Gene Information

Name : Mrub_0047 (Mrub_0047)
Accession : YP_003505848.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_013946
Putative virulence/resistance : Resistance
Product : major facilitator superfamily protein
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 40126 - 41331 bp
Length : 1206 bp
Strand : +
Note : PFAM: major facilitator superfamily MFS_1; SPTR: A6E7B4 Tetracycline resistance protein; InterPro IPR001958:IPR011701:IPR007114:IPR005829; COGs: COG2814 Arabinose efflux permease; KEGG: rce:RC1_1688 tetracycline resistance protein, class C; PFAM: Major Fa

DNA sequence :
ATGTCGAAGAGCGCCTCTATTCCCTTCATCCTGATTTCGGTACTTATCAACGTGATGGGCCTGGGTCTGGTCATTCCGGT
CTTGCCCAAGCTCATCGAGACCCTGGCCGGCGGCGTGGAGGCCGGGGCCCGGCTCAATGGCCTGTTTTTTGCGGTGTACG
CCGTAATGCAATTCGCCTTTGGCCCCATCCTGGGCATGCTCTCCGACCGCTACGGGCGCCGCCCGGTGCTGCTGGCCTCG
CTGGTGGGCACCGCCGTGGATTACTTGATTGCCGCCCTCACCCAGTCCATCTGGGTGCTGTTTGCGGCGCGGGTGATTGC
CGGGGCATTGGGGGCCAGCCTCTCGACCGCCAACGCCTACATTGCCGATATTTCCAAACCCGAAGAGCGGGCCCGCAACT
TTGGCCTGATTGGGGCTACCTTTGGGATGGGTTTCGTGCTGGGGCCGGTGCTGGGCGGGCTACTGGGCAACATTGACCTG
CGCCTGCCTTTCTACTTTGCGGCGGGACTGGCCTTCCTCAACTTTTTGTATGGCTACTTTGTGCTGCCCGAGTCGCTCAA
GCCGGAAAACCGCAACACCCAGGCCCGCTCGCTCAACCCGTTTGTGGCCCTGGGGATCTTGCGCAAGACCCCCATCCTGC
GGGGGTTATCCCTGAGCCTCGCGCTCATCTTTCTGGCCTTCGGGTCTTTGCAGAGTGTGTGGGTGCTGTACACCGCCTAC
AAGTTTGGCTGGGAGCCGCTCGAGGTGGGCTTCTCGCTGTTTCTGGTGGGCTTGGGCGGGGTGATTGTCCAGGCCGGGCT
GGTTCGGCCCGTGGTGGCCCACCTGGGGGAGCGCCGGGCCCTGACCCTGGCCCAGAGCATGGGGCTGTTCTCCTTCACCT
TGTACGGCCTGGCCACCCAGGGCTGGATGATGTACGCCATCATCGCCCTGGCCGCCCTGAGCAACCTGGGCCAGCCCCTC
ATTCAGTCCTTCCTGACCCGCGAGGTCTCGCCGCAGGAGCAGGGCACCCTGCAAGGGGCGCTGGCCGGGCTGCAAAGCCT
GACGGTGGCGGTGGGCGGTCTTTTGGGTGGGTTCCTCTTTTCGGTGGTGGCGAGGCCCGAGGTGGCCCCCTGGCTGGTGG
GGCTGCCTTTTTTTGTGGGGGCCCTGCTCTACGCCACGGCGGCGGCCAACACCGCCCGGCTGTTTCGCGGCCTGCGAGGC
AGTTAG

Protein sequence :
MSKSASIPFILISVLINVMGLGLVIPVLPKLIETLAGGVEAGARLNGLFFAVYAVMQFAFGPILGMLSDRYGRRPVLLAS
LVGTAVDYLIAALTQSIWVLFAARVIAGALGASLSTANAYIADISKPEERARNFGLIGATFGMGFVLGPVLGGLLGNIDL
RLPFYFAAGLAFLNFLYGYFVLPESLKPENRNTQARSLNPFVALGILRKTPILRGLSLSLALIFLAFGSLQSVWVLYTAY
KFGWEPLEVGFSLFLVGLGGVIVQAGLVRPVVAHLGERRALTLAQSMGLFSFTLYGLATQGWMMYAIIALAALSNLGQPL
IQSFLTREVSPQEQGTLQGALAGLQSLTVAVGGLLGGFLFSVVARPEVAPWLVGLPFFVGALLYATAAANTARLFRGLRG
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 5e-45 44
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 4e-45 44
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 4e-45 43
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 3e-45 43
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 3e-45 43
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 3e-45 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrub_0047 YP_003505848.1 major facilitator superfamily protein NC_011586.7045189.p0 Protein 6e-42 44
Mrub_0047 YP_003505848.1 major facilitator superfamily protein CP001485.1.gene2821. Protein 2e-45 44
Mrub_0047 YP_003505848.1 major facilitator superfamily protein AF534183.gene.p01 Protein 2e-45 44
Mrub_0047 YP_003505848.1 major facilitator superfamily protein NC_010410.6002597.p0 Protein 2e-45 44
Mrub_0047 YP_003505848.1 major facilitator superfamily protein Y19114.gene.p01 Protein 1e-41 42
Mrub_0047 YP_003505848.1 major facilitator superfamily protein X75761.gene.p01 Protein 6e-45 42
Mrub_0047 YP_003505848.1 major facilitator superfamily protein AY264780.2.gene3.p01 Protein 1e-45 42
Mrub_0047 YP_003505848.1 major facilitator superfamily protein AF090987.gene.p01 Protein 4e-39 42