Gene Information

Name : Snas_4099 (Snas_4099)
Accession : YP_003512843.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Resistance
Product : 3''-kinase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG3231
EC number : 2.7.1.87
Position : 4372185 - 4373006 bp
Length : 822 bp
Strand : +
Note : PFAM: aminoglycoside phosphotransferase; KEGG: aby:ABAYE3648 streptomycin 3''-kinase (streptomycin 3''-phosphotransferase) (streptomycin 6- phosphotransferase) (streptomycin 6-kinase)

DNA sequence :
ATGATCGATCCTCCTGAAGCTTGGACCGCGTCGTCGGTGCTGCTTGGGGTGGACGAGGGTGCCTGGTTGCCTATCACCAC
AGGCCAATCGGGAGCTGCCGTCTTTCGGAGCGCGGACGGCACCCGGTTTGCCAAGTGCGTGCCCGCTGCGGATGCCGCCG
AGTTGCAGGACGAGCGTGACCGAACCACTTGGCTGAACGATCAGGGTGTGCCTGGTCCTCGGGTGCTTGATTGGCGTTCT
GGGGAGGCGGGCGCTTGTCTGGTGACCACGGCCGTGTCCGGCGTACCCGCTGATCAAGTGTCCAGCGAGGACCTGCGACG
GGCTTGGGGAAGCATCGCGGACGCGCTTCGTCAGTTGCATGAGCTGCCGGTTTCGCAGTGCCCGTTCCGTTGGGGCTTGG
ATTCCATGGTCGCTTTGGCGCGTGACGTTGTGGCTCGTGATGCCGTCAATCCGGAGTTTCTTCCCGTCGAGCAGCGGGGC
ACTCCCGCCGCGGAGTTGTTGGAGCGCATCGTTGCGCAGGTTCCGCAGCGACGGGAGCAGGAGGCCGCCGACACTGTGGT
CTGTCACGGGGATTTGTGTCTTCCCAACATCATTCTTGATCCGGAGACTTTGGACGTGGCGGGGTTTATCGATCTGGGCC
GCCTCGGGCTGGCCGATCGCTACATCGACGTGGCTCTGTTGCTGACCAACGCGCGAGAGAACTGGACCGACGAGGAGCAG
GCACGGACAGCGGACGTGGCGTTCGCTGAGAAGTACGGCATCGACTTGGACCACGACCGTCTGCGCTTCTATCTCCATCT
CGATCCGCTCACGTGGGGTTAA

Protein sequence :
MIDPPEAWTASSVLLGVDEGAWLPITTGQSGAAVFRSADGTRFAKCVPAADAAELQDERDRTTWLNDQGVPGPRVLDWRS
GEAGACLVTTAVSGVPADQVSSEDLRRAWGSIADALRQLHELPVSQCPFRWGLDSMVALARDVVARDAVNPEFLPVEQRG
TPAAELLERIVAQVPQRREQEAADTVVCHGDLCLPNIILDPETLDVAGFIDLGRLGLADRYIDVALLLTNARENWTDEEQ
ARTADVAFAEKYGIDLDHDRLRFYLHLDPLTWG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
strA YP_005176180.1 aminoglycoside 3''-phosphotransferase protein Not tested ICEPmu1 Protein 6e-56 51
strA AFV47972.1 streptomycin (3') phosphotransferase StrA Not tested AbaR25 Protein 1e-58 50
strA AFV48000.1 streptomycin (3') phosphotransferase StrA Not tested delta-AbaR25 Protein 1e-58 50
strA ACK44539.1 StrA Not tested SGI1 Protein 1e-58 50
strA AEA34675.1 aminoglycoside phosphotransferase Not tested Not named Protein 1e-58 50
strA YP_001800932.1 aminoglycoside-3''-phosphotransferase Not tested Not named Protein 1e-58 50
strA AFH57207.1 streptomycin resistance protein Not tested AbaR4a Protein 1e-58 50
strA AEQ20909.1 StrA, APH(3')-Ib streptomycin(3') phosphotransferase Not tested Tn6166 Protein 1e-58 50
strA AGK07031.1 StrA streptomycin phosphotransferase Not tested SGI1 Protein 1e-58 50
strA AEZ06049.1 StrA, APH(3')-Ib, streptomycin(3') phosphotransferase Not tested Tn6167 Protein 1e-58 50
strA AGK07089.1 StrA streptomycin phosphotransferase Not tested SGI1 Protein 1e-58 50
strA CAJ77025.1 Streptomycin phosphotransferase A Not tested AbaR1 Protein 7e-59 50
BJAB07104_00282 YP_008207747.1 Aminoglycoside phosphotransferase Not tested AbaR25 Protein 1e-58 50
ABZJ_00266 YP_005524222.1 hypothetical protein Not tested AbaR22 Protein 1e-58 50
ABK1_0266 YP_005512838.1 StrA Not tested AbaR4d Protein 1e-58 50
BJAB0868_00286 YP_008211612.1 Aminoglycoside phosphotransferase Not tested AbaR26 Protein 5e-58 49
ABK1_0258 YP_005512830.1 StrA Not tested AbaR4d Protein 1e-58 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_4099 YP_003512843.1 3''-kinase DQ336355.1.orf1.gene Protein 4e-58 56
Snas_4099 YP_003512843.1 3''-kinase AF024602.1.gene5.p01 Protein 7e-59 50