Gene Information

Name : ureB (HMU03060)
Accession : YP_003516311.1
Strain : Helicobacter mustelae 12198
Genome accession: NC_013949
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 365521 - 367230 bp
Length : 1710 bp
Strand : +
Note : evidence=ISS; db_xref=pmirabilis:PMI3685; date=20070321; method=automatic:reciprocal fasta

DNA sequence :
ATGATTAAGATTTCAAGAAAAGAATATGTTTCAATGTATGGACCAACCACAGGAGATAAAGTAAGACTTGGAGACACAGA
ACTCATCGCAGAAATCGAAAAAGACTATACAGTTTATGGAGAAGAGATCAAGTTTGGTGGTGGTAAGACCATCCGCGATG
GTATGTCACAATCTGTGAGTCCCGATGTAAATGAACTCGATGCAGTGATCACAAATGCAATGATCATTGACTATACAGGA
ATTTACAAAGCAGACATCGGCATCAAAGATGGCAAGATCGCAGGAATTGGCAAAGCAGGAAACAGAGATACGCAAGATGG
TGTGGGCATGGATTTGGTCGTAGGTGCTAGCACAGAAGCAATCGCGGGTGAAGGTTTGATTGTCACAGCTGGTGGAATTG
ACACTCATATTCACTTTATTTCTCCTACACAAATTCCCACAGCACTTTATAGTGGTGTCACTACAATGATTGGTGGTGGT
ACAGGTCCTGCGGCAGGTACTTTTGCAACTACGATTTCTCCTGGTGAGTGGAATATCAAACAAATGATTCGCGCTGCTGA
GGAATACACCATGAATCTTGGATTTTTTGGTAAGGGCAATACATCTAATGTAAAAGCGCTTGAGGATCAAATCAAAGCAG
GTGCGCTAGGATTTAAGGTACATGAGGACTGGGGCTCCACTCCTGCTGTAATCAATCATTCTCTCAATATTGCAGAGAAA
TATGATGTACAAGTTGCCATCCACACAGATACGCTCAATGAGGGAGGTGCTGTGGAAGATACGTTAGCAGCAATCGGTGG
TAGAACTATCCACACTTTCCATACAGAAGGCGCAGGCGGTGGACATGCTCCAGATATTATTAAGGCAGCAGGAGAGGCGA
ATATTTTGCCAGCTTCTACCAATCCTACAATTCCTTTCACAAAGAATACAAAAGATGAGCACTTGGATATGTTGATGGTT
TGCCACCATTTGGACAAAAACATCAAAGAAGACGTTGCGTTTGCAGATAGCCGTATCCGCCCTGAAACCATCGCAGCAGA
AGATGCTTTGCATGATATGGGGATTTTCTCTATCACTAGCTCTGACTCTCAGGCGATGGGACGCGTAGGAGAGGTAATTA
CTAGAACTTGGCAGGTGGCAGATAAATCCAAAAAAGAATTTGGTCGCTTGAAAGAAGAGACTGGTGATAATGACAATTTT
AGAATCAAGCGCTATGTTTCTAAGTACACCATTAATCCAGCCATTGCGCATGGAATCTCTGATTATATCGGATCTGTAGA
AAAGGGTAAAATCGCAGATTTGGTTTTGTGGGATCCAGGTCTTTTTGGAATCAAGCCTGAGACAATCATCAAAGGCGGTA
TGATTGTTGCATCCAAAATGGGAGATTCCAATGCTTCTATCCCAACTCCAGAGCCTGTAGTGTACAAAGATATGTTTGGC
GCGCATGGAAAGGCAAAGTATAAGTGCAATGTGACTTTTGTCTCTCAGGCTTCCCTAGATCTTGGAATCAAAGAAGAATT
GGGGCTTGAGCGAACATTGCTGCCAGTGAAGAATTGCAGAAACATTGGGAAAAGAGATATGAAGTTTAATGATGTTGTCG
CACATATTGACGTGAATCCAGAGACCTACAAAGTTAAAGTAAATGGCAAAGAGGTTACATCTAAGTCTGCAGATAGTGTA
CCACTAAGTCAGCTTTATAATTTGTTTTAA

Protein sequence :
MIKISRKEYVSMYGPTTGDKVRLGDTELIAEIEKDYTVYGEEIKFGGGKTIRDGMSQSVSPDVNELDAVITNAMIIDYTG
IYKADIGIKDGKIAGIGKAGNRDTQDGVGMDLVVGASTEAIAGEGLIVTAGGIDTHIHFISPTQIPTALYSGVTTMIGGG
TGPAAGTFATTISPGEWNIKQMIRAAEEYTMNLGFFGKGNTSNVKALEDQIKAGALGFKVHEDWGSTPAVINHSLNIAEK
YDVQVAIHTDTLNEGGAVEDTLAAIGGRTIHTFHTEGAGGGHAPDIIKAAGEANILPASTNPTIPFTKNTKDEHLDMLMV
CHHLDKNIKEDVAFADSRIRPETIAAEDALHDMGIFSITSSDSQAMGRVGEVITRTWQVADKSKKEFGRLKEETGDNDNF
RIKRYVSKYTINPAIAHGISDYIGSVEKGKIADLVLWDPGLFGIKPETIIKGGMIVASKMGDSNASIPTPEPVVYKDMFG
AHGKAKYKCNVTFVSQASLDLGIKEELGLERTLLPVKNCRNIGKRDMKFNDVVAHIDVNPETYKVKVNGKEVTSKSADSV
PLSQLYNLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-155 63
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-155 63
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-147 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-147 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-147 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-147 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_003516311.1 urease subunit alpha VFG0270 Protein 0.0 79