Gene Information

Name : Snas_1499 (Snas_1499)
Accession : YP_003510296.1
Strain : Stackebrandtia nassauensis DSM 44728
Genome accession: NC_013947
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1581608 - 1582762 bp
Length : 1155 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pzu:PHZ_c0072 cystathionine gamma-lyase

DNA sequence :
ATGCCCATGACCAAGGACTTTCCGGGCTTTTCCACGCGCGCCATTCACGCCGGACAGGAGGCCGACCCCCGCACGGGCGC
GGTCGTGCCCCCGATCTACGCCACCTCCACCTACAAGCAGGACGGCGTGGGCGGCATGCGCGAGGGCTACGAATACAGCC
GCACCAAGAACCCGACCAGGCGAGCTCTCGAGGAATGCCTTGCGGCACTTGAGGAAGGGCGTCACGGCTTCGCCTTCGCC
TCCGGTATGGCCGCCGAGGACACCCTGTTGCGTACCGTGTGCCAGCCCGGCGATCACGTCGTGATCCCTGGCGATGCGTA
TGGCGGGACGTTCCGGCTGTTCGACAAGGTCGCGACCCGTTGGGGGCTGAACTACACGCCCGCGAAGTCCTCGGACGTCG
ATGGGGTGCTGGCCGCGATCACGCCGAACACGAAGATCGTGTGGGTCGAGACGCCGACCAACCCGCTGCTCAACATCACC
GACATCGCCGCTGTGGCCGCTGTCGCGCATCAGGCGGGGGCGATTTTGGTTGTGGACAACACTTTCGCGTCGCCGTATTT
GCAGCAGCCGTTGGTGCTTGGGGCGGATGTGGTGGTTCATTCGACGACGAAGTACGTGGGCGGGCATTCGGATGTGGTGG
GGGGCGCGTTGGTGGTCAACGACGATGTGTTGGCCGAGGGTTTGGCGTTCCACTCGAACTCGATGGGGGCGATTTCGGGG
CCGTTCGACGCCTGGTTGACGTTGCGCGGGGCGAAGACCTTGGGGGTTCGGATGGATCGGCACTGTGACAATGCCGAGAA
GATCGTGGGGTGGCTGGGCCAGCGGGAGGAGGTCGCGGAGATCTTCTACCCGGGGTTGGAGACGCATCCCGGGCATGACA
TCGCGGTGAAGCAGATGCGGCGGTTCGGCGGGATGGTGAGTTTCCGGATGGCGGACGGTGAGGATGCCGCGCTGCGGGTG
TGCAACAGCGCTGAGTTGTTCACGTTGGGGGAGTCGTTGGGTGGGGTGGAGTCGCTCATCGAGCATCCCGGGCGGATGAC
GCATGCCTCGGCGGCGGGTTCGCCGTTGGAGGTGCCGTCGGATCTGGTGCGGTTGTCGGTGGGGATCGAGGATGTCGAGG
ACCTCATCGCTGATTTGGCGCGGGCGTTCGGGTGA

Protein sequence :
MPMTKDFPGFSTRAIHAGQEADPRTGAVVPPIYATSTYKQDGVGGMREGYEYSRTKNPTRRALEECLAALEEGRHGFAFA
SGMAAEDTLLRTVCQPGDHVVIPGDAYGGTFRLFDKVATRWGLNYTPAKSSDVDGVLAAITPNTKIVWVETPTNPLLNIT
DIAAVAAVAHQAGAILVVDNTFASPYLQQPLVLGADVVVHSTTKYVGGHSDVVGGALVVNDDVLAEGLAFHSNSMGAISG
PFDAWLTLRGAKTLGVRMDRHCDNAEKIVGWLGQREEVAEIFYPGLETHPGHDIAVKQMRRFGGMVSFRMADGEDAALRV
CNSAELFTLGESLGGVESLIEHPGRMTHASAAGSPLEVPSDLVRLSVGIEDVEDLIADLARAFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-74 48
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-73 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-51 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Snas_1499 YP_003510296.1 cystathionine gamma-synthase BAC0207 Protein 6e-60 42