Gene Information

Name : Mrub_2805 (Mrub_2805)
Accession : YP_003508572.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_013946
Putative virulence/resistance : Resistance
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2844318 - 2844992 bp
Length : 675 bp
Strand : +
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; InterPro IPR001789:IPR001867; KEGG: bac:BamMC406_3349 two component heavy metal response transcriptional regulator; COGs: COG0745 Response reg

DNA sequence : 
ATGAAACGTATTTTGCTGATTGAAGACGACCCCGAGATCGCACACCTCTTGCAGCTCGAGCTGGGCGAGGCCGGTTACAC
CGTGGACTGGGCCTCGGGAGGAATGTCGGGCCTGGTGCGCCTGCGCGAGGCCACACCGGATCTGGTCATCCTCGACCTAG
GCCTACCCGATCTGGACGGCGGTGAAGTAGCCCGGCGCATTCGAGCAGGCTACGAGGTGCCCATCATCGTCCTCACCGCC
GCCGATGCAGTGGAGCGCAAGGTCAGCCTGCTCTCCGACGGGGCCGACGACTACATCGTCAAGCCCTTCCACCCCGCCGA
GTTGCTGGCCCGCATCCAGGTGCAGCTCCGCCACCGTGAAGGGGGTGAGCAGATCAGCGTGGGGGGCTTGGAAGTCCACC
TAGCCAAGCGACAGGTGCTGTTCGAAGGCCAGGAGCTGCGCCTTTCACCTAAGGAATTCGAATTGCTGTCGCTTTTGGTG
AGCCGTGCGGGCAAGGTGTTCAGCCGTCAGGAGATCGAGGAGCACCTGTGGGGAAGGCAGCTCGAGCGTGACTCCAATGT
GGTCGATGTGCATATTGCCAACCTGCGCGCCAAGCTGCGCGAAGCCGGTGCTTACGGCTACCTGCGCACCGTGCGCGGGG
TGGGCTATGCCCTGCGGCAGCGCGAGGCCGAGTGA

Protein sequence : 
MKRILLIEDDPEIAHLLQLELGEAGYTVDWASGGMSGLVRLREATPDLVILDLGLPDLDGGEVARRIRAGYEVPIIVLTA
ADAVERKVSLLSDGADDYIVKPFHPAELLARIQVQLRHREGGEQISVGGLEVHLAKRQVLFEGQELRLSPKEFELLSLLV
SRAGKVFSRQEIEEHLWGRQLERDSNVVDVHIANLRAKLREAGAYGYLRTVRGVGYALRQREAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 9e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 1e-28 43
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator BAC0125 Protein 2e-27 42
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator AE015929.1.gene1106. Protein 2e-25 41
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator AF310956.2.orf0.gene Protein 4e-26 41
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator BAC0083 Protein 5e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrub_2805 YP_003508572.1 winged helix family two component transcriptional regulator VFG1389 Protein 1e-25 42