Gene Information

Name : Snas_4516 (Snas_4516)
Accession : YP_003513254.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 4816768 - 4818321 bp
Length : 1554 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce3880 (2,3-dihydroxybenzoyl)adenylate synthase

DNA sequence :
ATGAACGCGCCGTTCACGCCATGGCCTGAGGACATCGCCGCCGACTACCGCGACCAGGGACTGTGGACGGGAGAGCCGTT
CTCGCTGCTGCTGGAACGGTTGGCCGCCAAGCACGGTGACCGGGTCGCCGTTACCGACGGCGACTGCTGGCTGTCGTACG
AGTCGCTGCTGGAGCGCTCCCGGCGGGTGGCCGCCGGACTGCACCAGCGGGGTCTGCGGCCGGGTGACATCGTCGTGATG
CAGGCGGCCAACACCAGCGAATACCTCGTGGTGTTGTTCGCGTTGTTCCGGCTAGGCGTGGCACCGGTGTGCGCGCTACC
GGCGCACCGCGAGGCCGAGATCGGTTACTTCGCCGAGCACACCAAGGCCGCGGCCTACCTGCATCCCGGTGGCGCCGAGT
ACGACCGCATCGCCGCGAGTCTCGACGTCACGCACGTGTGGACCGTCGAGCAGGCCGCCAAGACCTACGCCGACCCGGCG
GGGCTGCCACCCGCCCCCCGTGGCGGGGATCTGGCGCTGCTGCAACTGTCGGGCGGCTCCACCGGGGTGCCGAAACTGAT
TCCGCGCACCCACGACGACTACCTCTACAGTGTCCGCGTCGCCGCCGAGGTCTGCGAACTGACACCGGCCACGGTGTACC
TGTGCGCGTTGCCGGTGGCGCACAACTTCCCACTGTCCTCCCCCGGCGTGCTGGGGGTGCTGTACGCGGGCGGCACCGTC
GTGATGGCCCCCGATCCCAGTCCCGACACCGTTTTCCCGCTCATCGTGTCCGAGGGCGTCACCATGACCGCGGTGGTGCC
GGCGCTGGCGCTGACCTGGCTGCGGGCCGCCGAGGCCCGGGGCGCGGAACTGCCGAGCCTGGAGGTGTTGCAGGTCGGCG
GGGCCCGGCTGGGCGACGCCGACGCCGAACGGGTGACGCCGGTGCTGGGCGCGAAACTGCAGCAGGTCTTCGGAATGGCC
GAGGGCCTGGTCTGCTACACCCGGCTCGACGATCCCTTCGCGACGGTGTGCGCTACCCAGGGCCGTCCGGCCTCGGAGGC
CGACGAGGTCCGCATCGTCGACGACGCCGACGAACCGGTGCCCGAAGGCCACAGTGGGCACCTGTTGACGCGCGGGCCCT
ACACGATCCGCGGCTACTACCGGGCCGATGCCCACAACGCCACCGCGTTCACGAGCGACGGTTTCTATCGCACCGGGGAC
CTGGTGCGCCGCACCGAAACCGGGCACCTCATCGTCACCGGCCGGGCCAAGGAGCAGATCAACCGGGGCGGCGAGAAGAT
CGCCACCGCCGAGATCGAGGAGCACCTGCGCACCCACCCCGGCATCCACGACGCGGCCCTGGTCGCCGTCCCCGACGACG
CGCTGGGTGAACGCGCCTGCGCCTTCTGCGTCACCGACGGCGAACTGACCGCCAAACAGGTGCGCGCCCACCTTCGCGGC
CGGGGCCTGGCCGCGTACAAGATCCCCGACCTCGTCCGCTTCGTCGCCAGCCTTCCCCGAACGCCCGTGGGAAAGATCGA
CAAGAACCGTCTAAAAGAGAGTGTGAATCTATGA

Protein sequence :
MNAPFTPWPEDIAADYRDQGLWTGEPFSLLLERLAAKHGDRVAVTDGDCWLSYESLLERSRRVAAGLHQRGLRPGDIVVM
QAANTSEYLVVLFALFRLGVAPVCALPAHREAEIGYFAEHTKAAAYLHPGGAEYDRIAASLDVTHVWTVEQAAKTYADPA
GLPPAPRGGDLALLQLSGGSTGVPKLIPRTHDDYLYSVRVAAEVCELTPATVYLCALPVAHNFPLSSPGVLGVLYAGGTV
VMAPDPSPDTVFPLIVSEGVTMTAVVPALALTWLRAAEARGAELPSLEVLQVGGARLGDADAERVTPVLGAKLQQVFGMA
EGLVCYTRLDDPFATVCATQGRPASEADEVRIVDDADEPVPEGHSGHLLTRGPYTIRGYYRADAHNATAFTSDGFYRTGD
LVRRTETGHLIVTGRAKEQINRGGEKIATAEIEEHLRTHPGIHDAALVAVPDDALGERACAFCVTDGELTAKQVRAHLRG
RGLAAYKIPDLVRFVASLPRTPVGKIDKNRLKESVNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-97 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-95 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-96 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-96 49
ybtE CAA21394.1 - Virulence HPI Protein 9e-96 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-97 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-96 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_4516 YP_003513254.1 AMP-dependent synthetase and ligase VFG0168 Protein 2e-109 50
Snas_4516 YP_003513254.1 AMP-dependent synthetase and ligase VFG0932 Protein 5e-102 47
Snas_4516 YP_003513254.1 AMP-dependent synthetase and ligase VFG1817 Protein 1e-90 45