Gene Information

Name : Nhal_1676 (Nhal_1676)
Accession : YP_003527191.1
Strain : Nitrosococcus halophilus Nc 4
Genome accession: NC_013960
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1706607 - 1708100 bp
Length : 1494 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: shn:Shewana3_4345 mercuric reductase

DNA sequence : 
ATGACCGATACGCCGGGAGCGAATCGGGACCTCCGAAGGAGGCCCCCAGGGGGCGCGCCAGGGCAGGCGCGCATCAATAA
TTGCTGCGAGAAAAAGGAAGGCAATGATATCGCGGTGGTGGGTAGCGGTGGGGCGGCCATGGCTGGGACACTCAAGGCCG
TCGAACGGGGGGCGCGGGTCACACTGATCGAGCGCGGCGTCATGGGCGGCACCTGCGTCAATGTGGGCTGCGTGCCGTCC
AAGATCATGATTCGCGCGGCTCACATCGCCCAGCTACGCCGGCAAAGCCCGTTTGACGACGGTATCCCGGCAGCACCGCC
GGCGATCCTGCGCGAACGGCTGCTGGCCCAGCAGCAGGGGCGCGTAGAGGAATTGCGGCAGGCCAAGTACGAAAGCATTT
TAGATGACAACCCGGCCATTACCGTGCTGCACGGCGAAGCTCGATTCAAGAATGATCGTCGTCTCACTGTGCGTCTAAAT
GACGGCGGCGAGCGCGAGGTGACCTTCGACCGCTGCCTGATCGCCACTGGGGCGAGCCCCACCATCCCGCCCATTCCCGG
CCTGAAAGACACGCCCTACTGGACCTCTACCGAGGCCCTCGCAAGCGACAGAATACCGGAGCGCCTAACCGTGATCGGCT
CCTCGGTGGTCGCCGCGGAGCTGGCCCAAGCCTTCGCCCGGCTGGGCAGCCGAGTGACGATCCTGGCGCGCAGCACCTTA
TTTTTCCGCGAAGACCCGGCCATCGGGGAAGCGCTCACGGCGGCTCTCCGTGCCGAAGGCATCGAAGTGCTGGAGCACAC
CCAGGCCAGTCAGGTGACCCAAGGGGACGGAGAACTCCTGCTCACCACCAGGCACGGCTCGCTGGGCGCCGACAAACTGT
TGGTCGCCACTGGCCGGGCGCCCAATACGGGCGACTTGGGACTGGAAACCGCGGGTGTGGCCGTCAATGGGCAGGGCGCC
ATCGTCGTTGACGCCGGGATGCGCACCAGCAACCCACATATCTACGCTGCCGGTGACTGCACCGACCAGCCGCAATTCGT
CTATGTGGCGGCGGCGGCCGGCACCCGCGCGGCGGTTAACATGACCGGCGGTGAAGCCGCCCTCGATCTGACCGCCATGC
CGGCGGTGGTGTTCACCGATCCGCAGGTCGCCACCGTAGGCTACAGCGAAGCGGAAGCACACCACGATGGCATTGAGACC
GACAGCCGCCTGCTTACGCTAGACAACGTGCCGCGGGCGCTCGTTAACTTCGATACCCGTGGCTTCATCAAGCTGGTCAT
CGAGGAAGGCAGCCGGCGGCTGATTGGCGTGCAGGCCGTGACTCCAGAAGCAGGCGAACTCATCCAGGCAGCGGCACTGG
CCATCCGGACGCGGATGACTGTGGAGGAACTGGCCGACCAGTTGTTTCCCTACCTGACCATGGTCGAGGGGTTGAAGCTT
GCGGCGCAAACTTTCACCAAGGACGTGAAGCAACTGTCCTGCTGCGCCGGGTGA

Protein sequence : 
MTDTPGANRDLRRRPPGGAPGQARINNCCEKKEGNDIAVVGSGGAAMAGTLKAVERGARVTLIERGVMGGTCVNVGCVPS
KIMIRAAHIAQLRRQSPFDDGIPAAPPAILRERLLAQQQGRVEELRQAKYESILDDNPAITVLHGEARFKNDRRLTVRLN
DGGEREVTFDRCLIATGASPTIPPIPGLKDTPYWTSTEALASDRIPERLTVIGSSVVAAELAQAFARLGSRVTILARSTL
FFREDPAIGEALTAALRAEGIEVLEHTQASQVTQGDGELLLTTRHGSLGADKLLVATGRAPNTGDLGLETAGVAVNGQGA
IVVDAGMRTSNPHIYAAGDCTDQPQFVYVAAAAGTRAAVNMTGGEAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIET
DSRLLTLDNVPRALVNFDTRGFIKLVIEEGSRRLIGVQAVTPEAGELIQAAALAIRTRMTVEELADQLFPYLTMVEGLKL
AAQTFTKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 86
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 86
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 85
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 85
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 85
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-173 84
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-175 83
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-175 83
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-175 83
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-169 79
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-84 44
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-84 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nhal_1676 YP_003527191.1 mercuric reductase BAC0652 Protein 2e-178 84
Nhal_1676 YP_003527191.1 mercuric reductase BAC0653 Protein 2e-172 78
Nhal_1676 YP_003527191.1 mercuric reductase BAC0650 Protein 1e-155 73
Nhal_1676 YP_003527191.1 mercuric reductase BAC0651 Protein 2e-84 44
Nhal_1676 YP_003527191.1 mercuric reductase BAC0224 Protein 2e-82 44