGCCAACTTTGCCTGG
ATGCAGCACATGATCTACCACCTTGCCCCCAACGGCACCCTGGGGCTGGTGCTCGCCAACGGCTCGCTCTCCTCCAACAG
CGGCGGCGAGGGGGAGATCCGCAAGGCCATTATCGAGGCCAAGCTGGTGGACTGCATCGTCGCCCTGCCGGACAAGCTCT
TTTACAACACGGGCATTCCCGCCTGCCTCTGGTTCATCTCCCACGACCGGCGCAACCACAATTTCCGCAACCGCGAGGAC
GAAATCCTTTTCATCGATGCTCGCAACCTGGGCCAGATGATTACCCGGCGTAACCGGGACTTCTCCGATGAAGACATCGC
CCGCATCGCCGACACCTACCACGCTTGGCGTAACAAGGACGGCGGTTATGAGGACGTTAAGGGCTTCTGCAAGGCTGCGA
CCTTGGAGGACGTTCGCAAGCACAAGCACGTGCTGACGCCGGGGCGCTATGTAGGCATACCCGACGAGGAGGACGACGGC
GTGCCGTTTGAGGAGAAGATGACTAAGCTCACCGAAGAACTGGCCGCGCAGATGGCGCAGGGCCAGGCGCTGGATGCTCG
GATTCGGGAAAATCTGGCGAAGGTGGGGTTTGGGGTATGA

Protein sequence :
MAKTADKTPKKTEEPLQKSLWKSADRLRKNMDAAEYKHVVLGLIFLKYISDAFEELHAKLSEGLGEYAGADPEDADEYRA
ENVFFVPEGARWSYLQARAKLPGIGKDVDEAMEAIEKENPTLKGVLPKQYARQNLDKASLGALIDLLGKIGLGDATARSR
DILGRVYEYFLGEFAAAEGKKGGQFYTPAAIVKLLVNMLEPYKGRVYDPCCGSGGMFVQSEKFVEVHQGRIDDISIYGQE
SNQTTYRLCRMNLAIRGIDGSNVRWNGEGSFLNDAHKDMKAEYIIANPPFNDSDWSGELLRDDPRWQFGVPPVGNANFAW
MQHMIYHLAPNGTLGLVLANGSLSSNSGGEGEIRKAIIEAKLVDCIVALPDKLFYNTGIPACLWFISHDRRNHNFRNRED
EILFIDARNLGQMITRRNRDFSDEDIARIADTYHAWRNKDGGYEDVKGFCKAATLEDVRKHKHVLTPGRYVGIPDEEDDG
VPFEEKMTKLTEELAAQMAQGQALDARIRENLAKVGFGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 6e-137 60
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 5e-138 60
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 8e-137 59
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-107 48