Gene Information

Name : Snas_5372 (Snas_5372)
Accession : YP_003514097.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 5707696 - 5709129 bp
Length : 1434 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: dia:Dtpsy_1158 mercuric reductase

DNA sequence :
ATGACCGACTACCGCACTCACGATCTGGCGATCATCGGTTCAGGCGGCGGAGCGTTCGCTGCCGCCATCGCCGCCCGAAA
GCAGGGTCTGTCGGTGGTGATGGTCGAGGCGGGCGCTGTCGGTGGCACTTGTGTCAATACCGGATGCGTGCCCTCGAAAG
CGCTATTGGCTGCCGCCGAAGCACGCCATCAAGCCCAGGGCTCCCGGTTCGCCGGGGCGCCCACCCGTGCCGGGGCGGTG
AGCTGGCGCGAGTTGCGCGCGTCCAAGGACGATCTCGTGGCCGCCATGCGGGCCGACAAGTACACCGGCCTGGCAGCCGA
GTACGGATGGGAGATCGTGGCCGAGACCGCGGCCTTCGCCGGCACGCCCGATGCTCCGGCGATCGAGGTGACACTGCATG
ACGGTGGCGGCCGCCGGCTTCAGGCGAGCCACTACGTGATCGCCACCGGCTCGATCCCGTGGGTGCCACCGATTCCCGGA
CTGGCCGAAGCCGGGTACCTCACCTCCACCACCGCGATGGATCTGGAGGAGCTTCCTGAGTCGCTGATCGTGATCGGCGG
CAACGCCATCGGCCTGGAACAAGCCCAGCTGTTCGCTCGCCTCGGTGTGAAAGTCACCATCGTGGAAGCCCTGGACCGCC
TGGCGCCGTTCGAGGAACCTGACATCTCGTCCGTCGTCGAACACGCTCTTGCGGACGAGGAGGTCGACGTGGTCACCGCG
GCGGTCGTCACCAAGGTCCACACTAGACCCGGTGGCTATGCCGTCGAGGTGATCGGCCCCGATGGAGCGGTCCGGCAGCT
GGCGGGCGAACGGCTTCTGGTGGCTACCGGTCGCCGCCCCAATACCGCCGGGCTCAGGCTCGCGTCAGTGGGTGTCGAAG
TGGGCGACCGCGACGAGGTGATCGTCGACGACCGGCTGCGCACGGCAAACCCTCGCATCTGGGCGGCCGGCGACGTCACC
GGGCATCCCCAGTTCGTCTACGTAGCGGGCAGACACGGGAGCGTGATAGTGGACAACGCCTTCAACGAAGCGAACCGCAC
TGTGGACCATTCTCATCTCCCCCGGGTCACGTTCACCTCCCCGACGGTCGCTTCGGTCGGCCTCACCGACGCCCAGGCAG
TCGCGGCCGGGTATACCTGTGAATGCCGAGTCCTCCCCCTGGAATACGTGCCGCGTGCCGTCGTCGACCGCGACACCATC
GGTGTCGTCAAACTCGTCGCCGACGCCAACACCGGACGACTCCTGGGCGCCCACATCGCCGCCAAGGCCGCCGGGGACAT
GATCCTCGCCGCCACGTACGCCCTCGATCACGGCATGACCGTCGCCGACATGGCCGACGCCTGGTGCCCCTACCTCACCT
GGGCAGAGGCACTGAAACTCACAGCCCAGACGTTCACCACCGACGTCACCAAACTCTCCTGCTGCGCCGCATGA

Protein sequence :
MTDYRTHDLAIIGSGGGAFAAAIAARKQGLSVVMVEAGAVGGTCVNTGCVPSKALLAAAEARHQAQGSRFAGAPTRAGAV
SWRELRASKDDLVAAMRADKYTGLAAEYGWEIVAETAAFAGTPDAPAIEVTLHDGGGRRLQASHYVIATGSIPWVPPIPG
LAEAGYLTSTTAMDLEELPESLIVIGGNAIGLEQAQLFARLGVKVTIVEALDRLAPFEEPDISSVVEHALADEEVDVVTA
AVVTKVHTRPGGYAVEVIGPDGAVRQLAGERLLVATGRRPNTAGLRLASVGVEVGDRDEVIVDDRLRTANPRIWAAGDVT
GHPQFVYVAGRHGSVIVDNAFNEANRTVDHSHLPRVTFTSPTVASVGLTDAQAVAAGYTCECRVLPLEYVPRAVVDRDTI
GVVKLVADANTGRLLGAHIAAKAAGDMILAATYALDHGMTVADMADAWCPYLTWAEALKLTAQTFTTDVTKLSCCAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 9e-90 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 7e-90 45
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-67 42
merA ABQ57371.1 MerA Not tested SGI1 Protein 3e-68 41
merA AGK07021.1 MerA Not tested SGI1 Protein 3e-68 41
merA AGK07079.1 MerA Not tested SGI1 Protein 3e-68 41
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-68 41
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-68 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_5372 YP_003514097.1 mercuric reductase BAC0224 Protein 2e-87 46
Snas_5372 YP_003514097.1 mercuric reductase BAC0651 Protein 4e-90 45
Snas_5372 YP_003514097.1 mercuric reductase BAC0652 Protein 1e-68 41