Gene Information

Name : fliI (HMU10250)
Accession : YP_003517010.1
Strain : Helicobacter mustelae 12198
Genome accession: NC_013949
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1161913 - 1163217 bp
Length : 1305 bp
Strand : +
Note : -

DNA sequence :
ATGTCTTTGCAAAGCATCAAAGCAAAACTAGAAGCCCCCCTACAACTCTCTCCAAAATTTGGATTGGTCGAGAAAATCAC
CCCCACCATTCTCTATGCCTCAGGCCTCACACCCAGCATCGGGGACATCGTCTGTGTGCATCGAGAGGATGGAAGTTCAG
GGCTTGGGATGGTCACCCTCTGTCAAAGCGAAAATTTTGGCTTCACCCCCTTCTCTTTCATCGAAGGTTACAAAGTAGGG
GACAAAGTTTTTATCGAAAAGGAGGGCTTTTTGCTGCCCGTTGGAAAGGATGTGCTTGGACGGGTGATTGACCCTTTAGG
AAATCCTATCGATGAGAAAGGCCCTATTACCACAAGTGCACACATCCCCATCATCTCCCAACCCATCAAAGCCATGAGGC
GCGGGGTGATTGATGAGGTTTTTTCTGTGGGGATCAAGGCTATCGATGGCCTTCTCACCTGCGGCAAGGGGCAAAAACTT
GGGATTTTTGCGGGATCTGGAGTGGGAAAATCTACATTGATGGGGATGATTGTCAAAGGCTCCAAGGCCCCCATCAAGGT
CGTGGCACTCATTGGGGAACGGGGGCGGGAGGTGCCAGAATTCATCCAAAAAAACCTAGATAACAATCTAGAAAACACCG
TGATTGTCGTAGCAACCAGTGATGACTCTGCACTCATGCGCAAATATGGGGCATTTTCTGCTATGGCGGTGGCAGAATTT
TTCAAAAATCAAGGGCATGATGTTTTGTTCATCATGGATTCGGTTACACGTTTTGCCATGGCACAGCGAGAGATCGGGCT
AGCCCTTGGTGAGCCACCCACTAGCAAGGGTTACCCTCCTTCGGTTTTGGCATTGCTTCCGCAGTTGATGGAGCGAGCTG
GGAAGGAAGAAGGTCGGGGGTCAATCACGGCATTTTTCACTGTATTGGTGGAAGGAGATGATCTAAGCGATCCTATTGCC
GATCAGAGTCGCAGCATCCTAGATGGCCATATTGTGCTTAGTCGCGAGCTCACAGATTTTGGGATCTATCCCCCCATCCA
CATTCTCAATTCCGCCTCCAGAGTGAGCAATGACATCATCACAAAAGAACACAGGAATGCAGCCAAGAATTTTCGCAAGC
TCTATGCCCTACTCAAAGAAAATGAGGTTTTAATCCGCATTGGTTCTTATCAAAAGGGCACAGATCCCGATCTAGATGAG
GCCATTGAGAAAAAAAAGTTTATGGAGGATTTTATCACTCAAGAAGAAGATCAGCTCTTTGATTTTGATGCGATCATAGA
AGAACTCTACAAAATCCAGCAATAA

Protein sequence :
MSLQSIKAKLEAPLQLSPKFGLVEKITPTILYASGLTPSIGDIVCVHREDGSSGLGMVTLCQSENFGFTPFSFIEGYKVG
DKVFIEKEGFLLPVGKDVLGRVIDPLGNPIDEKGPITTSAHIPIISQPIKAMRRGVIDEVFSVGIKAIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMIVKGSKAPIKVVALIGERGREVPEFIQKNLDNNLENTVIVVATSDDSALMRKYGAFSAMAVAEF
FKNQGHDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSVLALLPQLMERAGKEEGRGSITAFFTVLVEGDDLSDPIA
DQSRSILDGHIVLSRELTDFGIYPPIHILNSASRVSNDIITKEHRNAAKNFRKLYALLKENEVLIRIGSYQKGTDPDLDE
AIEKKKFMEDFITQEEDQLFDFDAIIEELYKIQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-76 52
escN AAK26715.1 EscN Virulence LEE Protein 8e-80 50
escN AAL57542.1 EscN Virulence LEE Protein 8e-80 50
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-80 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-80 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-80 50
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-80 50
escN AAC38383.1 EscN Virulence LEE Protein 4e-80 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-80 48
escN AAC31513.1 L0034 Virulence LEE Protein 3e-80 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-80 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-79 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-80 48
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-79 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-71 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 45
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 9e-84 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 9e-84 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-84 45
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-74 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 6e-74 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-82 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 6e-82 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-59 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-71 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-71 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-71 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-58 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-57 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-57 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-57 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-57 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-58 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-57 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-58 43
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-70 42
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-70 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-64 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-54 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-54 42
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 9e-54 41
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-59 41
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-59 41
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0192 Protein 1e-82 52
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0048 Protein 1e-80 52
fliI YP_003517010.1 flagellum-specific ATP synthase VFG1254 Protein 2e-75 50
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0730 Protein 2e-80 49
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0812 Protein 2e-80 48
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0390 Protein 1e-82 46
fliI YP_003517010.1 flagellum-specific ATP synthase VFG2331 Protein 4e-73 44
fliI YP_003517010.1 flagellum-specific ATP synthase VFG2144 Protein 2e-76 44
fliI YP_003517010.1 flagellum-specific ATP synthase VFG1008 Protein 4e-62 44
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0515 Protein 3e-71 43
fliI YP_003517010.1 flagellum-specific ATP synthase VFG0555 Protein 2e-57 43
fliI YP_003517010.1 flagellum-specific ATP synthase VFG1778 Protein 2e-61 42