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Name : Nhal_0892 (Nhal_0892) Accession : YP_003526454.1 Strain : Nitrosococcus halophilus Nc 4 Genome accession: NC_013960 Putative virulence/resistance : Unknown Product : type I site-specific deoxyribonuclease, HsdR family Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : 3.1.21.3 Position : 902096 - 905299 bp Length : 3204 bp Strand : - Note : KEGG: sat:SYN_00497 type I restriction-modification system restriction subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase DNA sequence : GTGTCGGACAAGTTGACGGAATCGGCCATTGAGAACCTGGCTATTGAGCTGCTGGCCAATCAGGGCTACCAATACCTCCA CGGTGCCGATCTGGCCCCTGATGCGCCCAACCCTGGGCGCCCCTCGTTCGGCGATGAGTTCCTAGTGGGCCGGTTGCAGG ATGCGGTCGCACGGCTAAATCCGACGATCCCGCCGGACGCTCAGGAGCAGGCAATCAAGGAAATCTTGCGCTTGGCCGTG GAGACCGGCTCGACTAGGGAGCTGTTGGCGGCTAATGAAGCTTTTCATAGGCTCCTGACCAATGGCGTGGAGGTGGAGTT TCAGCACGAAGGGCGGACCAAGGGCGACAAGGTCTGGCTAGTGGACTTCGCCAATCCGGCGGCGAACGATTGCCTGGTAG TGAATCAGTTCACCGTCACCACCAAGTCCGGCCACGGGCACGTCAACAAGCGGCCCGACCTGGTGCTGTTCATCAACGGC CTGCCCCTGGTGGTGGTCGAGTTGAAAAATGCCGCCAGCGAGAATGCCACCGTACGTTCTGCCTATGAACAACTCCAGAC CTACAAGCATGCTATCCCCAGTCTGTTCTTGGCCAATGGGCTGTTGGTCGCTTCCGACGGGCTGGAGGCGCGCATGGGGT CACTTTCCGCTGGCTTCAGCCGCTTCATGGCCTGGAAGACGACGGATGGAAAGAAGGAGGCGTCGCACCGGGTCGGGCAG TTGGAGACTCTGATTCAGGATGTATTGAAGCCCGCCACCTTACTGGAGTTGATCCGCCACTTTACGGTGTTCGAGAAGTC CCGTCGGGAAGACCCCAAGACGGGGCTGACAACGGTGGAGACGGTGAAGAAGACTGCCGCTTATCACCAGTTCTACGCGG TGAAGAAGGCGGTGGAATCGACCCTGCACGCTACCGGTACGGACGGCAGCCGCAAGGGCGGGGTGGTGTGGCATACGCAG GGCAGCGGCAAGTCGCTCTCCATGGTCTTCTATGCGGGCAAGCTGGTGCTGGCATTGGACAACCCGACCATCGTGGTGCT GACTGATCGCAACGATCTGGACGACCAGCTCTTCGATACCTTCGCCGCCAGTCGCCAATTACTGCGTCAGGAGCCAGTGC AGGCAGAAAATCGGGACGACCTGCGCGACAAGCTCAAGGTGGCCTCGGGGGGAGTTATCTTCACCACCATGCAGAAGTTC TCGCCGAAGAATGGCGAGGCGATCTATCCGCTACTTTCCGACCGCCGCAATATCGTGGTGATCGCCGACGAGGCCCACCG CAGCCAGTATGGGTTCAAGGCCAAGGAGGTGGACATCAAGGATGCGGATGACAACATCGTCGGCAAGAAGACCGCTTACG GCTTCGCCAAGTATCTGCGCGACGCATTGCCCAATGCCACCTTTATTGGTTTTACCGGCACCCCGGTGGAACTGGACGAC AAGAATACTCCGGCCGTTTTCGGCGATTATGTGGACGTCTATGACATCGCTCAGGCAGTGGAGGATGGCGCGACAGTACG CATCTACTATGAGAGCCGATTGGCCAAAGTACGGTTAAAGGAAAAAGAGAAAGAGGCTCTGGATCAGCGTTTCGACCAGG TCATGGAAGATGCTGCAGATTATGAAACGGGGTTCAGCGATGAGGACGAGTTGAGCGAGAAAGCCAAGGCTAAATGGACA CAGCTAGAGGCCATTGTGGGCAATCGGCAACGGGTGGAGAACGTGGCCCGCGATCTGGTGGCGCACTTTGAAGAGCGGCA GAAGATATTCGACGGCAAAGGACTAATCATCGCCATGAGCAGGCGCATCTGCGTCGAACTCTACGACGCCATCGTTACGC TACGCCTTGGGTGGCATAGCGACGACGATGCCCAGGGTGCCATCAAGGTGATCATGACCGGTTCCAGTGCCGACCCGCAG GCGATGCAGCCGCACATCCGCAGCAAGGAGGCGCGGAAGGCGATTGGGGAGCGTTTGAAGGACCCGGGCGATCCGCTGAA GCTGGTTATTGTGCGGGATATGTGGCTGACCGGCTTCGATGCGCCCTGCCTGCATACCCTCTACGTGGACAAGCCGATGA AGGGACACAACCTGATGCAGGCCATCGCGCGCGTGAACCGGGTCTATAAGGACAAGCCGGGGGGGCTGGTGGTGGACTAC ATCGGGATCGCCTCCGACCTGAAGCGGGTGCTAGCGATCTATACCGAGAGCGGCGGCAAGGGCCAGCCTACGCTGGATAT TGATGATGCCGTCCGCGCCATGCAGGAAAAATTCGAGGTCGTCCAACAGATGCTGGCGGGATTTGACTACCGCCGCTACT TCGGGGCAAACACCTCAGGCAAGCTGACGATCATCCTGGAGGCAGAGGAGTACGTTCTTGCTCTAGAGGACGGCAAGGCG CGTTTCTCGAAGGAGGTCGACTTGCTGGCGAAGGCGTTTGCGCTCTCCGTGCCGGATGAACGGGCCATGGCCATCAAAGA CGAGCTCGCCTTTTTCCAGGCGGTGAAGGCGCGGCTGGCCAAGTTTGAGCGCGGCGAAGGCAAGAGCAAGGAAGAGCTGG ATTCGGCTATTCGGCAGTTGGTAGACGAGGCGGTCGTCTCCGATCAGGTGGTGGACATCTTCGATGCGGCGGGGATCAAA AAGCCGGATATTTCCATTCTCTCCGATGAGTTCATGGCGGAAATCAAAGGGATGCAGCATCGGAATCTGGCGCTGGAACT GCTGAGGAAAATTCTCAACGATGAGATTCGCGTTCGCTCCAAAAAGAATCTGGTGCAGAGCAGGGCATTGTCCGAAATGC TGGAGAGTGCCATCAAGCGCTATCAGAACAACCTGCTGTCGGCCGCCGGGATCATCGAAGAGCTGATCGAACTGGCCAGG GAGATCAAGGAGGCGGATCGACGAGGCGAAAAACTGGGGCTAACGGAGGATGAGCTGGCCTTCTATGACGCCCTTGAAGT GAATGACAGCGCAGTACAGGTGCTTGGCGATAACCAGTTGCGCGAGATCGCACGGAAGTTGGTGGAGAAAGTAAAGCAGA ACGCTACCATCGACTGGACGGTAAAGGAGAGCGTACGCTCCAAGTTGAAGGTGATCGTCAAGCGGATTCTACGCAAGTAT GGCTACCCGCCAGACAAGCAGGCGACCGCAACCGAGACAATTCTGAAGCAGGCGGAGTTGTTGGCCGAGAGCTGGGCTGT ATAA Protein sequence : MSDKLTESAIENLAIELLANQGYQYLHGADLAPDAPNPGRPSFGDEFLVGRLQDAVARLNPTIPPDAQEQAIKEILRLAV ETGSTRELLAANEAFHRLLTNGVEVEFQHEGRTKGDKVWLVDFANPAANDCLVVNQFTVTTKSGHGHVNKRPDLVLFING LPLVVVELKNAASENATVRSAYEQLQTYKHAIPSLFLANGLLVASDGLEARMGSLSAGFSRFMAWKTTDGKKEASHRVGQ LETLIQDVLKPATLLELIRHFTVFEKSRREDPKTGLTTVETVKKTAAYHQFYAVKKAVESTLHATGTDGSRKGGVVWHTQ GSGKSLSMVFYAGKLVLALDNPTIVVLTDRNDLDDQLFDTFAASRQLLRQEPVQAENRDDLRDKLKVASGGVIFTTMQKF SPKNGEAIYPLLSDRRNIVVIADEAHRSQYGFKAKEVDIKDADDNIVGKKTAYGFAKYLRDALPNATFIGFTGTPVELDD KNTPAVFGDYVDVYDIAQAVEDGATVRIYYESRLAKVRLKEKEKEALDQRFDQVMEDAADYETGFSDEDELSEKAKAKWT QLEAIVGNRQRVENVARDLVAHFEERQKIFDGKGLIIAMSRRICVELYDAIVTLRLGWHSDDDAQGAIKVIMTGSSADPQ AMQPHIRSKEARKAIGERLKDPGDPLKLVIVRDMWLTGFDAPCLHTLYVDKPMKGHNLMQAIARVNRVYKDKPGGLVVDY IGIASDLKRVLAIYTESGGKGQPTLDIDDAVRAMQEKFEVVQQMLAGFDYRRYFGANTSGKLTIILEAEEYVLALEDGKA RFSKEVDLLAKAFALSVPDERAMAIKDELAFFQAVKARLAKFERGEGKSKEELDSAIRQLVDEAVVSDQVVDIFDAAGIK KPDISILSDEFMAEIKGMQHRNLALELLRKILNDEIRVRSKKNLVQSRALSEMLESAIKRYQNNLLSAAGIIEELIELAR EIKEADRRGEKLGLTEDELAFYDALEVNDSAVQVLGDNQLREIARKLVEKVKQNATIDWTVKESVRSKLKVIVKRILRKY GYPPDKQATATETILKQAELLAESWAV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 48 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 48 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 48 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 47 |
