Gene Information

Name : Mrub_2849 (Mrub_2849)
Accession : YP_003508616.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_013946
Putative virulence/resistance : Resistance
Product : beta-lactamase domain-containing protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 2894136 - 2895578 bp
Length : 1443 bp
Strand : +
Note : SMART: Rhodanese domain protein; SPTR: A3ZUM1 Putative uncharacterized protein; PFAM: beta-lactamase domain protein; Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279:IPR001763:IPR001307:IPR016130; KEG

DNA sequence :
ATGCTCTTCAAACACATCTACGAGGAAGGACTCGCACAGGGCAGCTACTTTATCGGCTGTCAATCGCAGGGCACCGCTAT
CGTAGTAGACCCCCGGCGCGACATCCAGGTCTACCTGGACGAGGCCCAGAAGAACGGCATGAAGATTGTGGCCGTGGCCG
AGACCCACATCCACGCCGACTACCTCTCGGGCGCCCGCGAGCTGGCCAAAGCCACCGGGGCCCGGCTCTACCTGAGCGAT
GAGGGCGACGAAAACTGGAAGTACAGGGGCCTCGAGGGTTTCGACTACCAGCTCGTGCGGGATGGTGACCAGATCCGGCT
GGGCAACATCACCCTCACGGTGGTGCACACCCCCGGCCACACCCCCGAGCACATCAGCTTTCTGGTGCAGGACGGGGCCG
CCGCCAGCGAGCCCGGCTTCTTCCTGACCGGCGACTTTGTGTTTGTGGGGGATATTGGCCGTCCCGACCTGCTGGAAGAG
GCCGCCGGCCTCCTAGGCACCGCCGAACCCGGCGCCCGGCGCATGTTCAGAAGCCTGAAGGAAAAATTCCTCACCCTGCC
CGACTATGTACAGGTCTGGCCGGGCCACGGCGCGGGTAGCGCCTGCGGGAAGGGTCTGGGGGCTGTTGCTAGCACCACGG
TGGGCTATGAGCGCCGCTTTGCCTGGTGGGCCGACTACCTGCGCACGGGCGACGAGGAAGGCTTTGTGAAGGCCCTGCTC
TCGGGCCAGCCCGAAGCCCCTTACTACTTTGCTCAGATGAAGCGGCTCAACCGCGACGGGATGCCCATCCTGGGCGACCT
GTCCATACCCCACCAGCTCACCCCCGAGCAGTTCCAGCAGAAGTTGAGCGAAGGAGCCTTGCTGGTGGATACCCGTGACA
AGCTGGCCTTCGCCGGAGGGCACCTGAAGGGGGCCATCAACATCCCGGCGGGCAAGAACTTCAGCACCTGGGCGGGCTGG
CTGCTGCCTTACGACCGCGACCTGGTGCTGCTGGCCAGCCCTGAACGGGTGGGCGAGCTGGTCAAGCAGCTCATTCGCAT
CGGGCTGGATCGGGTGGTGGGGTATATTCCGGGCCTCGAGGGCTACGCACAGGGTGAGCTCGAGACCGTTCCTCAGGTCA
CCGCAGCCCAGGCCAAAGCCCTGTGGGAAAAGGGCGAGGCCACCATTCTGGACGTGCGCGGGGCCGACGAGTACCTGGCC
GGCCACATCCCTGGGGCCCAGAACATCCACGCCGGGCGGGTGATGAACAACCTGAACCGCATCCCCAAGGACAAGCCGGT
GGTGGTGCACTGCCTGGGTGGCGACCGTTCGTCCACGGCCATTAGCGCACTGATGGGCGCGGGCTTTAGCAACCTGGTCA
ACCTCACCGGCGGCATCCGGGCCTGGCAGCAGGAGGGCTTCCCCATTGAGAAAGGCCCTTCCCGTGAGATGGTAAATGCC
TAG

Protein sequence :
MLFKHIYEEGLAQGSYFIGCQSQGTAIVVDPRRDIQVYLDEAQKNGMKIVAVAETHIHADYLSGARELAKATGARLYLSD
EGDENWKYRGLEGFDYQLVRDGDQIRLGNITLTVVHTPGHTPEHISFLVQDGAAASEPGFFLTGDFVFVGDIGRPDLLEE
AAGLLGTAEPGARRMFRSLKEKFLTLPDYVQVWPGHGAGSACGKGLGAVASTTVGYERRFAWWADYLRTGDEEGFVKALL
SGQPEAPYYFAQMKRLNRDGMPILGDLSIPHQLTPEQFQQKLSEGALLVDTRDKLAFAGGHLKGAINIPAGKNFSTWAGW
LLPYDRDLVLLASPERVGELVKQLIRIGLDRVVGYIPGLEGYAQGELETVPQVTAAQAKALWEKGEATILDVRGADEYLA
GHIPGAQNIHAGRVMNNLNRIPKDKPVVVHCLGGDRSSTAISALMGAGFSNLVNLTGGIRAWQQEGFPIEKGPSREMVNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 1e-74 41
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 8e-75 41
unnamed BAB83478.1 - Not tested SCC 12263 Protein 1e-75 41