Gene Information

Name : ureB2 (HMU13010)
Accession : YP_003517278.1
Strain : Helicobacter mustelae 12198
Genome accession: NC_013949
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1413229 - 1414935 bp
Length : 1707 bp
Strand : -
Note : evidence=ISS; db_xref=bcenocepacia:CAL3106; date=20070321; method=automatic:reciprocal fasta; Duplicated gene in HMU03060

DNA sequence :
ATGAAAATGAAAAGACAAGAATATGTTAATACTTATGGCCCCACAACTGGCGATAAAGTACGCCTTGGTGATACGGACCT
TTGGGCAGAGGTGGAGCATGATTACACCGTCTATGGTGAAGAGCTCAAATTTGGTGCGGGTAAAACCATCCGCGAGGGTA
TGGGACAAAGTAATAGCCCAGATGAAAACACACTAGATTTGGTCATCACCAATGCCCTTATCATCGATTACACTGGGATT
TACAAAGCAGATATTGGAATCAAAAATGGCAAGATCCATGGCATTGGAAAAGCGGGCAACAAGGATATGCAAGATGGCGT
CACTCCTCATATGGTCGTTGGTGTAGGCACAGAAGCGCTTGCAGGAGAGGGTATGATCATCACTGCTGGTGGGATTGATA
GCCATACACACTTCCTCTCTCCTCAACAATTCCCCACAGCCCTAGCCAATGGCGTTACAACCATGTTTGGTGGCGGTACA
GGCCCTGTGGATGGTACAAATGCGACTACGATCACCCCAGGTGTGTGGAATTTGCATCGCATGCTGCGTGCTGCTGAAGA
GTATGGGATGAATGTGGGCCTTCTGGGCAAAGGAAACAGCTCTAGCCGCGCTCAATTGGTAGAGCAAGTAAAAGCGGGTG
CGATTGGATTTAAATTGCATGAAGACTGGGGTACAACACCAAGTGCAATCGATCACTGCCTTAGTGTAGCTGATGAGTAT
GATGTACAAGTTTGCATCCACACTGATACTGTAAATGAAGCAGGTTATGTAGATGACACACTCAGAGCGATGAATGGACG
CGCGATCCATGCTTATCACATTGAGGGTGCAGGAGGAGGACACTCTCCTGATGTTATCACCATGGCTGGTGAAGTGAACA
TTCTCCCTTCTTCTACCACTCCTACTATTCCTTATACGATCAATACAGTTGCTGAGCACTTGGATATGCTCATGACTTGC
CACCACTTGGATAAGCGCATCCGCGAGGATTTGCAATTCTCCCAAAGCCGCATCCGCCCTGGATCTATCGCAGCTGAGGA
TACGCTTCATGATATGGGTGTGATTGCAATGACTAGCTCTGACTCTCAAGCAATGGGGCGCGCAGGAGAGGTGATCCCTA
GAACCTGGCAAACTGCTGACAAAAACAAAAAAGAATTTGGTCGCTTGACAGAAGAAAAGGGGGATAATGACAACTTCCGC
ATCAAGCGCTATATCTCTAAATACACCATCAACCCAGCCATCACTCATGGCGTGAGCGAATACATCGGCTCTGTAGAAGA
GGGCAAAATCGCTGATTTGGTGGTTTGGAATCCTGCATTCTTTGGTGTAAAACCCAAAATCATCATCAAGGGCGGAATGG
TGGTATTCTCTGAAATGGGTGACTCCAACGCTTCTGTGCCGACTCCGCAACCTGTTTATTACCGTGAAATGTTTGGACAT
CATGGAAAGGCGAAATTTGACACAAGCATCACTTTTGTCTCTAAAGTCGCTTACGAAAATGGCATCAAAGAAAAACTTGG
CTTGGAAAGAAAGGTTTTGCCCGTCAAAAATTGCCGTAATGTCACCAAAAAAGATTTCAAATTCAATAACACCACAGCCA
AAATCACTGTGAATCCTGAAACCTTTGAAGTTTTTGTAAATGGCAAACTCTGCACCTCCAAACCTGCTACTGAAGTAGCT
TTGGCTAGCCGCTATACATTCTTCTAA

Protein sequence :
MKMKRQEYVNTYGPTTGDKVRLGDTDLWAEVEHDYTVYGEELKFGAGKTIREGMGQSNSPDENTLDLVITNALIIDYTGI
YKADIGIKNGKIHGIGKAGNKDMQDGVTPHMVVGVGTEALAGEGMIITAGGIDSHTHFLSPQQFPTALANGVTTMFGGGT
GPVDGTNATTITPGVWNLHRMLRAAEEYGMNVGLLGKGNSSSRAQLVEQVKAGAIGFKLHEDWGTTPSAIDHCLSVADEY
DVQVCIHTDTVNEAGYVDDTLRAMNGRAIHAYHIEGAGGGHSPDVITMAGEVNILPSSTTPTIPYTINTVAEHLDMLMTC
HHLDKRIREDLQFSQSRIRPGSIAAEDTLHDMGVIAMTSSDSQAMGRAGEVIPRTWQTADKNKKEFGRLTEEKGDNDNFR
IKRYISKYTINPAITHGVSEYIGSVEEGKIADLVVWNPAFFGVKPKIIIKGGMVVFSEMGDSNASVPTPQPVYYREMFGH
HGKAKFDTSITFVSKVAYENGIKEKLGLERKVLPVKNCRNVTKKDFKFNNTTAKITVNPETFEVFVNGKLCTSKPATEVA
LASRYTFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-149 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-149 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-143 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-142 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-142 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-142 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB2 YP_003517278.1 urease subunit alpha VFG0270 Protein 0.0 75