Gene Information

Name : Snas_5357 (Snas_5357)
Accession : YP_003514083.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Resistance
Product : D-Ala-D-Ala dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : 3.4.13.22
Position : 5693804 - 5694412 bp
Length : 609 bp
Strand : +
Note : PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; KEGG: sfu:Sfum_0509 peptidase M15D, VanX D-ala-D- ala dipeptidase

DNA sequence :
ATGAGCGACGACTTTGTCTTCGTGGACGAGGCCGTTCCCGGAATCCGTTGGGACGCCAAGTACGCCACCTGGGACAACTT
CACCGGCAAACCGGTCGACGGCTACCTGGTCAACCGCATCCTGGGCACCCGCGCGCTATGCGCGGCTCTCGAACGAGCCC
GCAAAGAAGCCGCGTCCCTCGACTTCGGCCTACTCCTGTGGGACGGCTACCGCCCCCAACGCGCCGTCGACCGCTTCATG
CGCTGGTCAGAACAACCCGAAGACGGCCGCACCAAACGACGCCACTACCCGAACATAGCCAGAACCGAAATGTTCGAACT
AGGCTATGTAGACGCCAAATCCGGCCACAGTCGAGGCAGCACCGTCGACCTCACCCTCTACCACCTGGCCACCGGCGAAC
TCGTCCCCATGGGCGGCGACCACGACCTGATGGACCCGGTCTCCCACCACGGAGCGACCGGAATCACCCCAACCGAAGCC
GAGAACCGCCGCCACCTCCGCTCCATCATGGAGACCGCCGGTTTCCGCGCGTACCCCTACGAATGGTGGCACTACACGCT
GGAGGACGAGCCCTACCCCGACACCTACTTCGACTTCCCCATCACATGA

Protein sequence :
MSDDFVFVDEAVPGIRWDAKYATWDNFTGKPVDGYLVNRILGTRALCAALERARKEAASLDFGLLLWDGYRPQRAVDRFM
RWSEQPEDGRTKRRHYPNIARTEMFELGYVDAKSGHSRGSTVDLTLYHLATGELVPMGGDHDLMDPVSHHGATGITPTEA
ENRRHLRSIMETAGFRAYPYEWWHYTLEDEPYPDTYFDFPIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 1e-63 64
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 3e-64 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase U82965.2.orf32.gene. Protein 2e-82 85
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase AF155139.2.orf6.gene Protein 2e-65 67
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase AF130997.1.orf5.gene Protein 5e-66 66
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase M97297.gene.p01 Protein 2e-63 65
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase NC_014475.1.orf4.gen Protein 2e-63 65
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase NC_005054.2598281.p0 Protein 2e-63 65
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase AF310956.2.orf6.gene Protein 4e-64 64
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase AE016830.1.gene2249. Protein 8e-65 64
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase U35369.1.gene7.p01 Protein 2e-64 64
Snas_5357 YP_003514083.1 D-Ala-D-Ala dipeptidase FJ349556.1.orf5.gene Protein 1e-61 63