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Name : Mrub_2450 (Mrub_2450) Accession : YP_003508221.1 Strain : Meiothermus ruber DSM 1279 Genome accession: NC_013946 Putative virulence/resistance : Unknown Product : type I site-specific deoxyribonuclease HsdR family Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 2500846 - 2503974 bp Length : 3129 bp Strand : - Note : TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; InterProIPR007409:IPR006935:IPR014001:IPR014021:IPR 004473; KEGG: aba:Acid345_3755 DNA sequence : ATGGCGCAAATGACCGAATCTGTCGTTGAAGAAGCCGCCCTGGCCTGGCTCGAGGCCGCCGGTTGGCAGGTGGTACACGG CCCCGAGATTGCCCCCGACCAGCCCCAGGCCGAGCGGGCCGACTATGGTCAGGTGGTGCTCGAGCAGCGGCTGCGCGATG CGCTGGTGCGGCTTAACCCTGGGCTGCCTGCAGAGACGCTGGAGGACGCCTCCCGCAAGCTCACCCAGCCTGAGGGTTCA GACCTAATCCAACGAAACCGCGCCCTGCACCGCCTGCTGGTGAATGGCGTAAACGTGGAGTACCGCGACAAGGACGGCGA GATTCGCGGCGCACAGGCCAGAGTAATTGATTTTGACAACCCAGCCAACAACGACTGGCTGGCGGTCAATCAGTTCAGCG TTGTGGAGAGGGGTACGTTGCAACGTGCCCCATCTATGCAACGTGCCTCAACCCGCCGCCCCGACGTGGTGCTGTTCGTC AATGGCCTACCGCTGGCAGTAGTGGAGCTGAAGAACGCTGCCGACGAAGACGCGACAATCTGGACGGCGTGGCAGCAGCT CCAGACCTACCAGGCCGAAATCCCCTCGCTCTTTGTGCCCAACGCGGTGCTGGTGATTTCCGATGGGGTGGAGGCGCGCG TGGGGGTGGTGGGGGCAGGGCGGGAGTGGTTCAAGCCCTGGCGCACGGTGGCTGGCGATCGCCTGGCCGACAGCCACGTG CCCGAGTTGCAGGTGGTGCTCGAGGGGGTGTTCGCACCGCGGCGCTTCCTCGACCTGGTGCGCGACTTCATCGTGTTTGA GGATGACGGCAGCGGACGATTGATCAAGAAAATGGCGGGTTATCACCAGTTCCACGCGGTGCAGGTGGCAGTACAGGAAA CGCTGCGGGCGGCCCTGGCCTTGCGCGAGGGTAGGGGGGGCCAGTCGGGCGACCGGCGCATCGGCGTGGTCTGGCACACC CAGGGCTCGGGTAAAAGCCTGACCATGGCGTTTTACGCCGGGCGCATCATCCGCGAACCCGCCATGGAGAACCCCACCCT GGTGGTGCTCACCGACCGCAACGACCTCGACGACCAGCTTTACAGCACCTTTGCGCGTTGCCACGAGTTGCTGCGCCAGC CGCCGGTGCAGGCCGAAAGCCGCGCCCACCTGCGCGAGCTGCTCTCGGTGCAGTCGGGCGGGGTGGTCTTCACCACCATC CAGAAGTTCATGCCCGAAGAGAAAGGCGACCGCCACCCGCGGCTTTCCGAGCGGCGCAACATCGTGGTTATTGCCGACGA AGCCCATCGCAGCCAGTACGACTTCATAGATGGCTTTGCCCGCCATATGCGCGACGCCCTGCCCAACGCCTCTTTTATCG GCTTCACCGGAACCCCCATCGAGCTTCAGGATGCCAATACCCGCGCGGTGTTTGGCGATTACATCAGCATCTACGACATC CAGCGCGCCGTGGAGGACGGGGCCACCGTGCCCATCTATTACGAAAGCCGCCAGGCCAAGCTTGACCTGCCTGAGGAACT CAAGCCGAAGATTGATGAGGAATTCGAGGAAGTTACCGAGGGGGAGGAACTCGAGCGCAAGGAGAAGCTCAAGAGCAAGT GGGCGCAGCTCGAGGCCATCGTGGGTGCGGAAAGGCGGCTGCGCCTGGTGGCGAAGGATATTGTCCAGCACTTCGAACAG CGGCTCGAGGCCTTGGACGGCAAGGCCATGATTGTCTGCATGAGCCGTCGCATTTGCGTGGAACTCTACCGCGAGATTGT GCGCCTGAGGCCCCAGTGGCATCACGACGACGACGACAAAGGCGCGATCAAGATCGTGATGACCGGCTCCGCTTCCGACC CACCCGACTGGCAGCCGCACATCCGCAACAAGCCCCGCCGCGAAGCGCTGGCTAAGCGTTTCCGCGATCCCGAAGATGCC TTCAAGCTGGTCATTGTGCGCGACATGTGGCTTACCGGCTTCGACGCGCCCAGCCTGCACACCATGTACCTGGACAAGCC CATGCGTGGACACGGCCTGATGCAGGCCATCGCGCGGGTAAACCGGGTCTTCCGCGACAAGCCCGGCGGGCTGGTGGTGG ATTACCTGGGGCTGGCTACCGAGCTAAAAGCCGCGCTGGCTACCTACACCGAGAGCGGCGGCACCGGACGCACCGCGCTC AATCAGGAAGAAGCGGTGGCGCTCATGCGCGAGAAATACGAGATTTGCCGTGGCCTTTTTTACGGCTTCGACTGGTCGAG GTGGGTTACGGGCACGCCGGCGGAACGGCTGAGCCTTCTGCCTGCCGCGCAGGAGCACATCCTCGCTCAGGAGAACGGCA AGGATCGGCTGCTGCGTGCGGCGCGCGAGCTGTCACAAGCGTTCGCGCTGGCTGTGCCGCATGAAGAGGCCCTGCGCATC CGAGACGACGTGGCCTTCTTCCAGGCCGTGCAAGCGGTGCTGGCTAAACGCGCGCCAGGCCAGGCACGGCCCGAGGAGGA ACTCGAGCAGGCCGTGCGCCAGATAATCGCCCGTGCGGTGGCACCCGAGGGTGTGGTGGACATTTTCGCAGCAGCGGGGC TCAAGAGGCCGGACATCTCCATACTCTCCGATGAGTTTTTGTCCGAGGTGCGGGGGATGCCGCAGAAAAACCTGGCGGTA GAGCTATTGCAAAAGCTGCTTAAAGGAGAGATTCGGGCTCGAGGACAGAAGAACCTGGTGCAGGCCAGGTCGTTTGCCGA GATGCTCGAGCGAACCATCCGCCGTTACCAGAACCGGGCCATCGAGGCCGCCCAGGTGATTGAAGAACTCATCGCGCTCG CCAGGGATATGCGCGAAGCCAATGCCCGTGGCGAGAAACTCGGCTTATCCGAGGACGAACTGGCCTTCTACGATGCCCTC GAGGCCAACGACAGCGCGGTCAAGGTGCTGGGCGACGCAACCTTGCGGGAAATTGCCCGTGAACTGGTTCAGACGGTGCG CAACAATGTAACCCTCGACTGGACCTTGCGTGAGAATGTGCGGGCGCAGTTGCGCGTGCTGGTCAAACGCACGCTGCGCA AATACGGCTACCCACCCGACAAGCAGGAGAAAGCCACCCAGACGGTACTGGAGCAAGCTGCGCTACTGTCGGCGCAGTGG GCAGCCTAG Protein sequence : MAQMTESVVEEAALAWLEAAGWQVVHGPEIAPDQPQAERADYGQVVLEQRLRDALVRLNPGLPAETLEDASRKLTQPEGS DLIQRNRALHRLLVNGVNVEYRDKDGEIRGAQARVIDFDNPANNDWLAVNQFSVVERGTLQRAPSMQRASTRRPDVVLFV NGLPLAVVELKNAADEDATIWTAWQQLQTYQAEIPSLFVPNAVLVISDGVEARVGVVGAGREWFKPWRTVAGDRLADSHV PELQVVLEGVFAPRRFLDLVRDFIVFEDDGSGRLIKKMAGYHQFHAVQVAVQETLRAALALREGRGGQSGDRRIGVVWHT QGSGKSLTMAFYAGRIIREPAMENPTLVVLTDRNDLDDQLYSTFARCHELLRQPPVQAESRAHLRELLSVQSGGVVFTTI QKFMPEEKGDRHPRLSERRNIVVIADEAHRSQYDFIDGFARHMRDALPNASFIGFTGTPIELQDANTRAVFGDYISIYDI QRAVEDGATVPIYYESRQAKLDLPEELKPKIDEEFEEVTEGEELERKEKLKSKWAQLEAIVGAERRLRLVAKDIVQHFEQ RLEALDGKAMIVCMSRRICVELYREIVRLRPQWHHDDDDKGAIKIVMTGSASDPPDWQPHIRNKPRREALAKRFRDPEDA FKLVIVRDMWLTGFDAPSLHTMYLDKPMRGHGLMQAIARVNRVFRDKPGGLVVDYLGLATELKAALATYTESGGTGRTAL NQEEAVALMREKYEICRGLFYGFDWSRWVTGTPAERLSLLPAAQEHILAQENGKDRLLRAARELSQAFALAVPHEEALRI RDDVAFFQAVQAVLAKRAPGQARPEEELEQAVRQIIARAVAPEGVVDIFAAAGLKRPDISILSDEFLSEVRGMPQKNLAV ELLQKLLKGEIRARGQKNLVQARSFAEMLERTIRRYQNRAIEAAQVIEELIALARDMREANARGEKLGLSEDELAFYDAL EANDSAVKVLGDATLREIARELVQTVRNNVTLDWTLRENVRAQLRVLVKRTLRKYGYPPDKQEKATQTVLEQAALLSAQW AA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 50 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 47 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 47 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 47 |
