Gene Information

Name : Mrub_0887 (Mrub_0887)
Accession : YP_003506672.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_013946
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 872949 - 875513 bp
Length : 2565 bp
Strand : +
Note : TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; InterProIPR001270:IPR010448:IPR003959:IPR

DNA sequence :
ATGAATCTGGAGCGCTATACCGAACAAGCCCGCCAAGCCATTGCCCAAAGCCAGGTGCTGGCCCGGGAGTCGGCCCATTC
GCAGATCGACCTGCCGCACCTGGCCGCGGTGATGCTGCGGGACGCTGCGGGTCTGCCGGCCAAGATTGTGCAAAAAGCCG
GGCAGAACCCCCAGAATATCTACCAGGCCGCCCAGAGCGAACTGGGTCGGCTGCCCAAGGTTTCGGGCACCGAGGGGGGG
CAGTACCTCTCGTCCCGCCTGGCCTCGGCGCTGGGGCGGGCTGAAAAGCTGGCCGATGAGCTGAAAGATCGCTTTGTGGC
CCTGGACACGCTGCTTCTGGCCCTGGCCGAGACCGGGTATGGGGGGTTGCAGGCCAGCGCGGTTCGGCAAGCCCTACAGG
AGATCAGAGGAGGAAGAACCGTGAACAGCGAACACGCCGAAGGAACCTACAACGCCCTCGAGCAGTACGGCCTCGACCTG
ACCCGCCAGGCCGAGGAGGGCAAGCTCGACCCCGTGATCGGGCGCGACGAAGAGATCCGGCGGGTAATTCAAATTCTGCT
GCGCCGCACCAAGAACAACCCGGTGCTGATTGGTGAGCCGGGGGTGGGTAAGACCGCCGTGGTGGAAGGGCTGGCCCAGC
GCATCGTGAAGGGCGACGTGCCCGAGGGGCTCAAGGGCAAGCGCATCGTGAGCCTGCAGATGGGCTCGCTGCTGGCCGGG
GCCAAGTACCGCGGCGAGTTTGAAGAGCGGCTCAAGGCCGTCATCCAGGAGACCGTGCAGAGCGCGGGCCAGATTATTCT
ATTCATCGACGAGATTCACACCGTGGTGGGGGCCGGCAAGGCCGAGGGCGCGGTGGACGCAGGCAACATGCTCAAGCCGG
CCCTGGCCCGGGGCGAGCTACACCTGATCGGGGCCACCACCCTCGACGAGTACCGCGAGATCGAGAAAGACCCGGCCCTG
GAGCGCCGCTTCCAGCCGGTGTTTGTGGACGAGCCCAGCCTCGAGGAGACCGTCAGCATCCTGCGCGGTATCAAGGAGAA
GTACGAGGTGCACCACGGGGTGCGCATCTCCGACCCGGCGCTCATCGCGGCGGCCCAGCTCTCGCACCGCTACATCGCCG
ACCGCAAGCTGCCCGATAAGGCCATCGACCTGGTGGACGAGGCGGCGGCCCGGCTGCGCATGGCCCTCGAGAGCAGCCCC
GAGAGCATTGATGCCCTGAACCGCCGGAAGCTCCAGCTCGAGATCGAGCGCGAGGCCCTGAAAAAGGAGACCGACGCCGA
GAGCAAGTTCAGGCTGGGCGAGCTGGAAAAGGAAATCGCCGAGCTCGAGGCCGAGATCAAGAAGCAGCAGGCCGAGTGGG
AGGCCGAGCGCGAGATTATGCAGAAGCTCCGCGCGGCCCAGCAGCGCCTGGATGAGGTGCGCACCCAGATCGAGCAGGCC
GAGCGGGCCTACGACCTGAACAAAGCCGCCCAGCTCCGCTACGGTGAGCTGCCAAAGCTCGAGCAGGAGGTCAACGAACT
GGCCGACCGCATGGCCGGGGCCCAGTTTGTGCGGCCCATGGTGACCGAGGAGGACATCGCCGCCATTGTCTCGCGCTGGA
CTGGCATCCCAGTGGCTAAGCTGATGGAGGGTGAGCGCGAGAAGCTCCTGCGCCTCGAGGACGAACTGCACAAGCGGGTG
GTGGGCCAGGACGAGGCCATCGTGGCGGTGGCCGACGCCATCCGGCGGGCCCGCGCCGGCCTCAAAGACCCCAACCGACC
CATCGGCTCCTTCCTCTTCCTGGGCCCCACCGGCGTGGGTAAGACCGAGCTGGCTAAAACCCTGGCCGCCAGCCTCTTCG
ACACCGAAGAGAACATGGTGCGCATTGACATGTCGGAGTACCAGGAGAAGCACACCGTGGCCCGCCTGATTGGGGCCCCT
CCCGGCTATGTGGGCTACGAGGAGGGCGGCCAGCTCACCGAGGCGGTGCGCCGCCGGCCCTACTCGGTGATCCTCTTCGA
CGAGATCGAGAAGGCCCACCCCGACGTGTTCAACGTCCTGTTGCAGGTGCTCGACGACGGCCGCCTGACCGACGGCCAGG
GCCGCACGGTGGACTTCCGCAACACCGTGATTATCCTCACCTCCAACATCGGCTCGCCCCTTATCTTCGAGGGCATCCAG
TCGGGCCAGAGTTACGAGACCATCCGCGAGCGGGTGTTTGGGGTGCTGCAGCAGCACTTCCGCCCCGAGTTCCTCAACCG
CCTCGACGAGATTGTGGTCTTCCGTCCGCTGGCCAGGGAGCAGATCGCGGCCATCGTGCAGATCCAGCTCGAGGCGGTGC
GCAAGCGCCTGGCCGAACGCCGGATTACCCTCGAGCTCTCACAAGAGGCCCTCGACTTCCTGGCCCAGCGCGGCTACGAC
CCGGTCTTTGGGGCTAGGCCCTTGAAGCGGGTGATCCAGCGGGAACTCGAGACCCCCCTCTCGCGCAAGATTCTGGCGGG
CGAGGTGGCCGATGGCGCCCATCTGTACGTGGGCAGCGGCCCCCTGGGCCTCACCTTCGAGGTGCGTCAGGCCGCGGTGG
CCTAA

Protein sequence :
MNLERYTEQARQAIAQSQVLARESAHSQIDLPHLAAVMLRDAAGLPAKIVQKAGQNPQNIYQAAQSELGRLPKVSGTEGG
QYLSSRLASALGRAEKLADELKDRFVALDTLLLALAETGYGGLQASAVRQALQEIRGGRTVNSEHAEGTYNALEQYGLDL
TRQAEEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPEGLKGKRIVSLQMGSLLAG
AKYRGEFEERLKAVIQETVQSAGQIILFIDEIHTVVGAGKAEGAVDAGNMLKPALARGELHLIGATTLDEYREIEKDPAL
ERRFQPVFVDEPSLEETVSILRGIKEKYEVHHGVRISDPALIAAAQLSHRYIADRKLPDKAIDLVDEAAARLRMALESSP
ESIDALNRRKLQLEIEREALKKETDAESKFRLGELEKEIAELEAEIKKQQAEWEAEREIMQKLRAAQQRLDEVRTQIEQA
ERAYDLNKAAQLRYGELPKLEQEVNELADRMAGAQFVRPMVTEEDIAAIVSRWTGIPVAKLMEGEREKLLRLEDELHKRV
VGQDEAIVAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAASLFDTEENMVRIDMSEYQEKHTVARLIGAP
PGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIILTSNIGSPLIFEGIQ
SGQSYETIRERVFGVLQQHFRPEFLNRLDEIVVFRPLAREQIAAIVQIQLEAVRKRLAERRITLELSQEALDFLAQRGYD
PVFGARPLKRVIQRELETPLSRKILAGEVADGAHLYVGSGPLGLTFEVRQAAVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-157 54
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-103 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrub_0887 YP_003506672.1 ATP-dependent chaperone ClpB VFG2076 Protein 4e-112 43
Mrub_0887 YP_003506672.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-104 41