Gene Information

Name : Snas_5355 (Snas_5355)
Accession : YP_003514081.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Resistance
Product : NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 5691815 - 5692774 bp
Length : 960 bp
Strand : +
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bmj:BMULJ_00680 D-lactate dehydrogenase

DNA sequence :
ATGGGAATCACGGTCTACGGCTGCGGACAGGACGAGGCCGTCCTGTTCCGCGAGATGTCACCCAGCTACGGCGTGACCCC
CACGATCACCCCGGCACCGCTAACCGAAGCCAACGTCGAACTCGCCTTCGGCAACCGCTGCGTCAGCGTCGGTCACAAGA
CCCGAATCACCGATGCCACCCTCCGCGCGCTCAACCGAATCGGCACAAACTACATCTCCACCAGGAGCATCGGCTACAAC
CACATCAATGTGGACTACGCCAAAACCCTGGACATCACCGTCGAGAACGTCTCCTACTCCCCCGACAGCGTCGCCGACTA
CACCCTGATGCTCATGCTGATGGTGGTGCGCAGCGCCAAATCCATCATCCGCCGCACCGACGTCCACGACTACCGGCTCA
ACGACGTATGCGGCAGAGAACTACGCGACCTCACCGTCGGCGTCATCGGCACCGGACGAATCGGCGCCGCCGTCATGGAC
CGACTGTGGGGCTTCGGTTGCCGCGTCCTCACCCACGATCGCCGTCACAAGACCGGCGCCGACCACGTCCCCCTCGACCA
ACTGCTGCGCCAAAGCGACATGGTCACGCTCCACACACCACTGAACGCGAGCACCCACCACCTCCTCAACCGCACCCGCC
TCGAGCAGATGAAACCCGGCGCCTACGTCATCAACACCGGACGCGGCTCCCTCATCGACACCGAAGCCCTGGTCCCCGCA
CTGGAGAGCGGCCGCTTGGGTGGTGCGGCCCTGGACGTCATCGAGGGCGAAGAGGGCGTCTTCTACGCCGACTGCCGCAA
CAAGGTCATCGAGAGCAAATCCCTGCTGCGACTACAAGAACTGCCCAATGTGCTCATCAGCCCGCACACGGCCTACTACA
CCGACCACGCCCTGAGCGACACGGTCGAGAACTCCATCATCAATTGCCAGAAATTCGAGAACAGGAACCAGCATGGCTAA

Protein sequence :
MGITVYGCGQDEAVLFREMSPSYGVTPTITPAPLTEANVELAFGNRCVSVGHKTRITDATLRALNRIGTNYISTRSIGYN
HINVDYAKTLDITVENVSYSPDSVADYTLMLMLMVVRSAKSIIRRTDVHDYRLNDVCGRELRDLTVGVIGTGRIGAAVMD
RLWGFGCRVLTHDRRHKTGADHVPLDQLLRQSDMVTLHTPLNASTHHLLNRTRLEQMKPGAYVINTGRGSLIDTEALVPA
LESGRLGGAALDVIEGEEGVFYADCRNKVIESKSLLRLQELPNVLISPHTAYYTDHALSDTVENSIINCQKFENRNQHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-89 56
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-88 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein NC_005054.2598279.p0 Protein 6e-93 57
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein NC_014475.1.orf2.gen Protein 6e-93 57
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein AF155139.2.orf4.gene Protein 1e-94 57
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein U35369.1.gene5.p01 Protein 6e-90 56
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein FJ349556.1.orf3.gene Protein 2e-89 56
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein AF310956.2.orf4.gene Protein 6e-89 55
Snas_5355 YP_003514081.1 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein AF130997.1.orf3.gene Protein 3e-81 55