Gene Information

Name : Nhal_2318 (Nhal_2318)
Accession : YP_003527793.1
Strain : Nitrosococcus halophilus Nc 4
Genome accession: NC_013960
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2389624 - 2392221 bp
Length : 2598 bp
Strand : +
Note : KEGG: noc:Noc_2381 ATP-dependent Clp protease; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA

DNA sequence :
ATGCGACAGGACAAGTTAACCACCAAGTTTCAGGAGGCCCTGGCTGATGCCCAAAGCCTGGCTGTGGGGCAGGACCATCA
ATTTCTGGAACCGCTGCATGTAATGTTTGCCCTGCTAGAACAGCAAGGCGGGACCGCAGCCCCCTTATTGATGCAGGCAG
GAGTGAATGTCAACAATTTCCATGCCCAGCTCAGCGAGGCTCTGAAACGGCTTCCCCAAGTACAGGGCGTTCCGGGAGAG
ATACATATCTCTCAAGATTTGATGCGGTTGCTCAATGTGACCGATAAGCTGGCCCAGCAGCGCCATGATCAATATATCTC
CAGTGAATTATTCATGCTTGCCGCTGTGGAGGATAGGGGCCAGGTGGGCGAGTTGTTGCGTAAAAATGGCGCCACTAAGG
CGAGTATAGAGGCGGCTATCAATACCATCCGTGGGGGGCGACAAGTGAATGAACCGGGGGCCGAGGACCAACGCCAGGCC
CTAGAGCGCTATACCATCGATCTCACGGAGCGGGCCGAGCAGGGTAAATTAGATCCGGTCATTGGCCGTGATGATGAGAT
ACGCCGCACTATTCAGGTGCTGCAACGCCGGACTAAAAATAATCCCGTGCTGATTGGTGAACCGGGGGTGGGTAAAACTG
CCATTGTCGAGGGATTAGCCCAGCGTATTGTCAACAGCGAGGTCCCAGAAGGACTCAAGCATAGGCGTTTGCTTGCGCTG
GATATGGGGGCCCTGATTGCCGGTGCCAAGTTCCGGGGCGAGTTTGAGGAGCGCCTTAAGGCGGTGCTCAAGGACATCAG
CAAGGCAGAAGGGAATATTATTTTATTTATTGACGAACTCCATACAGTGGTGGGGGCGGGTAAGGCGGAAGGAGCCATGG
ATGCCAGTAACATGCTCAAACCGGCCTTGGCTCGCGGTGAACTTCACTGCATTGGGGCAACGACCCTGGATGAGTATCGT
CAATACATAGAAAAAGACGCGGCTTTGGAACGGCGTTTCCAAAAGGTGCTGGTGGATGAGCCAAGCTTAGAAGATACCAT
TGCTATCCTGCGGGGCTTGAATGAGCGCTATGAAGTCCATCATGGGGTGGAGATCACCGATCCTGCCATTGTGGCGGCAG
CCACTTTATCCCACCGTTATATTACCGATCGCAAACTTCCAGACAAGGCCATTGATCTCATCGACGAGGCTGCCAGCCGC
ATTCGGATGGAGATCGATTCCAAGCCGGAGCCCATGGACCGGATGGAAAGACGCTTGGTTCAATTGAAAATTGAGCGGGA
AGCTTTACGGAAGGAAACTGACGAAGCCTCTAAAAAGCGTCTGGAGACTTTGGAAACCGAGATTAACCATTTGGAAAAAG
AATATGCCGATCTAGAAGAGATTTGGAAGGCGGAGAAAGCCGCCCTAAGCGGTGCCCAGGGGATCAAGGAAAAACTGGAA
CAGGCTCGATTGGAGCTGGACTCCGCCCGCCGTGCCGGAGATTTAACTCGGATGTCGGAGTTACAGTATGGCCAGATCCC
GGAACTCCAAAAACAGCTCGATGCGGCCACCGCGGCTGAACAGCAGGATTTTAAATTACTGCGCAACAAGGTGACTGAGG
AAGAAATTGCCGAGGTGGTTTCCAAATGGACGGGAATTCCGGTTTCCAAAATGCTGGAAGGAGAGCGGGAGAAATTATTA
AAAATGGAAGAGGCGTTGCATCGGCGAGTGGTGGGCCAGGAAGAAGCCATCGAAGTGGTAAGTAACGCGATTCGCCGTTC
CCGGGCCGGGCTAGCTGATCCTAACCGGCCGAATGGTTCCTTCCTCTTTCTCGGGCCTACGGGGGTAGGAAAGACTGAGC
TTTGTAAGGCCCTGGCGGCTTTCTTGTTTGATACGGAGGAAGCCATGGTTCGCATCGACATGTCCGAGTTTATGGAGAGG
CACTCCGTGGCCCGGCTCATCGGGGCTCCTCCCGGTTATGTGGGGTTTGAAGAGGGGGGCTACCTCACCGAGGCGGTACG
CCGCAAGCCCTATTCGGTCATCTTGCTCGACGAGGTGGAGAAGGCCCACCCGGATGTATTTAATATTTTGCTCCAAGTTT
TGGATGATGGACGGCTGACAGATGGCCACGGTCGCACGGTAGATTTTCGCAATACAGTGGTGGTCATGACTTCTAACCTC
GGTTCCCATGTGATTCAGGAAATGGCCGGGGAGGAACATTACCAGGAAATGAAAAATGCGGTAATGGAGATTGTCGGGCA
GCATTTCCGTCCGGAATTTATTAACCGAGTGGACGATGTGGTGGTGTTCCATCCCCTGTTGAAAGGGCAGATCCGGGCGA
TTGCCAAACTTCAGATTGGCCATCTCCAGCAGCGACTGCGAGAGCGGGATATGGATTTAGCCGTGTCCGAAACTGCTCTG
GATAAATTGGCAGAAGTGGGTTTCGATCCGGTTTATGGAGCTAGGCCCCTCAAGCGGGCGATTCAGCAACAAATCGAGAA
CCCCCTAGCCCAGGAAATCCTAGGGGGAAAATTTGAGCCTGGGGATCTGATTGAAGTGGGAGTTGAAGGCGAACATTTCG
TTTTCGAGCGCAAAGCAAGGGCAGCTTCTGCCGCCTAG

Protein sequence :
MRQDKLTTKFQEALADAQSLAVGQDHQFLEPLHVMFALLEQQGGTAAPLLMQAGVNVNNFHAQLSEALKRLPQVQGVPGE
IHISQDLMRLLNVTDKLAQQRHDQYISSELFMLAAVEDRGQVGELLRKNGATKASIEAAINTIRGGRQVNEPGAEDQRQA
LERYTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNSEVPEGLKHRRLLAL
DMGALIAGAKFRGEFEERLKAVLKDISKAEGNIILFIDELHTVVGAGKAEGAMDASNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVDEPSLEDTIAILRGLNERYEVHHGVEITDPAIVAAATLSHRYITDRKLPDKAIDLIDEAASR
IRMEIDSKPEPMDRMERRLVQLKIEREALRKETDEASKKRLETLETEINHLEKEYADLEEIWKAEKAALSGAQGIKEKLE
QARLELDSARRAGDLTRMSELQYGQIPELQKQLDAATAAEQQDFKLLRNKVTEEEIAEVVSKWTGIPVSKMLEGEREKLL
KMEEALHRRVVGQEEAIEVVSNAIRRSRAGLADPNRPNGSFLFLGPTGVGKTELCKALAAFLFDTEEAMVRIDMSEFMER
HSVARLIGAPPGYVGFEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGHGRTVDFRNTVVVMTSNL
GSHVIQEMAGEEHYQEMKNAVMEIVGQHFRPEFINRVDDVVVFHPLLKGQIRAIAKLQIGHLQQRLRERDMDLAVSETAL
DKLAEVGFDPVYGARPLKRAIQQQIENPLAQEILGGKFEPGDLIEVGVEGEHFVFERKARAASAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-174 44
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-108 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-106 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-106 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nhal_2318 YP_003527793.1 ATP-dependent chaperone ClpB VFG2076 Protein 4e-121 44